Inhibitor of Growth Family, Member 4 (ING4) ELISA Kits

ING4 encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. Zusätzlich bieten wir Ihnen Inhibitor of Growth Family, Member 4 Antikörper (69) und Inhibitor of Growth Family, Member 4 Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
ING4 51147 Q9UNL4
Anti-Maus ING4 ING4 28019 Q8C0D7
Anti-Ratte ING4 ING4 297597  
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Human 11.75 pg/mL 47-3000 pg/mL Typical standard curve 96 Tests 15 bis 18 Tage
$910.56
Details

Am meisten referenzierte Inhibitor of Growth Family, Member 4 ELISA Kits

  1. Human ING4 ELISA Kit für Sandwich ELISA - ABIN816517 : Zou, Han, Zhao, Yu, Bai, Yao, Gao, Cao, Zheng: Change of ranibizumab-induced human vitreous protein profile in patients with proliferative diabetic retinopathy based on proteomics analysis. in Clinical proteomics 2018 (PubMed)

Weitere ELISA Kits für Inhibitor of Growth Family, Member 4 Interaktionspartner

Human Inhibitor of Growth Family, Member 4 (ING4) Interaktionspartner

  1. We also present the current understanding concerning the role of ING4 in the development of neoplastic and non-neoplastic diseases. These studies offer inspiration for pursuing novel therapeutics for various cancers.

  2. Splicing type of ING4 affects the translocation of ING4 proteins into the nucleus.

  3. Both CELSR2 and ING4 display increased cytoplasmic staining in breast cancer cells compared to benign epithelium, suggesting a possible role of both genes in the pathogenesis of human mammary neoplasia.

  4. These results demonstrated that overexpression of ING4 can induce the apoptosis of melanoma cells and CD3+ T cells through signaling pathways such as the Fas/FasL pathway, and that ING4 gene therapy for melanoma treatment is a novel approach.

  5. Inhibitor of growth 4 upregulation plus radiotherapy induced synergistic tumor suppression in SPC-A1 xenografts implanted in athymic nude mice. Thus, the restoration of inhibitor of growth 4 function might provide a potential strategy for non-small cell lung cancer radiosensitization.

  6. Results found that ING4 expression was significantly reduced in CRC tissues and associated with increased lymph node metastasis, advanced TNM stage and poor overall survival. Also, ING4 suppressed CRC angiogenesis by inhibition of Sp1 expression and transcriptional activity through destabilization and ubiquitin degradation and down-regulation of Sp1 downstream pro-angiogenic factors MMP-2 and COX-2.

  7. Low ING4 expression is associated with malignant phenotype and temozolomide chemoresistance in glioblastomas.

  8. ING4 directly binds the Miz1 promoter and is required to induce Miz1 mRNA and protein expression during luminal cell differentiation.

  9. The oncogenic role of miR-330 in Hepatocellular Carcinoma Cells is linked to downregulation of ING4.

  10. ING4 binds double-stranded DNA through its central region with micromolar affinity.

  11. results indicate that the combination of ING4 and PTEN may provide an effective therapeutic strategy for HCC

  12. ING4 can facilitate cancer cell sensitivity to chemotherapy and radiotherapy. Although ING4 loss is observed for many types of cancers, increasing evidences show that ING4 can be used for gene therapy. In this review, the recent progress of ING4 regulating tumorigenesis is discussed

  13. ING4 inhibits CRC invasion and metastasis probably via a switch from mesenchymal marker N-cadherin to epithelial marker E-cadherin through downregulation of Snail1 epithelial-mesenchymal transition (EMT)-inducing transcription factor (EMT-TF).

  14. Data show that Ras protein regulates inhibitor of growth protein 4 (ING4)-thymine-DNA glycosylase (TDG)-Fas protein axis to promote apoptosis resistance in pancreatic cancer.

  15. MiR-761 directly targeted ING4 and TIMP2.

  16. Data suggest a close connection between aberrant ING4 expression and the carcinogenesis of human bladder cells.

  17. This review summarizes the recent published literature that investigates the role of ING4 in regulating tumorigenesis and progression, and explores its potential for cancer treatment. [review]

  18. SCF(JFK) as a bona fide E3 ligase for ING4 and unraveled the JFK-ING4-NF-kappaB axis as an important player in the development and progression of breast cancer

  19. work suggests that ING4 can suppress osteosarcoma progression through signaling pathways such as mitochondria pathway and NF-kappaB signaling pathway and ING4 gene therapy is a promising approach to treating osteosarcoma.

  20. The enhanced antitumor activity generated by Ad.RGD-ING4-PTEN was closely associated with activation of the intrinsic and extrinsic apoptotic pathways and additive inhibition of tumor angiogenesis both in vitro and in vivo.

Mouse (Murine) Inhibitor of Growth Family, Member 4 (ING4) Interaktionspartner

  1. IL-6 Receptor is overexpressed in glioma, and it can be used for targeted delivery of the therapeutic ING4 to the tumor.

  2. ING4 might suppress proliferation and enhance apoptosis in human malignant melanoma cells by activating Fas-induced apoptosis in a caspase-8-dependent pathway.

  3. Inhibitor of growth-4 promotes IkappaB promoter activation to suppress NF-kappaB signaling and innate immunity

  4. Report down-regulation of the inhibitor of growth family member 4 (ING4) in different forms of pulmonary fibrosis.

Inhibitor of Growth Family, Member 4 (ING4) Antigen-Profil

Beschreibung des Gens

This gene encodes a tumor suppressor protein that contains a PHD-finger, which is a common motif in proteins involved in chromatin remodeling. This protein can bind TP53 and EP300/p300, a component of the histone acetyl transferase complex, suggesting its involvement in the TP53-dependent regulatory pathway. Multiple alternatively spliced transcript variants have been observed that encode distinct proteins.

Genbezeichner und Symbole assoziert mit ING4

  • inhibitor of growth family, member 4 (ing4) Antikörper
  • inhibitor of growth family, member 4 (ING4) Antikörper
  • inhibitor of growth family member 4 (ING4) Antikörper
  • inhibitor of growth family, member 4 (Ing4) Antikörper
  • D6Wsu147e Antikörper
  • D6Xrf92 Antikörper
  • ING4 Antikörper
  • my036 Antikörper
  • p29ING4 Antikörper
  • wu:fb11d09 Antikörper
  • wu:fb50e02 Antikörper
  • zgc:110619 Antikörper

Bezeichner auf Proteinebene für ING4

inhibitor of growth protein 4 , inhibitor of growth family, member 4 , brain my036 protein , candidate tumor suppressor p33 ING1 homolog , p29ING4 , ING1-like protein

GENE ID SPEZIES
322113 Danio rerio
749471 Pan troglodytes
100340491 Oryctolagus cuniculus
51147 Homo sapiens
418281 Gallus gallus
477712 Canis lupus familiaris
28019 Mus musculus
297597 Rattus norvegicus
532483 Bos taurus
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