Glycoprotein M6A Proteine (GPM6A)

GPM6A encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. Zusätzlich bieten wir Ihnen Glycoprotein M6A Antikörper (86) und Glycoprotein M6A Kits (2) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
GPM6A 2823 P51674
GPM6A 234267 P35802
Ratte GPM6A GPM6A 306439 Q812E9
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage

GPM6A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine)

Weitere Proteine zu Glycoprotein M6A (GPM6A) Interaktionspartnern

Human Glycoprotein M6A (GPM6A) Interaktionspartner

  1. HDAC5 (zeige HDAC5 Proteine) emerges as a cellular conductor of MEF2C (zeige MEF2C Proteine) and M6a activity and is regulated by miR (zeige MLXIP Proteine)-124 and miR (zeige MLXIP Proteine)-9 to control neurite development.

  2. findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype

  3. Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B (zeige GPM6B Proteine) may act as novel oncogenes in the development of lymphoid leukemia.

  4. loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia

  5. Results indicate that M6a modulates mu-opioid receptor (zeige OPRM1 Proteine) endocytosis and post-endocytotic sorting and has an important role in receptor regulation.

  6. Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells.

Mouse (Murine) Glycoprotein M6A (GPM6A) Interaktionspartner

  1. GPM6a induces the clustering of lipid rafts and acts as a signal transducer that responds to extracellular signals.

  2. This study demonistrated that M6a is essential for the support of neurite extension in developmental brain.

  3. analysis of actin-independent behavior and membrane deformation exhibited by the four-transmembrane protein M6a

  4. M6a-deficient axons grow actively but are not growth suppressed by antibodies bound to four-transmembrane actin-based glycoprotein M6a concentrated on the edge of the axon growth cone.

  5. expression of shRNA against GPM6A markedly reduced the expression of neuroectodermal-associated genes (OTX1, Lmx1b (zeige LMX1B Proteine), En1 (zeige EN1 Proteine), Pax2 (zeige PAX2 Proteine), Pax5 (zeige PAX5 Proteine), Sox1 (zeige SOX1 Proteine), Sox2 (zeige SOX2 Proteine), and Wnt1 (zeige WNT1 Proteine)), and also the number of neural stem cells (NSC) derived from D3mshM6A cells

  6. These results suggest that M6a plays a role in retinal development by regulating neurites, and it may also function to modulate synaptic activities in the adult retina.

Glycoprotein M6A (GPM6A) Protein Überblick

Protein Überblick

This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.

Genbezeichner und Symbole assoziert mit Glycoprotein M6A Proteine (GPM6A)

  • glycoprotein M6A (GPM6A)
  • glycoprotein m6a (Gpm6a)
  • glycoprotein M6A (gpm6a)
  • glycoprotein M6A (Gpm6a)
  • glycoprotein M6A L homeolog (gpm6a.L)
  • DMbeta/M6a Protein
  • EMA Protein
  • Gpm6 Protein
  • gpm6a Protein
  • gpm6a-A Protein
  • M6a Protein
  • MGC145278 Protein

Bezeichner auf Proteinebene für Glycoprotein M6A Proteine (GPM6A)

neuronal membrane glycoprotein M6-a , neuronal proteolipid GPM6A , M6a , glycoprotein M6A , glycoprotein M6A L homeolog , glycoprotein M6A, myelin PLP-related membrane protein DM beta

2823 Homo sapiens
234267 Mus musculus
306439 Rattus norvegicus
422569 Gallus gallus
475641 Canis lupus familiaris
507389 Bos taurus
698488 Macaca mulatta
742345 Pan troglodytes
780312 Xenopus (Silurana) tropicalis
100172611 Pongo abelii
100229820 Taeniopygia guttata
100359107 Oryctolagus cuniculus
100725735 Cavia porcellus
394384 Xenopus laevis
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