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GST encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification.
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Li, Wang, Zhang, Le, Li: Glutathione-mediated detoxification of halobenzoquinone drinking water disinfection byproducts in T24 cells. in Toxicological sciences : an official journal of the Society of Toxicology 2014
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Rodríguez-Ramiro, Ramos, Bravo, Goya, Martín: Procyanidin B2 induces Nrf2 translocation and glutathione S-transferase P1 expression via ERKs and p38-MAPK pathways and protect human colonic cells against oxidative stress. in European journal of nutrition 2011
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we confirmed several existing chemoinformatic filters and more importantly extended them as well as added novel filters that specify compounds with anti-GST/GSH activity. Selected compounds were also tested using different antibody-based GST detection technologies and exhibited no interference clearly demonstrating specificity toward their GST/GSH interaction.
Our findings indicate that the medical staff exposed to low IR levels were under risk of significant oxidative stress that was enhanced by their glutathione S-transferase (GST (zeige GSTA1 ELISA Kits)) polymorphisms.
GSTK1 T/T genotype may be a novel risk factor for the prediction of overweight status in SCZ male patients.
High glutathione-S-transferase (zeige GSTa2 ELISA Kits) is associated with type 2 diabetes mellitus.
DsbA-L is localized in both the mitochondria and the endoplasmic reticulum (ER) in adipocytes; its ER localization plays a critical role in suppressing ER stress and promoting adiponectin biosynthesis and secretion.
we have optimized the GST-Nck1-SH2 pull-down procedure to obtain tyrosine-phosphorylated proteins in tumor tissues
This study does not give evidence of interaction between the GST polymorphisms and smoking may although this study provided sufficient statistical power to detect modest interaction.
SNP-1308G/T (rs1917760) genotypes of DsbA-L (zeige GSTK1 ELISA Kits) gene might participate in insulin (zeige INS ELISA Kits) secretion and body fat distribution. It is possible that polymorphisms of DsbA-L (zeige GSTK1 ELISA Kits) gene associated with metabolic diseases[DsbA-L (zeige GSTK1 ELISA Kits)]
structure and function characterization of a GST from human breast
Presence of hGSTK1 in both peroxisomes and mitochondria. The C-terminus of hGSTK1 is essential for localization of the protein to peroxisomes, and the C-terminal sequence Ala-Arg-Leu represents a peroxisome targeting signal 1 (PTS1).
identification of the promoter region and a comprehensive examination of tissue expression of MGST1 (zeige MGST1 ELISA Kits)
MGST1 is a dominant, highly expressed enzyme in mouse retinal pigment epithelium (RPE) microsomes that displays an important protective function against oxidative insult in the RPE that decreases with age.
Gst genes are extensively downregulated in primary but not metastatic TRAMP (zeige DPT ELISA Kits) tumors.
This gene encodes a member of the kappa class of the glutathione transferase superfamily of enzymes that function in cellular detoxification. The encoded protein is localized to the peroxisome and catalyzes the conjugation of glutathione to a wide range of hydrophobic substates facilitating the removal of these compounds from cells. Alternative splicing results in multiple transcript variants.
, glutathione S-transferase k1
, glutathione S-transferase subunit 13 homolog
, microsomal GST-1
, microsomal GST-I
, GST class-sigma
, glutathione S-transferase
, glutathione-dependent PGD synthase
, glutathione-dependent PGD synthetase
, glutathione-requiring prostaglandin D synthase
, prostaglandin D2 synthase 2, hematopoietic
, prostaglandin-H2 D-isomerase