anti-Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Antikörper

GCNT1 is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. Zusätzlich bieten wir Ihnen GCNT1 Kits (14) und GCNT1 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GCNT1 2650 Q02742
GCNT1 14537 Q09324
GCNT1 64043  
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Top anti-GCNT1 Antikörper auf antikoerper-online.de

Showing 10 out of 70 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB 0.4 mL 6 bis 8 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Antibody is used in Western blot to detect GCNT1 in mouse kidney tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert WB Western blot analysis in T47D cell line lysates (35ug/lane). 400 μL 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of anti-GCNT1 Antibody in CEM cell line lysates (35ug/lane) Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. BC = breast carcinoma; HC = hepatocarcinoma. 400 μL 2 bis 3 Tage
$515.63
Details
Human Maus Unkonjugiert WB Western Blot analysis of GCNT1 expression in transfected 293T cell line by GCNT1 MaxPab polyclonal antibody.Lane1:GCNT1 transfected lysate(47.08 KDa).Lane2:Non-transfected lysate. 50 μg 11 bis 12 Tage
$364.00
Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemical staining (Formalin-fixed paraffin-embedded sections) of human duodenum with GCNT1 polyclonal antibody  shows strong cytoplasmic positivity in glandular cells. 100 μL 11 bis 12 Tage
$637.32
Details
Human Kaninchen Unkonjugiert WB Western Blot analysis of GCNT1 expression in transfected 293T cell line by GCNT1 MaxPab polyclonal antibody.Lane 1: GCNT1 transfected lysate(49.80 KDa).Lane 2: Non-transfected lysate. GCNT1 MaxPab rabbit polyclonal antibody. Western Blot analysis of GCNT1 expression in human pancreas. 100 μg 11 bis 12 Tage
$350.67
Details
Human Kaninchen Unkonjugiert WB Western blot analysis of extracts of various cell lines, using GCNT1 antibody (ABIN4903747) at 1:1000 dilution. Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates/proteins: 25ug per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Basic Kit. Exposure time: 30s. 100 μL 11 bis 13 Tage
$366.77
Details
Human Kaninchen Unkonjugiert ELISA, WB   200 μL 11 bis 16 Tage
$658.43
Details

Am meisten referenzierte anti-GCNT1 Antikörper

  1. Human Polyclonal GCNT1 Primary Antibody für WB - ABIN515997 : Petrosyan, Cheng: Golgi fragmentation induced by heat shock or inhibition of heat shock proteins is mediated by non-muscle myosin IIA via its interaction with glycosyltransferases. in Cell stress & chaperones 2014 (PubMed)

Weitere Antikörper gegen GCNT1 Interaktionspartner

Human Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Interaktionspartner

  1. GCNT1 expression in prostate biopsy specimen is a significant and independent predictor of recurrence after radical prostatectomy, which can be used in pre-treatment decision making for the patient.

  2. GCNT1 expression in prostate cancer positively correlates with cancer progression and prostate-specific antigen recurrence.

  3. Results show that ST3Gal1 uses GM130-GRASP65 and giantin, whereas C2GnT-L uses only giantin for Golgi targeting and defective giantin dimerization in PC-3 and DU145 prostate cancer cells causes fragmentation of the Golgi and prevents its targeting.

  4. NMIIA is the master regulator of Golgi fragmentation induced by heat shock or inhibition/depletion of HSP70/90 through interaction with gylosyltransferases.

  5. GCNT1 is over-expressed in prostate cancer and is associated with higher levels of core 2 O-sLe(x) in PSA, PAP and MUC1 proteins.

  6. Immunohistochemical expression of core 2 beta1,6-N-acetylglucosaminyl transferase 1 (C2GnT1) in endometrioid-type endometrial carcinoma may be a novel potential prognostic factor.

  7. C2GnT-expressing prostate cancer cells evade NK cell immunity and survive longer in the host blood circulation, thereby resulting in the promotion of prostate cancer metastasis.

  8. GOLPH3 can regulate cell-cell interaction by controlling Golgi retention of C2GnT1.

  9. Down-regulation of C2GnT1 is correlated with breast cancer

  10. The X-ray crystal structure (2.3 A resolution) of a mutant form of C2GnT-L (C217S) in complex with UDP was solved. C2GnT-L exists in an "open" conformation and a "closed" conformation.

  11. In C2GnT-expressing bladder tumour cells galectin-3 bound the NKG2D-binding site of MICA, reducing the affinity of MICA for NKG2D on natural killer cells and hence severely impairing natural killer cell activation.

  12. Data show that the reconstituted membrane system in cells expressing C2GnT-I led to the lipid vesicles exhibiting an enzyme activity 11 times higher than that found in microsomal membranes.

  13. Core2 O-glycan structure is essential for expression of SI and DDP-IV during intestinal cell differentiation.

  14. Overexpression of C2GnT-1 enhances the metastatic potential of testicular germ cell tumor.

  15. EGF suppressed C2GnT activity in a time- and dose-dependent fashion, and also suppressed core 4 beta1,6 N-acetylglucosaminyltransferase (C4GnT) activity

  16. presence of multiple tissue-specific promoters for the C2GnT I gene

  17. elevated glucose increases the activity of core 2 GlcNAc-T and adhesion of human leukocytes to retinal capillary endothelial cells, in a dose-dependent manner, through diabetes-activated serine/threonine protein kinase C beta2-dependent phosphorylation

  18. core 2 beta1-6-N-glucosaminyltransferase and dimerization of P-selectin glycoprotein ligand-1 have roles in rolling on P-selectin

  19. C2GnT-1 regulates sLeX expression level during differentiation of pre-B cells

  20. upregulated by all-trans retinoic acid (RA) and by IL-4 and IL-13 in the H292 airway epithelial cell line

Mouse (Murine) Glucosaminyl (N-Acetyl) Transferase 1, Core 2 (GCNT1) Interaktionspartner

  1. we show that Gcnt1 transcription and subsequent P-lselectin ligand induction in Th1 cells is governed by binding of STAT4 and T-bet to a distal enhancer and further regulated by epigenetic marks such as H3K27me3.

  2. simultaneous deletion of the Core2 beta1,6-N-acetylglucosaminyltransferase (C2GnT) enzymes C2GnT1 and C2Gnt2 resulted in delayed expulsion of worms.

  3. striking differences between the requirement of FucT-VII and C2GlcNAcT-I for Ligands for E-selectin and P-selectin expression in CD4+ T cells.

  4. Core2 O-glycan structure is essential for expression of SI and DDP-IV during intestinal cell differentiation.

  5. plays a critical role in lymphocyte trafficking during chronic inflammation

  6. Distinct functions for C2GlcNAcT-I in the differential elaboration of endothelial venule glycoproteins that set a threshold for the amount of L-selectin needed for lymphocyte homing.

  7. data demonstrate that multiple C2GlcNAcT enzymes can contribute to P-selectin ligand formation and may cooperate with C2GlcNAcT-I in the control of CD8 T cell trafficking

  8. IGnT deficient mice had reduced spontaneous locomotive activity, and the number of peripheral blood lymphocytes was also reduced and renal function decreased in the deficient mice

  9. Data report the x-ray crystal structures of murine core 2 O-glycan (Galbeta1-3[GlcNAcbeta1-6]GalNAc-O-Ser/Thr) (C2GnT-L) in the absence and presence of the acceptor substrate Galbeta1-3GalNAc at 2.0 and 2.7A resolution, respectively.

  10. These results suggest that the core 2 GlcNAc extended glycan chains on megalin can change the ligand-binding affinity and capacity.

  11. Pancreas carcinoma antigen, C2GnT, fused to invariant chain elicits T-cell response and tumor growth inhibition.

  12. Core2 1-6-N-glucosaminyltransferase-I is crucial for the formation of atherosclerotic lesions in apolipoprotein E-deficient mice.

  13. Core2 1-6-N-glucosaminyltransferase-I deficiency protects injured arteries from neointima formation in ApoE-deficient mice

GCNT1 Antigen-Profil

Protein Überblick

This gene is a member of the beta-1,6-N-acetylglucosaminyltransferase gene family. It is essential to the formation of Gal beta 1-3(GlcNAc beta 1-6)GalNAc structures and the core 2 O-glycan branch. The gene coding this enzyme was originally mapped to 9q21, but was later localized to 9q13. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Genbezeichner und Symbole assoziert mit GCNT1

  • glucosaminyl (N-acetyl) transferase 1, core 2 L homeolog (gcnt1.L) Antikörper
  • glucosaminyl (N-acetyl) transferase 1, core 2 (GCNT1) Antikörper
  • glucosaminyl (N-acetyl) transferase 1, core 2 (Gcnt1) Antikörper
  • 5630400D21Rik Antikörper
  • B130048E03 Antikörper
  • C2 GlcNAcT Antikörper
  • C2GNT Antikörper
  • C2GNT-L Antikörper
  • C2GNT1 Antikörper
  • core 2 GlcNAc-T Antikörper
  • G6NT Antikörper
  • IGnT Antikörper
  • NACGT2 Antikörper
  • NAGCT2 Antikörper

Bezeichner auf Proteinebene für GCNT1

enzymatic glycosylation-regulating , glucosaminyl (N-acetyl) transferase 1, core 2 (beta-1,6-N-acetylglucosaminyltransferase) , Beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , glucosaminyl (N-acetyl) transferase 1, core 2 , glucosaminyl transferase 1, core 2 , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase-like , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N--acetylglucosaminyltransferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase , beta-1,6-N-acetylglucosaminyltransferase , core 2 GnT , core 2 beta-1,6-N-acetylglucosaminyltransferase I , core 2 beta1,6 N-acetylglucosaminyltransferase-I , core 2 branching enzyme , core 2-branching enzyme , core2-GlcNAc-transferase , beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT) , C2GNT , core 2 GNT , beta1,6 N-acetylglucosaminyltransferase

GENE ID SPEZIES
380501 Xenopus laevis
427260 Gallus gallus
704639 Macaca mulatta
100011966 Monodelphis domestica
100347030 Oryctolagus cuniculus
100397450 Callithrix jacchus
100453351 Pongo abelii
100481771 Ailuropoda melanoleuca
100590764 Nomascus leucogenys
2650 Homo sapiens
14537 Mus musculus
281778 Bos taurus
484158 Canis lupus familiaris
64043 Rattus norvegicus
101121316 Ovis aries
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