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GPM6A encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. Zusätzlich bieten wir Ihnen Glycoprotein M6A Antikörper (99) und Glycoprotein M6A Kits (4) und viele weitere Produktgruppen zu diesem Protein an.
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HDAC5 (zeige HDAC5 Proteine) emerges as a cellular conductor of MEF2C (zeige MEF2C Proteine) and M6a activity and is regulated by miR (zeige MLXIP Proteine)-124 and miR (zeige MLXIP Proteine)-9 to control neurite development.
findings thus indicate a critical role of correct GPM6A/M6 levels for cognitive function and support a role of the GPM6A duplication for the patient's phenotype
Data indicate that neuronal membrane glycoproteins GPM6A and GPM6B (zeige GPM6B Proteine) may act as novel oncogenes in the development of lymphoid leukemia.
loosing dynamic regulation of neuronal GPM6A expression poses a genetic risk for claustrophobia
Results indicate that M6a modulates mu-opioid receptor (zeige OPRM1 Proteine) endocytosis and post-endocytotic sorting and has an important role in receptor regulation.
Results suggest that expression level of GPM6A is associated with the differentiation and neuronal migration of neurons derived from undifferentiated human embryonic stem cells.
GPM6a induces the clustering of lipid rafts and acts as a signal transducer that responds to extracellular signals.
This study demonistrated that M6a is essential for the support of neurite extension in developmental brain.
analysis of actin-independent behavior and membrane deformation exhibited by the four-transmembrane protein M6a
M6a-deficient axons grow actively but are not growth suppressed by antibodies bound to four-transmembrane actin-based glycoprotein M6a concentrated on the edge of the axon growth cone.
expression of shRNA against GPM6A markedly reduced the expression of neuroectodermal-associated genes (OTX1, Lmx1b (zeige LMX1B Proteine), En1 (zeige EN1 Proteine), Pax2 (zeige PAX2 Proteine), Pax5 (zeige PAX5 Proteine), Sox1 (zeige SOX1 Proteine), Sox2 (zeige SOX2 Proteine), and Wnt1 (zeige WNT1 Proteine)), and also the number of neural stem cells (NSC) derived from D3mshM6A cells
These results suggest that M6a plays a role in retinal development by regulating neurites, and it may also function to modulate synaptic activities in the adult retina.
This gene encodes the 70 kDa subunit of MT-A which is part of N6-adenosine-methyltransferase. This enzyme is involved in the posttranscriptional methylation of internal adenosine residues in eukaryotic mRNAs, forming N6-methyladenosine.
neuronal membrane glycoprotein M6-a
, neuronal proteolipid GPM6A
, glycoprotein M6A
, glycoprotein M6A L homeolog
, glycoprotein M6A, myelin PLP-related membrane protein DM beta