General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) ELISA Kits

may act as a muscle specific transcription factor\; human homolog may be associated with the Williams-Beuren microdeletion syndrome [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen GTF2IRD1 Antikörper (97) und GTF2IRD1 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GTF2IRD1 246770  
GTF2IRD1 57080 Q9JI57
GTF2IRD1 9569 Q9UHL9
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Top GTF2IRD1 ELISA Kits auf antikoerper-online.de

Showing 3 out of 5 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
$495.00
Details
Maus < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
$810.17
Details

Weitere ELISA Kits für GTF2IRD1 Interaktionspartner

Cow (Bovine) General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Interaktionspartner

  1. cGMP-dependent protein kinase Ibeta binds to TFII-I and IRAG through a common interaction motif

Mouse (Murine) General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Interaktionspartner

  1. GTF2IRD1 represses the transcription of transforming growth factor beta-dependent pro-fibrosis genes by recruiting PRDM16 and EHMT1 onto their promoter/enhancer regions.

  2. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.

  3. the absence of GTF2IRD1 is associated with increased expression of genes involved in cellular proliferation, including growth factors consistent with the observed phenotype of extreme thickening of the epidermis.

  4. Gtf2ird1 is essential for Mkx transcription, while also linking mechanical forces to Mkx-mediated tendon homeostasis and regeneration.

  5. Gtf2ird1 is expressed in a number of cell types within the cochlea. Gtf2ird1 null mice showed higher auditory thresholds.

  6. findings suggest an important role for GTF2IRD1 in regulating the level and topology of rod and cone gene expression, and in maintaining normal retinal function.

  7. GTF2IRD2 has evolved as a regulator of GTF2IRD1 and TFII-I; inhibiting their function by direct interaction and sequestration into inactive nuclear zones.

  8. This study presented that role for GTF2IRD1 in the motoric and anxiety-related abnormalities seen in Williams-Beuren syndrome, and suggests basal ganglia and potentially cerebellar abnormalities in Gtf2ird1 mice.

  9. Widespread and robust expression of Gtf2ird1 protein in the developing rodent brain, is reported.

  10. Data show the existence of a negative autoregulatory mechanism that controls the level of GTF2IRD1 transcription via direct binding of the GTF2IRD1 protein to a highly conserved region of the GTF2IRD1 promoter containing an array of three binding sites.

  11. The presence of different domains in 11 alternatively spliced isoforms of Gtf2ird1 indicates that the activity exerted by this molecule influences multiple promoters active in mouse skeletal muscle.

  12. TFII-I (Mus-TRD1) has a role in regulating immunoglobulin promoter activity

  13. First systematic and unbiased analysis of individual GTF2I-like repeats with regard to DNA binding

  14. GTF2IRD1 is a genetic determinant of mammalian craniofacial and cognitive development

  15. During development, a dynamic pattern of GTF2IRD1 expression is found predominantly in musculoskeletal tissues, the pituitary, craniofacial tissues, the eyes and tooth buds.

  16. GTF2IRD1 knockout mice showed a reduced size of the corpus callosum

  17. These transcription factors may influence fear and social behavior through the alteration of neurochemical pathways

  18. expression of TFII-I gene family were mapped in embryonic tooth germs; at bud stage, Gtf2ird1 & Gtf2ird2 were expressed in epithelial buds; at early bell stage, expression of Gtf2ird1 & Gtf2ird2 was observed in preameloblasts & preodontoblasts

  19. analysis of the consensus binding site for TFII-I family member BEN

  20. homozygous loss of Gtf2ird1 or Gtf2i results in multiple phenotypic manifestations, including embryonic lethality; brain hemorrhage; and vasculogenic, craniofacial, and neural tube defects; defects in yolk sac vasculogenesis and angiogenesis

Human General Transcription Factor II I Repeat Domain-Containing 1 (GTF2IRD1) Interaktionspartner

  1. Among 110 SNPs within the 7q11.23 William's Syndrome (WS) chromosomal region, we found one associated locus located at GTF2IRD1, which has been implicated in animal models of WS.

  2. The mis-regulation of genes downstream of GTF2IRD1, including TbetaR2 and BMPR1b, also individually promoted mammary cancer development, and silencing of TbetaR2 suppressed GTF2IRD1-driven tumor promotion.

  3. Study demonstrates a significant association between SLE in Chinese Han population and the GTF2I rs117026326 T allele/GTF2IRD1 rs4717901 C allele.

  4. GTF2IRD1 binding partners are mostly involved in chromatin modification and transcriptional regulation, whilst others indicate an unexpected role in connection with the primary cilium.

  5. GTF2IRD1 is SUMOylated by the SUMO E2 ligase UBC9 and the level of SUMOylation is enhanced by PIASxbeta.

  6. CLIP2 haploinsufficiency by itself does not lead to the physical or cognitive characteristics of the Williams-Beuren syndrome; GTF2IRD1 and GTF2I are the main genes causing the cognitive defects

  7. This study provided evidences that insufficiency of GTF2IRD1 protein contributes to abnormalities of facial development, motor function and specific behavioural disorders that accompany Williams-Beuren syndrome.

  8. functional hemizygosity for the GTF2I and GTF2IRD1 genes is the main cause of the neurocognitive profile and some aspects of the gestalt phenotype of Williams-Beuren syndrome

  9. Data show the existence of a negative autoregulatory mechanism that controls the level of GTF2IRD1 transcription via direct binding of the GTF2IRD1 protein to a highly conserved region of the GTF2IRD1 promoter containing an array of three binding sites.

  10. characterization and involvement in slow muscle-specific gene expression

  11. role as a repressor of slow fiber-specific transcription through mechanisms involving direct interactions with MEF2C and the nuclear receptor co-repressor

  12. GTF2IRD1 and GTF2I have roles in causing deficits on visual spatial functioning

  13. human VEGFR-2 promoter is functionally counter-regulated by TFII-I and TFII-IRD1.

  14. GTF2IRD1 is a genetic determinant of mammalian craniofacial and cognitive development

  15. a regulator of slow fiber-specific genes

  16. functional analysis of human GTF2IRD1 in regulation of three genes (HOXC8, GOOSECOID and TROPONIN I)

  17. analysis of the consensus binding site for TFII-I family member BEN

  18. GTF2IRD1 is associated with Williams syndrome facies and visual-spatial construction.

GTF2IRD1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene contains five GTF2I-like repeats and each repeat possesses a potential helix-loop-helix (HLH) motif. It may have the ability to interact with other HLH-proteins and function as a transcription factor or as a positive transcriptional regulator under the control of Retinoblastoma protein. This gene plays a role in craniofacial and cognitive development and mutations have been associated with Williams-Beuren syndrome, a multisystem developmental disorder caused by deletion of multiple genes at 7q11.23. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit GTF2IRD1

  • GTF2I repeat domain containing 1 (GTF2IRD1) Antikörper
  • GTF2I repeat domain containing 1 (Gtf2ird1) Antikörper
  • general transcription factor II I repeat domain-containing 1 (Gtf2ird1) Antikörper
  • GTF2I repeat domain containing 1 (gtf2ird1) Antikörper
  • general transcription factor II-I repeat domain-containing protein 1 (LOC100461122) Antikörper
  • GTF2I repeat domain containing 1 S homeolog (gtf2ird1.S) Antikörper
  • 1700012P16Rik Antikörper
  • BEN Antikörper
  • cream1 Antikörper
  • ESTM9 Antikörper
  • Gtf2il Antikörper
  • GTF2IRD1 Antikörper
  • gtf3 Antikörper
  • hMusTRD1alpha1 Antikörper
  • mustrd1 Antikörper
  • rbap2 Antikörper
  • Tg(Alb1-Myc)166.8Sst Antikörper
  • wbs Antikörper
  • wbscr11 Antikörper
  • wbscr12 Antikörper
  • X83320 Antikörper
  • XBEN Antikörper
  • XWBSCR11 Antikörper

Bezeichner auf Proteinebene für GTF2IRD1

general transcription factor II-I repeat domain-containing protein 1 , general transcription factor II I repeat domain-containing 1 , Alb-c-myc line 166.8 , Alb/c-myc line 166.8 , GTF2I repeat domain-containing 1 , GTF2I repeat domain-containing protein 1 , Williams-Beuren syndrome chromosome region 11 , binding factor for early enhancer , c-myc line 166.8 , general transcription factor 3 , muscle TFII-I repeat domain-containing protein 1 , transcription factor GTF3 alpha 2 , transcription factor GTF3 gamma 2 , GTF2I repeat domain containing 1 , USE B1-binding protein , general transcription factor III , muscle TFII-I repeat domain-containing protein 1 alpha 1 , slow-muscle-fiber enhancer-binding protein , williams-Beuren syndrome chromosomal region 12 protein , general transcription factor II-I repeat domain-containing protein 1-like , Binding factor for early enhancer , Williams-Beuren syndrome critical region 11-like protein

GENE ID SPEZIES
507792 Bos taurus
246770 Rattus norvegicus
57080 Mus musculus
463471 Pan troglodytes
489796 Canis lupus familiaris
81597 Danio rerio
417487 Gallus gallus
693935 Macaca mulatta
9569 Homo sapiens
100461122 Pongo abelii
100473117 Ailuropoda melanoleuca
100510956 Sus scrofa
398320 Xenopus laevis
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