anti-Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Antikörper

Human Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Interaktionspartner

1. total flavone of Desmodium styracifolium inhibited HK-2 (zeige HK2 Antikörper) cell apoptosis and autophagy by regulating KIM-1 via p38/MAPK (zeige MAPK14 Antikörper) pathway.

2. Polymorphism +4259A>C in exon 3 of the TIM-3 (zeige HAVCR2 Antikörper) gene is associated with susceptibility to multiple sclerosis but polymorphism -1637C>T in the promoter region of TIM-1 (zeige ARHGEF5 Antikörper) is not.

3. High KIM1 expression is associated with decreased proximal tubular epithelial cell function.

4. findings show that TIM1 (zeige ARHGEF5 Antikörper) is not an essential cellular receptor for hepatitis A virus entry into cultured cells

5. Urinary excretion of KIM-1 correlates with blood lead levels better than other traditional renal injury biomarkers, including N-acetyl-beta-(D)-glucosaminidase, alpha1-microglobulin, and beta2-microglobulin.

6. promising results were obtained for circulating KIM-1 prediction of renal outcomes in type 1 diabetes--{REVIEW}

7. data show that in addition to the phospholipid-binding function of HAVCR1, the enhancement of HCV infection involves other determinants in the IgV domain of HAVCR1. These findings expand the repertoire of molecules that HCV uses for cell entry, adding to the already complex mechanism of HCV infection and pathogenesis.

8. Review/Meta-analysis: suggest that TIM-1 (zeige ARHGEF5 Antikörper)-416G[C single nucleotide polymorphism is associated with the risk of asthma for the Asian ethnicity in the codominant (G/G vs. G/C) and dominant (G/G vs. G/C + C/C) genetic models.

9. Urinary NGAL (zeige LCN2 Antikörper) is a good predictor of mortality in established pediatric acute kidney injury (AKI) of heterogeneous etiology and outperforms calprotectin (zeige S100A8 Antikörper) and KIM-1. Urinary calprotectin (zeige S100A8 Antikörper) and KIM-1 predict renal replacement therapy requirement in pediatric AKI.

10. A panel consisting of IGFBP1 (zeige IGFBPI Antikörper), KIM1, GCLC (zeige GCLC Antikörper) and GSTM1 (zeige GSTM1 Antikörper) genes could be used in combination for early screening of CKDu, whereas these genes in addition with FN1 (zeige FN1 Antikörper), IGFBP3 (zeige IGFBP3 Antikörper) and KLK1 (zeige KLK1 Antikörper) could be used to monitor progression of CKDu. The regulation of these genes has to be studied on larger populations to validate their efficiency for further clinical use.

Chimpanzee Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Interaktionspartner

1. Data suggest that T-cell immunoglobulin domain and mucin (zeige SLC13A2 Antikörper) domain containing protein 1 (TIM1 (zeige TIMELESS Antikörper)) to be under positive natural selection in primates.

Rhesus Monkey Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Interaktionspartner

1. Data suggest that T-cell immunoglobulin domain and mucin (zeige SLC13A2 Antikörper) domain containing protein 1 (TIM1 (zeige TIMELESS Antikörper)) to be under positive natural selection in primates.

Mouse (Murine) Hepatitis A Virus Cellular Receptor 1 (HAVCR1) Interaktionspartner

1. findings show that TIM1 (zeige ARHGEF5 Antikörper) is not required for hepatitis A virus (HAV) replication and pathogenesis in permissive strains of mice, although it may facilitate early stages of infection by binding phosphatidylserine on the quasi-enveloped HAV surface

2. the interaction of TIM4TIM1 was found to promote Th2cell proliferation through enhancing SIRT1 (zeige SIRT1 Antikörper) expression in mice with nasal allergic rhinitis.

3. findings provide evidence for the role of Tim-1 in the induction of a cytokine storm phenomenon and the pathogenesis of Ebola virus disease

4. Cisplatin enhances kidney injury molecule-1 (Kim-1) gene expression in kidney S3 cells.

5. By preventing ERK1/2 phosphorylation following renal injury, STAT3 (zeige STAT3 Antikörper) phosphorylation is decreased, leading to less phosphorylated STAT3 (zeige STAT3 Antikörper) within the nucleus, and subsequently less KIM-1 mRNA increases post injury

6. Study used a previously described highly mobile membrane mimetic membrane in combination with a conventional lipid bilayer model to generate a membrane-bound configuration of Tim1 (zeige ARHGEF5 Antikörper) in silico, identified two possible states for a membrane-bound form of Tim1 (zeige ARHGEF5 Antikörper).

7. Our data reveal a previously unknown role for Galpha12 (zeige GNA12 Antikörper) in regulating efferocytosis and that renal tubular epithelial cells require KIM-1 to mediate this process.

8. Urinary L-FABP (zeige FABP1 Antikörper), NGAL (zeige LCN2 Antikörper), Kim-1 and albumin (zeige ALB Antikörper) levels increased during the acute phase of kidney injury and were significantly correlated with the degree of tubulointerstitial fibrosis during the chronic phase. These markers could detect higher risk of progression to CKD.

9. Blockade of Tim-1 changes Th1 (zeige HAND1 Antikörper)/Th2 balance and reduces circulating regulatory T cells to enhance atherosclerosis in LDL receptor (zeige LDLR Antikörper) knockout mice.

10. Our results suggest that KIM-1 is an endogenous protective mechanism against renal ischemia-reperfusion injury