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HDC encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Zusätzlich bieten wir Ihnen Histidine Decarboxylase Proteine (18) und Histidine Decarboxylase Kits (10) und viele weitere Produktgruppen zu diesem Protein an.
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Dog (Canine) Polyclonal HDC Primary Antibody für IHC (fro), IF - ABIN115730
Dartsch, Persson: Recombinant expression of rat histidine decarboxylase: generation of antibodies useful for western blot analysis. in The international journal of biochemistry & cell biology 1998
Show all 4 Pubmed References
genes encoding for proteins involved in histamine signaling [histidine decarboxylase (hdc), histamine-gated chloride channel (zeige CLCA1 Antikörper) subunit 1 (hisCl1), ora (zeige RHO Antikörper) transientless (ort)] cause abnormal temperature preferences
Ethanol upregulates histidine decarboxylase expression in neural brain networks.
The H3 receptor is upregulated in the striatum in the Hdc KO mouse model of tic disorders.
Lack of endogenous histamine in NOD HDC(-/-) mice decreased the incidence of diabetes in relation to their wild-type counterpart.
the structure and function of the retina in mice that lacked expression of the rate limiting enzyme in the formation of histamine, histidine decarboxylase (Hdc-/- mouse), were investigated.
SDS (zeige SDS Antikörper) induces itch through increased production of epidermal histamine, which results from an increase in the gene expression and post-translation processing of L-histidine decarboxylase.
HDC, whose expression is remarkably downregulated during the first few days after birth in dermal cells of mice, plays essential roles in the hair-inducing ability of newborn mouse dermal cells
An increased expression of H3 receptors in HDC KO mice without any changes in the spontaneous firing of "histaminergic" neurons without histamine and their responses to the H3 receptor agonist (R)-alpha-methylhistamine.
Histidine decarboxylase was found at comparably high levels in mouse striatum.
There was no difference in the levels of vascular endothelial growth factor (zeige VEGF Antikörper) between HDC-/- or wild-type mice, either in the lung or in bronchoalveolar-lavage cells.
HDC-/- mice showed reduced severity of K/BxN serum-induced arthritis.
in 12 day old embryonic stem cells histidine decarboxylase was confined to peripheral cells and small clusters of cells, inner cells were usually negative for it
Human histidine decarboxylase (HDC) and dopa decarboxilase (DDC (zeige DDC Antikörper)) are highly homologous enzymes responsible for the synthesis of biogenic amines (BA) like histamine, and serotonin and dopamine, respectively. This review summarizes the analogies and differences in their origin as well as their common pathophysiological scenarios. [review]
a Possible Role for the Histidine Decarboxylase Gene in Tourette Syndrome in the Chinese Han Population
Human enterochromaffin-like cells appear to partially co-express VMAT-2 and HDC. Co-expression of VMAT-2 and HDC might be required for increased histamine production in patients with gastric neuroendocrine tumors.
The findings indicate that polymorphisms of HDC gene were significantly associated with breast cancer in Chinese Han population and may be novel diagnostic or therapeutic targets for breast cancer.
HDC rs17740607 polymorphism is at least a partial loss-of-function variant and acts as a protective factor against chronic heart failure
Investigated variation across the HDC (histidine decarboxylase) gene for association with Tourette Syndrome.
HDC production in the stomach is associated with bile acid exposure and its related transcriptional regulation network of FXR (zeige NR1H4 Antikörper), SHP (zeige LAMC1 Antikörper), and CDX1 (zeige CDX1 Antikörper).
Data indicate that histidine decarboxylase (HDC) is expressed by neutrophils.
Structural study reveals that Ser (zeige SIGLEC1 Antikörper)-354 determines substrate specificity on human histidine decarboxylase.
crystal of histidine decarboxylase belonged to space group C2, with unit-cell parameters a = 215.16, b = 112.72, c = 171.39 A, beta = 110.3 degrees
This gene encodes a member of the group II decarboxylase family and forms a homodimer that converts L-histidine to histamine in a pyridoxal phosphate dependent manner. Histamine regulates several physiologic processes, including neurotransmission, gastric acid secretion,inflamation, and smooth muscle tone.
, histidine decarboxylase
, histidine decarboxylase-like
, headcase protein homolog
, L-histidine decarboxylase