anti-Homeobox A9 (HOXA9) Antikörper

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Zusätzlich bieten wir Ihnen HOXA9 Proteine (10) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
HOXA9 3205 P31269
HOXA9 15405 P09631
HOXA9 500126  
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Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-HOXA9 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:1562500  Positive Control:  721_B cell lysate 100 μL 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB Anti- HOXA9 antibody, Western blotting All lanes: Anti HOXA9  at 0.5ug/ml Lane 1: Rat Testis Tissue Lysate at 50ug Lane 2: HEPG2 Whole Cell Lysate at 40ug Lane 3: HEPA Whole Cell Lysate at 40ug Predicted bind size: 30KD Observed bind size: 30KD Anti- HOXA9 antibody, Western blotting All lanes: Anti HOXA9  at 0.5ug/ml WB: Recombinant Human HOXA9 Protein 0.5ng Predicted bind size: 38KD Observed bind size: 38KD 100 μg 4 bis 6 Tage
Maus Ziege Unkonjugiert ELISA, WB   100 μg 6 bis 7 Tage
Maus Ziege Unkonjugiert ELISA, WB   100 μg 6 bis 7 Tage
Human Ziege Unkonjugiert ELISA, WB Western Blot (2μg/ml) staining of Moue Spleen lysate (35μg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg 2 bis 3 Tage
Fledermaus Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
Huhn Kaninchen Unkonjugiert IF, WB 200 μg 11 bis 14 Tage
Human Kaninchen Unkonjugiert ELISA, ICC, IF, IHC, WB Western blot analysis of extracts of SW620 , using HOXA9 antibody. The lane on the left is treated with the antigen-specific peptide. ABIN6276949 staining HepG2? cells by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) antibody(Cat.# S0006), diluted at 1/600, was used as secondary antibod 100 μL 11 bis 12 Tage
Human Kaninchen Unkonjugiert EIA, FACS, WB Flow cytometric analysis of A375 cells using HOXA9 / HOX1G Antibody (C-term) Cat.-No AP52077PU-N AP52077PU-N (right histogram) compared to a negative control cell (left histogram). FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis. Western blot analysis of HOXA9 / HOX1G Antibody (C-term) in A2058 cell line lysates (35ug/lane). HOXA9 (arrow) was detected using the purified Pab. 0.4 mL 6 bis 8 Tage
Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of SW620 cells, using HOXA9 antibody (ABIN1873074) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. 100 μL 11 bis 13 Tage

Am meisten referenzierte anti-HOXA9 Antikörper

  1. Human Polyclonal HOXA9 Primary Antibody für ICC, IF - ABIN4319699 : Molino, Jabès, Bonnet, Gaudin, Bernard, Benech, Khrestchatisky: Gene expression comparison reveals distinct basal expression of HOX members and differential TNF-induced response between brain- and spinal cord-derived microvascular endothelial cells. in Journal of neuroinflammation 2016 (PubMed)
    Show all 3 Pubmed References

  2. Cow (Bovine) Polyclonal HOXA9 Primary Antibody für WB - ABIN2778526 : Whelan, Ludwig, Bertrand: HoxA9 induces insulin-like growth factor-1 receptor expression in B-lineage acute lymphoblastic leukemia. in Leukemia 2008 (PubMed)
    Show all 2 Pubmed References

  3. Human Monoclonal HOXA9 Primary Antibody für IF, ELISA - ABIN561318 : Storlie, Jackson, Hutchinson, Grose: Delayed biosynthesis of varicella-zoster virus glycoprotein C: upregulation by hexamethylene bisacetamide and retinoic acid treatment of infected cells. in Journal of virology 2006 (PubMed)

  4. Mouse (Murine) Polyclonal HOXA9 Primary Antibody für ELISA, WB - ABIN4319694 : Hu, Fong, Ferrell, Largman, Shen: HOXA9 modulates its oncogenic partner Meis1 to influence normal hematopoiesis. in Molecular and cellular biology 2009 (PubMed)

Weitere Antikörper gegen HOXA9 Interaktionspartner

Human Homeobox A9 (HOXA9) Interaktionspartner

  1. we show that HOXA9 and JAK3/STAT5 are bona fide cooperating factors in driving leukemia development and that the cooperation is situated at the transcriptional level where STAT5 and HOXA9 co-occupy similar genomic regions

  2. These data indicate that NPMc+ leukemic cell survival requires upregulation of PBX3 and HOXA9.

  3. High HOXA9 expression is associated with increased metabolic dysregulation and leukemogenesis.

  4. Results identified HOXA9 as a potential target of miR873. 3'UTR of HOXA9 was recognized and targeted by miR873 in osteosarcoma (OS) cells. HOXA9 expression was upregulated in OS tissues, and inversely correlated with miR873 expression.

  5. HOXA9, RASSF1A and SCGB3A1 promoter methylation significantly associated with testicular germ cell tumor stage.

  6. this study shows HOXA9 methylation and blood vessel invasion in formalin-fixed paraffin-embedded tissues for prognostic stratification of stage I lung adenocarcinoma patients

  7. that therapeutic targeting of HOXA9-dependent enhancer reorganization can be an effective therapeutic strategy in acute leukemia with HOXA9 overexpression

  8. High HOXA9 expression is associated with hematogical malignancy.

  9. Downregulation of HOXA9 in myeloid leukaemia cells led to increased differentiation capacity in vitro.

  10. Based on the human, animal and cellular data, the transcription factor HOXA9 may promote the expression of pro-myopia genes and retinal pigment epithelial proliferation, which eventually contribute to myopia development.

  11. HOXA9 inhibits HIF1A-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development.

  12. MiR-182/HOXA9 was involved in the process of RUNX3-mediated GC tumor growth.

  13. The present study demonstrated that miR-139-5p, functioning as a suppressor in the tumorigenesis process, suppressed oral squamous carcinoma cells mobility by targeting HOXA9 directly.

  14. NHA9 (NUP98-HOXA9 fusion protein) deregulates the expression of key leukemic genes, including MEIS1-HOXA9-PBX3 complex, through the enhancer binding and the direct interaction of the fusion protein with HDAC and p300 transcriptional regulators

  15. Results show that a combination of HOXA9 and HOXA10 promoter methylation markers is significantly associated with the prognosis of breast cancer patients a subtype-independent manner.

  16. knockdown of HOXA9 abrogated NAC1induced drug resistance.

  17. HOXA9 expression is upregulated in three-dimensional organotypic culture of claudin-low breast cancer cells.

  18. HOXA9 transcriptionally regulated EPHB4 expression to modulate trophoblasts migration and invasion, which may suggest a contribution of HOXA9-EPHB4 in the poor placentation in the pathogenesis of preeclampsia.

  19. Overexpression of HOXA4 and HOXA9 contributes to self-renewal and overpopulation of stem cells in colorectal cancers.

  20. HOTTIP/WDR5/HOXA9/Wnt axis contributes to pancreatic tumor stem cell stemness.

Mouse (Murine) Homeobox A9 (HOXA9) Interaktionspartner

  1. DOT1L, LSD1, and HDAC Class I Inhibitors Reduce HOXA9 Expression in MLL-AF9 Rearranged Leukemia Cells, But Dysregulate the Expression of Many Histone-Modifying Enzymes

  2. HOXA9 inhibits HIF1A-mediated glycolysis through interacting with CRIP2 to repress cutaneous squamous cell carcinoma development.

  3. Beta-catenin regulates expression of downstream targets of a key transcriptional memory gene, Hoxa9 that is highly enriched in myeloid leukemia cancer stem cells and helps sustain leukemic self-renewal.

  4. The analysis points to a critical role for Hoxa9 and PU.1 in distal regulation of c-myb expression in murine myeloid cells during iL-6-induced cell differentiation.

  5. the Hoxa9- and Meis1-associated upregulation of Flt3 is a passive event with regard to leukemia development in mice and with limited relevance to the AML pathology.

  6. the cohesin complex regulates PRC2 targeting to silence Hoxa7 and Hoxa9 and negatively regulate self-renewal. Our studies identify a novel epigenetic mechanism underlying leukemogenesis in AML patients with cohesin mutations.

  7. data delineate an altered epigenetic stress response in activated satellite cells from aged mice, which limits satellite cell function and muscle regeneration by Hoxa9-dependent activation of developmental pathways

  8. Pbx3 contributes to Hoxa9 leukemogenesis through stabilization of the Meis1 protein.

  9. IGF-1 is a direct HOXA9 target important for hematopoietic transformation.

  10. deficiency of tumor suppressor prep1 accelerates the onset of meis1- hoxa9 leukemogenesis

  11. Hoxa9 collaborates with E2A-PBX1 in mouse B cell leukemia in association with Flt3 activation and decrease of B cell gene expression.

  12. results suggest a previously unidentified role for C/EBPalpha in maintaining the proliferation required for Hoxa9/Meis1-mediated leukemogenesis

  13. This is the first description of a molecular link between HoxA9 and the regulation of Bcl-2 family members in acute myeloid leukemia.

  14. HOXA9 may, therefore, stimulate ovarian cancer progression by promoting an immunosuppressive microenvironment via paracrine effects on peritoneal macrophages.

  15. there is an extremely early checkpoint in hematopoietic differentiation critical for B and T lymphopoiesis that can only be transversed through the cooperative action of Hoxa9 and Flt3 signaling.

  16. High Hoxa9 transgene expression in the embryonic hematopoietic compartment was lethal. Mice with lower levels of Hoxa9 developed a precursor-T-cell lymphoblastic leukemia/lymphoma, accompanied by spontaneous Notch1 mutations.

  17. These findings reveal distinct requirements for Hoxa9 or Hoxa9/Flt3 molecular circuits in regulation of B versus natural killer and dendritic cell development in bone marrow.

  18. Collectively, our data suggest that PBX3 is a critical cofactor of HOXA9 in leukemogenesis.

  19. Loss of Scmh1 caused derepression of Hoxb4 and Hoxa9, direct targets of Polycomb-group complex 1-mediated transcriptional silencing in hematopoietic cells.

  20. Female nude mice inoculated i.p. with MOSEC cells that overexpressed Hoxa9 developed larger tumors and had significantly shorter survival times than controls.

HOXA9 Antigen-Profil

Protein Überblick

In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.

Genbezeichner und Symbole assoziert mit anti-Homeobox A9 (HOXA9) Antikörper

  • homeobox A9 (HOXA9) Antikörper
  • homeobox protein Hox-A9 (LOC745701) Antikörper
  • homeobox A9 (hoxa9) Antikörper
  • homeobox A9 S homeolog (hoxa9.S) Antikörper
  • homeobox A9 (Hoxa9) Antikörper
  • homeobox A7 (Hoxa7) Antikörper
  • ABD-B Antikörper
  • D6a9 Antikörper
  • Hox-1.7 Antikörper
  • HOX1 Antikörper
  • HOX1.7 Antikörper
  • HOX1G Antikörper
  • Hox1r5 Antikörper
  • HOXA-9 Antikörper
  • Hoxa7 Antikörper
  • HOXA9 Antikörper
  • hoxa9-A Antikörper
  • xhoxa9 Antikörper
  • XlHbox-6 Antikörper
  • XlHbox6 Antikörper

Bezeichner auf Proteinebene für anti-Homeobox A9 (HOXA9) Antikörper

homeobox A9 , homeobox protein Hox-A9 , HOXA9A , XIHbox 6 , homeobox protein Hox-1G , homeodomain protein HOXA9 , homeo box A9 , homeobox protein Hox-1.7 , Homeobox gene A7 , homeobox protein Hox-1.1 , homeobox protein Hox-A7 , homeobox protein R5 , hox-1.1 , homeobox protein A9

482372 Canis lupus familiaris
699729 Macaca mulatta
745701 Pan troglodytes
100137363 Papio anubis
100328788 Oryctolagus cuniculus
100049208 Oryzias latipes
100037070 Xenopus laevis
396096 Gallus gallus
3205 Homo sapiens
15405 Mus musculus
500126 Rattus norvegicus
510459 Bos taurus
100725915 Cavia porcellus
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