HLA Class II DO alpha Proteine (HLA-DOA)

HLA-DOA belongs to the HLA class II alpha chain paralogues. Zusätzlich bieten wir Ihnen HLA-DOA Antikörper (35) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
HLA-DOA 3111 P06340
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
$6,869.04
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Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
$400.00
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Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 11 bis 12 Tage
$338.33
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HLA-DOA Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,

Weitere Proteine zu HLA Class II DO alpha (HLA-DOA) Interaktionspartnern

Human HLA Class II DO alpha (HLA-DOA) Interaktionspartner

  1. Contribution of a Non-classical HLA Gene, HLA-DOA, to the Risk of Rheumatoid Arthritis

  2. significant association was found between white wine liking and rs9276975:C>T polymorphism in the HLA-DOA gene.

  3. TAP2 (zeige TAP2 Proteine), HLA-DOA, HLA-DOB (zeige HLA-DOB Proteine), and tapasin (zeige TAPBP Proteine) loci are novel candidate regions for susceptibility to HCV infection and viral clearance in the Chinese population

  4. HLA-DO regulates surface presentation of human leukocyte antigen class II (zeige HLA-DRB5 Proteine)-restricted antigens on B cell malignancies.

  5. HLA-DOA, HLA-DRA, and HLA-DQA1 associated with spontaneous autoimmunity

  6. HLA-DOA mutations were analyzed for association with autoimmune diseases and B-cell leukemias.

  7. In transgenic mice expressing human HLA-DOA & HLA-DOB from a DC-specific promoter, as DO increased, A(b)-CLIP increased & class II-peptides decreased. DO impaired H-2M function, causing Ag-specific downmodulation of class II Ag processing/presentation.

  8. four novel HLA-DOA alleles, DOA*010106, DOA*0102, DOA*0103, and DOA*0104N, were identified by sequence-based typing

  9. minor allele of the SNP rs9296068 is significantly associated with liver transplantation rejection and with enhanced B-lymphocyte (zeige AKAP17A Proteine) participation in rejection, likely because of a dysfunctional HLA-DOA gene product.

  10. HLA-DOA polymorphisms are associated with Diabetes Mellitus, Type 1.

HLA-DOA Protein Überblick

Protein Überblick

HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level.

Genbezeichner und Symbole assoziert mit HLA-DOA

  • major histocompatibility complex, class II, DO alpha (HLA-DOA)
  • HLA-DNA Protein
  • HLA-DZA Protein
  • HLADZ Protein

Bezeichner auf Proteinebene für HLA-DOA

HLA class II histocompatibility antigen, DO alpha chain , HLA-D0-alpha , MHC DN-alpha , MHC DZ alpha , MHC class II antigen DOA , lymphocyte antigen , major histocompatibility complex, class II, DN alpha

GENE ID SPEZIES
3111 Homo sapiens
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