anti-GM2 Ganglioside Activator (GM2A) Antikörper

GM2A encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Zusätzlich bieten wir Ihnen GM2 Ganglioside Activator Kits (17) und GM2 Ganglioside Activator Proteine (16) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GM2A 282838  
GM2A 2760 P17900
GM2A 14667 Q60648
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Top anti-GM2 Ganglioside Activator Antikörper auf antikoerper-online.de

Showing 10 out of 169 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Human Kaninchen Unkonjugiert WB WB Suggested Anti-GM2A Antibody Titration:  0.2-1 ug/ml  Positive Control:  HT1080 cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Meerschweinchen Kaninchen Unkonjugiert WB WB Suggested Anti-GM2A Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Hela cell lysate WB Suggested Anti-GM2A  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: Hela cell lysate 100 μL 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB   100 μg 6 bis 7 Tage
$429.84
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg 2 bis 3 Tage
$515.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Anti-GM2A antibody  ABIN1048677 IHC staining of human breast. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Anti-GM2A antibody  ABIN1048677 IHC staining of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert IHC, IHC (p) Human Kidney: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Skin: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg 11 bis 14 Tage
$484.00
Details
Human Kaninchen Unkonjugiert WB 100 μL 11 bis 14 Tage
$551.83
Details
Hund Ziege Unkonjugiert EIA, WB HEK293 lysate (10 µg protein in RIPA buffer) overexpressing Human GM2A with DYKDDDDK tag probed with AP23749PU-N (1.0 µg/ml) in Lane A and probed with anti- DYKDDDDK Tag (1/30000) in Lane C. Mock-transfected HEK293 probed with AP23749PU-N (1 mg/ml) in Lane B. Primary incubations were for 1 hour. Detected by chemiluminescence. Staining of Rat Kidney lysate using GM2A antibody at 0.3 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg 6 bis 8 Tage
$445.50
Details

Am meisten referenzierte anti-GM2 Ganglioside Activator Antikörper

  1. Human Polyclonal GM2A Primary Antibody für ELISA, WB - ABIN4315197 : Todeschini, Dos Santos, Handa, Hakomori: Ganglioside GM2-tetraspanin CD82 complex inhibits met and its cross-talk with integrins, providing a basis for control of cell motility through glycosynapse. in The Journal of biological chemistry 2007 (PubMed)

Weitere Antikörper gegen GM2 Ganglioside Activator Interaktionspartner

Human GM2 Ganglioside Activator (GM2A) Interaktionspartner

  1. Review of GM2A mutations causing GM2 activator protein deficiency and GM2 gangliosidosis-AB variant.

  2. Studies indicate that sphingolipid activator proteins (SAPs) and anionic lipids are essential stimulators to reach physiological rates of lysosomal sphingolipid degradation.

  3. this study has established the potential role of GM2A in breast cancer progression

  4. Mobilization of membrane lipids by GM2AP was also inhibited in the presence of cholesterol or SM, as revealed by surface plasmon resonance studies

  5. Gene polymorphisms of MD2 and GM2A were associated with the occurrence or severity of neonatal necrotizing enterocolitis.

  6. In vitro assays with the isolated H1 or H2 homodimers (beta-alpha hybrid construct of beta-hexosaminidase A subunits) confirmed that neither was capable of human GM2AP-dependent hydrolysis of GM2 ganglioside.

  7. impact of GM2AP on glucose metabolism

  8. Treatment of meniscal explants with IL-1RA inhibited the expression of many catabolic genes following a single bout of high dynamic strain.

  9. these results provide novel insights into the physiological functions of GM2AP in obesity.

  10. GM2 activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

  11. Two new structures of GM2-AP with bound lipids, showing two different lipid-binding modes within the apolar pocket

  12. elucidation of mode of action on gangioside GM2

  13. alpha-subunit loop structure is required for GM2 activator protein binding by beta-hexosaminidase A

  14. glycosphingolipids, particularly GM2, form a complex with CD82, and this complex interacts with Met and thereby inhibits HGF-induced Met tyrosine kinase activity, as well as integrin to Met cross-talk

Mouse (Murine) GM2 Ganglioside Activator (GM2A) Interaktionspartner

  1. The most interesting finding was the association of the GM2-AP with the acrosomal apparatus in early spermatids. A modest to intense staining was observed in some acrosomal granules and acrosomal caps. The GM2-AP seemed to disappear from acrosomal caps in the later stage of spermatids, in which the nucleus became elongated and condensed.

  2. impact of GM2AP on glucose metabolism

  3. these results provide novel insights into the physiological functions of GM2AP in obesity.

  4. GM2 activator protein exerts strong and broad inhibitory effects on the hydrolysis of phospholipids carried out by plant and microbial phospholipases D

  5. The trafficking of prosaposin and GM2 activator protein to the lysosome in sertoli cells is dependent on sortilin.

GM2 Ganglioside Activator (GM2A) Antigen-Profil

Protein Überblick

This gene encodes a small glycolipid transport protein which acts as a substrate specific co-factor for the lysosomal enzyme beta-hexosaminidase A. Beta-hexosaminidase A, together with GM2 ganglioside activator, catalyzes the degradation of the ganglioside GM2, and other molecules containing terminal N-acetyl hexosamines. Mutations in this gene result in GM2-gangliosidosis type AB or the AB variant of Tay-Sachs disease. Alternative splicing results in multiple transcript variants.

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Bezeichner auf Proteinebene für GM2A

GM2 ganglioside activator protein , ganglioside GM2 activator , GM2 ganglioside activator , GM2 activator protein , cerebroside sulfate activator protein , shingolipid activator protein 3 , sphingolipid activator protein 3

GENE ID SPEZIES
282838 Rattus norvegicus
471705 Pan troglodytes
479324 Canis lupus familiaris
504524 Bos taurus
548463 Xenopus (Silurana) tropicalis
550529 Danio rerio
779153 Xenopus laevis
100174922 Felis catus
2760 Homo sapiens
14667 Mus musculus
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