Histidyl TRNA Synthetase (HARS) ELISA Kits

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. Zusätzlich bieten wir Ihnen Histidyl TRNA Synthetase Antikörper (76) und Histidyl TRNA Synthetase Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
HARS 3035 P12081
HARS 15115 Q61035
Anti-Ratte HARS HARS 307492  
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Top Histidyl TRNA Synthetase ELISA Kits auf antikoerper-online.de

Showing 3 out of 6 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.9 pg/mL 15.6-1000 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Rind (Kuh)
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für Histidyl TRNA Synthetase Interaktionspartner

Human Histidyl TRNA Synthetase (HARS) Interaktionspartner

  1. This study suggests that the human HisRS genes, while descending from a common ancestor with dual function for both types of tRNA(His), have acquired highly specialized tRNA recognition properties through evolution.

  2. Despite the similar kinetics, differential scanning fluorimetry revealed that Y454S is less thermally stable than Wild Type HARS, and cells from Y454S patients grown at elevated temperatures demonstrate diminished levels of protein synthesis compared to those of Wild Type cells. The thermal sensitivity associated with the Y454S mutation represents a biochemical basis for understanding Usher Syndrome Type IIIB.

  3. Loss of function mutations in histidyl-tRNA synthetase cause a spectrum of inherited peripheral neuropathies

  4. Data suggest that by comparing human and trypanosomatid histidyl-tRNA synthetases (HisRS) may provide opportunities for developing specific inhibitors of Trypanosoma brucei HisRS.

  5. Secreted histidyl-tRNA synthetase splice variants elaborate major epitopes for autoantibodies in inflammatory myositis.

  6. Data indicate that higher anti-Jo1 levels were associated with disease severity in antisynthetase syndrome (ASS (zeige ASS1 ELISA Kits)) patients.

  7. Findings suggest that histidyl-tRNA synthetase (HARS) is associated with axonal peripheral neuropathy.

  8. Study identified sequence variants in the known disease-causing genes SLC6A3 (zeige SLC6A3 ELISA Kits) and FLVCR1 (zeige FLVCR1 ELISA Kits), and present evidence to strongly support the pathogenicity of variants identified in TUBGCP6 (zeige TUBGCP6 ELISA Kits), BRAT1 (zeige C7orf27 ELISA Kits), SNIP1 (zeige SNIP1 ELISA Kits), CRADD (zeige CRADD ELISA Kits), and HARS.

  9. genomic organization of the HARS locus and mapping of transcripts originating from a bi-directional promoter controlling the differential expression of these gene

  10. Demonstrating histidyl-tRNA synthetase (Jo-1)-specific T cell responses represents a key step in establishing the hypothesis that Jo-1 drives T cell-mediated autoimmunity in Jo-1+ polymyositis.

Mouse (Murine) Histidyl TRNA Synthetase (HARS) Interaktionspartner

  1. AA 60-90 of HRS were absolutely required for in vitro as well as in vivo signaling via MyD88 (zeige MYD88 ELISA Kits)-dependent TLR pathways to case myositis.

Histidyl TRNA Synthetase (HARS) Antigen-Profil

Beschreibung des Gens

Aminoacyl-tRNA synthetases are a class of enzymes that charge tRNAs with their cognate amino acids. The protein encoded by this gene is a cytoplasmic enzyme which belongs to the class II family of aminoacyl-tRNA synthetases. The enzyme is responsible for the synthesis of histidyl-transfer RNA, which is essential for the incorporation of histidine into proteins. The gene is located in a head-to-head orientation with HARSL on chromosome five, where the homologous genes share a bidirectional promoter. The gene product is a frequent target of autoantibodies in the human autoimmune disease polymyositis/dermatomyositis. Several transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit HARS

  • histidyl-tRNA synthetase (HARS) Antikörper
  • histidyl-tRNA synthetase (Hars) Antikörper
  • Dnd1 Antikörper
  • HARSL Antikörper
  • HRS Antikörper
  • MMHRS Antikörper
  • USH3B Antikörper

Bezeichner auf Proteinebene für HARS

HisRS , histidine translase , histidine--tRNA ligase, cytoplasmic , hisRS , histidine tRNA ligase , histidyl-tRNA synthetase, cytoplasmic , dead end homolog 1 , Histidyl-tRNA synthetase, cytoplasmic

478034 Canis lupus familiaris
3035 Homo sapiens
15115 Mus musculus
307492 Rattus norvegicus
510937 Bos taurus
100173931 Pongo abelii
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