GRO alpha Protein Proteine (GRO-A)

GRO-A encodes a member of the CXC subfamily of chemokines.

alle Proteine anzeigen Gen GeneID UniProt
GRO-A 2919 P09341
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Top GRO alpha Protein Proteine auf

Showing 7 out of 8 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 11 Days
Escherichia coli (E. coli) Maus His tag 100 μg Anmelden zum Anzeigen 11 Days
Escherichia coli (E. coli) Human Unkonjugiert   25 μg Anmelden zum Anzeigen 9 bis 11 Tage
Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 11 bis 18 Tage
Escherichia coli (E. coli) Ratte Unkonjugiert   1 mg Anmelden zum Anzeigen 11 bis 16 Tage
Ratte Unkonjugiert   5 μg Anmelden zum Anzeigen 9 bis 10 Tage
Maus Unkonjugiert   5 μg Anmelden zum Anzeigen 9 bis 10 Tage

GRO-A Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat

Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu GRO alpha Protein (GRO-A) Interaktionspartnern

Human GRO alpha Protein (GRO-A) Interaktionspartner

  1. By inducing glycolysis, CXCL1 plays a crucial role in both cancer progression and metastasis in colorectal cancer patients.

  2. Adiponectin treatment of ovarian cancer cells induces angiogenesis via CXC chemokine ligand 1 independently of vascular endothelial growth factor. These findings suggest that adiponectin may serve as a novel therapeutic target for ovarian cancer.

  3. CXCL1 gene expression was associated with the negative syndrome in non-deficit schizophrenia patients, while no association in deficit schizophrenia was observed.

  4. GRO-alpha from OSF-associated fibroblasts paracrinally promotes oral malignant transformation and significantly contributes to OSCC development.

  5. Both GRO-alpha and IL-8 can activate TAK1/NFkappaB signaling via the CXCR2 receptor.

  6. Results show that the expression of CXCL1 and CXCL2 in tumor cells and tumor-infiltrated CD11b+ myeloid cells is critically involved in the promotion of the generation of monocytic myeloid-derived suppressor cells (mo-MDSC) from bone marrow cells. CXCL1 and CXCL2 were found to specifically promote the expansion of mo-MDSC rather than granulocytic MDSC (G-MDSC).

  7. The chemokine Gro1 induced in response to inflammation triggers senescence and arrests development of new neurons in the hippocampus and that the magnitude of this response is sex-dependent.

  8. CXCL1 displays a specific microRNA (miR) upregulated by the prototypical colon cancer onco-miR miR-105.

  9. These results show that AKIP1 is crucial in cervical cancer angiogenesis and growth by elevating the levels of the NF-kappaB-dependent chemokines CXCL1, CXCL2, and CXCL8.

  10. Adipose stromal cells recruitment to tumours, driven by CXCL1 and CXCL8, promotes prostate cancer progression.

  11. CXCL1, which is produced by breast cancer cells, can promote cancer growth and development

  12. miR-204 inhibits cell proliferation in gastric cancer by targeting CKS1B, CXCL1 and GPRC5A.

  13. Thrombocytosis was more prevalent in patients with inflammatory breast cancer (IBC)than in those with non-IBC and it was associated with poor prognosis. GRO and TGF-beta were associated with thrombocytosis in IBC

  14. the plasma concentrations of CXCL1 indicated the disease activity and prognosis in interstitial pneumonia with autoimmune features (IPAF). Thus, the CXCL1/CXCR2 axis appears to be involved in the progression of IPAF.

  15. CXCL1/8 secreted by adipose-derived mesenchymal stem cells could promote breast cancer angiogenesis.

  16. GROA overexpression is associated with invasion in triple negative breast cancer.

  17. The results of the transwell chemotaxis assay also supported the above results. Our data suggest that APN can promote h-JBMMSC chemotaxis by up-regulating CXCL1 and CXCL8

  18. This study highlighted CAF-secreted CXCL1 as an attractive target to reverse tumor radioresistance.

  19. we identified the microRNA miR-200a as a putative post-transcriptional regulator of CXCL1 in hepatocellular carcinoma

  20. study demonstrates that CXCL1 can transform NOFs into senescent CAFs via an autocrine mechanism

GRO alpha Protein (GRO-A) Protein Überblick

Protein Überblick

This gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signal through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.

Genbezeichner und Symbole assoziert mit GRO alpha Protein Proteine (GRO-A)

  • C-X-C motif chemokine ligand 1 (CXCL1)
  • FSP Protein
  • GRO1 Protein
  • GROa Protein
  • MGSA Protein
  • MGSA-a Protein
  • NAP-3 Protein
  • SCYB1 Protein

Bezeichner auf Proteinebene für GRO alpha Protein Proteine (GRO-A)

C-X-C motif chemokine 1 , GRO-alpha(1-73) , GRO1 oncogene (melanoma growth stimulating activity, alpha) , GRO1 oncogene (melanoma growth-stimulating activity) , MGSA alpha , fibroblast secretory protein , growth-regulated alpha protein , melanoma growth stimulatory activity alpha , neutrophil-activating protein 3

2919 Homo sapiens
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