Homeobox C8 Proteine (HOXC8)

HOXC8 belongs to the homeobox family of genes. Zusätzlich bieten wir Ihnen Homeobox C8 Antikörper (75) und und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HOXC8 3224 P31273
HOXC8 15426 P09025
HOXC8 24460  
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Top Homeobox C8 Proteine auf antikoerper-online.de

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
Hefe Ratte His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Zebrafisch His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Takifugu rubripes His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

HOXC8 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Homeobox C8 (HOXC8) Interaktionspartnern

Human Homeobox C8 (HOXC8) Interaktionspartner

  1. Results show that HOXC8 is consistently downregulated in stem/progenitor cells of all breast molecular subtypes, thus representing a putative tumor suppressor candidate. Also, downregulated expression of HOXC8 is associated with DNA methylation at the gene promoter and expression of miR196 family members. Taken together, study establishes HOXC8 as a suppressor of stemness and transformation in the mammary gland lineage.

  2. Owing to the overexpression of Homeobox C8 (HOXC8), findings implied that HOXC8 is involved in the progression of epithelial ovarian cancer (EOC) and could be a potential therapeutical approach of EOC.

  3. High expression of HOXC8 is associated with laryngeal squamous cell carcinoma.

  4. HOXC8 knockdown led to inhibition of tumor cell proliferation and migration in vitro by inhibiting MMP-9 expression and tumor growth in vivo. The results strongly suggest that HOXC8 is involved in the tumorigenesis of osteosarcoma and might serve as a novel predictor for patients' outcome.

  5. embigin is regulated by HOXC8 and its loss plays an important role in the progression of breast tumors

  6. Ectopic expression of HoxC8 inhibits nasopharyngeal carcinoma cell growth in vitro and in vivo, modulates glycolysis and regulates the expression of tricarboxylic acid (TCA) cycle-related genes.

  7. Upregulated HOXC8 expression was associated with oxaliplatin resistance in hepatocellular carcinoma.

  8. miR-196a was over-expressed in cervical cancer cells, while an absence of HOXC8 expression was observed.

  9. HOXC8 promotes breast tumorigenesis by transcriptionally facilitating cadherin-11 expression.

  10. HOXC8 can be used as a prognostic marker in esophageal squamous cell carcinoma

  11. HOXC8 expression is inversely related to pancreatic ductal adenocarcinoma progression and metastasis.

  12. a complex role for HOXC8 in prostate cancer, promoting invasiveness while inhibiting AR-mediated gene induction at androgen response element-regulated genes associated with differentiated function of the prostate

  13. Ratio of microRNA to HOXC8 mRNA may be an indicator of the metastatic capability of breast tumors.

  14. overexpression associated with loss of tumor differentiation in human prostate cancer; may play role in acquisition of invasive/metastatic phenotype

  15. Androgen-independent cell line DU145 cells lack PLZF gene expression, resulting in the upregulation of Pbx1 and HoxC8 expression. The Pbx1-HoxC8 heterocomplex may lead to androgen-independent growth in prostate cancer.

Mouse (Murine) Homeobox C8 (HOXC8) Interaktionspartner

  1. In presence of these inducing agents, lipid accumulation as well as expression of HoxA1, HoxA5, HoxC4 &HoxC8 markedly enhanced. Irrespective of presence or absence of T3, insulin down regulates HoxA10. T3 results in over expression of HoxA5, HoxC4 and HoxC8 genes, whereas insulin up regulates expression of only HoxC8

  2. Hoxc8 initiates an ectopic mammary program by regulating Fgf10 and Tbx3 expression and Wnt/beta-catenin signaling

  3. Cdx1 regulation on HoxC8 expression and suggest the possibility that the temporal changes in Cdx activity levels during gastrulation, combined with differential DNA binding affinity, might play a role in the establishment of Hox sequential activation.

  4. Hoxc8 downregulates Mgl1 tumor suppressor gene expression and reduces its concomitant function on cell adhesion.

  5. Data provide the basis for future studies in pathogenesis of cartilage defects in Hoxc8- and Hoxd4-transgenic mice.

  6. Hoxc8, when over-expressed in C3H10T1/2 or C2C12 cells, suppressed basal Smad6 promoter activity and its mRNA expression

  7. Hoxc8 regulation is essential for osteoblast differentiation.

  8. Pcna is a direct downstream target of Hoxc8.

  9. interaction with smad1 stimulates bone development

  10. remodeling of Hox regulatory elements in different species has played a significant role in generating morphological diversity

  11. In mice, Hoxc8 has a role in the formation of the vertebrae and ribs and may be involved in the differentiation of the kidney.

  12. OPN is a direct transcriptional target of Hoxc8

  13. Raldh2L-/- phenotype relies in part on the deregulation of Hoxc8, which in turn regulates the RA receptor RARbeta

  14. the genes described here should aid in the understanding of global regulatory networks of Hox genes and to provide valuable insight into the molecular basis of Hoxc8 in development and carcinogenesis

  15. Precise temporal expression of Hoxc8 is important for determining the correct identity of the vertebral column in early embryos.

  16. These studies document a functional role for Ap2delta in recruiting histone methyltransferases to specific gene targets, such as Hoxc8.

  17. These results indicate that the 16 amino acid third helix is the key element responsible for the membrane transduction activity of Hoxc8 proteins.

  18. Our results provide evidence for a role for Hoxc8 in controlling cell cycle progression

Xenopus laevis Homeobox C8 (HOXC8) Interaktionspartner

  1. Cdx1 binds directly these responsive elements during embryogenesis, as part of the mechanism for the timely activation of HoxC8 expression.

Zebrafish Homeobox C8 (HOXC8) Interaktionspartner

  1. Remodeling of Hox regulatory elements in different species has played a significant role in generating morphological diversity.

Homeobox C8 (HOXC8) Protein Überblick

Protein Überblick

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXC genes located in a cluster on chromosome 12. The product of this gene may play a role in the regulation of cartilage differentiation. It could also be involved in chondrodysplasias or other cartilage disorders.

Genbezeichner und Symbole assoziert mit Homeobox C8 Proteine (HOXC8)

  • homeobox C8 (HOXC8)
  • homeobox C8 (Hoxc8)
  • homeobox C8 (hoxc8)
  • homeobox C8 S homeolog (hoxc8.S)
  • homeobox protein pXhoxc8 (xhoxc8)
  • homeobox C8a (hoxc8a)
  • cb341 Protein
  • D130011F21Rik Protein
  • FrHOXC-8 Protein
  • Hox-3.1 Protein
  • hox3 Protein
  • hox3a Protein
  • Hox3r4 Protein
  • hoxc-8 Protein
  • hoxc8 Protein
  • HoxC8a Protein
  • MGC89609 Protein
  • xhoxc8 Protein
  • z-179 Protein
  • zgc:91832 Protein

Bezeichner auf Proteinebene für Homeobox C8 Proteine (HOXC8)

Hox-3.1, mouse, homolog of , homeo box 3A , homeo box C8 , homeobox protein Hox-3A , homeobox protein Hox-C8 , homeobox protein Hox-3.1 , homeobox protein M31 , cHoxc-8 , homeobox C8 , Homeobox gene C8 , homeobox protein R4 , homeobox protein pXhoxc8 , homeobox c8a , homeobox gene C-8 , homeobox protein Hox-C8a , Homeobox protein Hox-C8a , homeobox protein HOXC-8 , homeobox protein HoxC8a , LOW QUALITY PROTEIN: homeobox protein Hox-C8

3224 Homo sapiens
15426 Mus musculus
395711 Gallus gallus
448482 Xenopus (Silurana) tropicalis
607052 Canis lupus familiaris
100158353 Xenopus laevis
24460 Rattus norvegicus
399084 Xenopus laevis
449648 Danio rerio
100295249 Bos taurus
101078676 Takifugu rubripes
100724872 Cavia porcellus
101122179 Ovis aries musimon
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