anti-G Protein-Coupled Receptor 124 (GPR124) Antikörper

Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Zusätzlich bieten wir Ihnen GPR124 Kits (1) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
GPR124 25960 Q96PE1
GPR124 78560 Q91ZV8
GPR124 100363275  
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Top anti-GPR124 Antikörper auf antikoerper-online.de

Showing 10 out of 73 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human lung, adenocarcinoma. Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2171] - Analysis of anti-GPR124 / TEM5 antibody with human colon carcinoma, neoplastic cells. 0.05 mL Anmelden zum Anzeigen 7 bis 9 Tage
$514.63
Details
Human Kaninchen Unkonjugiert IF, ELISA Immunofluorescence analysis of HeLa cells, using GPR124 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$474.10
Details
Human Kaninchen Unkonjugiert EIA, IHC (p), WB   0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage
$474.10
Details
Human Kaninchen Unkonjugiert ELISA, WB Western blot analysis GPR124 using LOVO whole cell lysates 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$523.71
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB   100 μg Anmelden zum Anzeigen 15 bis 19 Tage
$523.71
Details
Fledermaus Kaninchen Unkonjugiert IHC (p) Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2167] - Analysis of anti-GPR124 / TEM5 antibody with colon carcinoma, neoplastic cells at 4 ug/ ml. Immunohistochemistry-Paraffin: TEM5/GPR124 Antibody [NLS2167] - Analysis of anti-GPR124 / TEM5 antibody with human lung, adenocarcinoma. 0.05 mL Anmelden zum Anzeigen 10 bis 13 Tage
$514.63
Details
Human Maus Unkonjugiert CyTOF, FACS Detection of TEM5/GPR124 in HEK293 Human Cell Line Transfected with Human TEM5/GPR124 and eGFP by Flow Cytometry. HEK293 human embryonic kidney cell line transfected with human TEM5/GPR124 and eGFP was stained with either (A) Mouse Anti-Human TEM5/GPR124 Monoclonal Antibody. 100 μg Anmelden zum Anzeigen 8 bis 9 Tage
$323.15
Details
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse embryo tissue labeled with Anti GPR124 Polyclonal Antibody, Unconjugated (ABIN763151) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details

Am meisten referenzierte anti-GPR124 Antikörper

  1. Human Polyclonal GPR124 Primary Antibody für IHC, ELISA - ABIN1003261 : Carson-Walter, Watkins, Nanda, Vogelstein, Kinzler, St Croix: Cell surface tumor endothelial markers are conserved in mice and humans. in Cancer research 2001 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal GPR124 Primary Antibody für IHC, ELISA - ABIN1003260 : Vallon, Essler: Proteolytically processed soluble tumor endothelial marker (TEM) 5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v)beta3 to glycosaminoglycans. in The Journal of biological chemistry 2006 (PubMed)
    Show all 4 Pubmed References

Weitere Antikörper gegen GPR124 Interaktionspartner

Human G Protein-Coupled Receptor 124 (GPR124) Interaktionspartner

  1. Data suggest that GPR124 promotes cell adhesion via interaction with Elmo1 (zeige ELMO1 Antikörper)-Dock180 (zeige DOCK1 Antikörper) and intersectin 1 (zeige ITSN1 Antikörper)/2; this constitutes a previously unrecognized heteromeric complex that is putatively involved in GPR124-dependent adhesive/angiogenic responses in vascular endothelial cells. (GPR124 = G-protein coupled receptor 124; Elmo1 (zeige ELMO1 Antikörper) = ELMO domain-containing protein 1 (zeige ELMOD1 Antikörper); Dock180 (zeige DOCK1 Antikörper) = dedicator of cytokinesis protein 1 (zeige DOCK1 Antikörper) 180 kDa)

  2. Observed an inverse correlation between the expression of miR (zeige MLXIP Antikörper)-138-5p and GPR124 in lung adenocarcinoma specimens. Knockdown of GPR124 mimicked the effects of miR (zeige MLXIP Antikörper)-138-5p on the sensitivity to gefitinib.

  3. Thrombin (zeige F2 Antikörper)-induced shedding of tumour endothelial marker 5 and exposure of its RGD motif are regulated by cell-surface protein (zeige CD28 Antikörper) disulfide-isomerase (zeige P4HB Antikörper).

  4. TEM5 expression during capillary morphogenesis is induced by the small GTPase (zeige RACGAP1 Antikörper) Rac (zeige AKT1 Antikörper) and mediates contact inhibition of proliferation in endothelial cells.

  5. Proteolytically processed soluble tumor endothelial marker TEM5 mediates endothelial cell survival during angiogenesis by linking integrin alpha(v (zeige ITGAV Antikörper))beta3 to glycosaminoglycans

Mouse (Murine) G Protein-Coupled Receptor 124 (GPR124) Interaktionspartner

  1. experiments indicate that Reck (zeige RECK Antikörper) and Gpr124 are part of the cell surface protein (zeige CD28 Antikörper) complex that transduces Wnt7a (zeige WNT7A Antikörper)- and Wnt7b (zeige WNT7B Antikörper)-specific signals in mammalian CNS Epithelial Cells to promote angiogenesis and regulate the BBB (zeige ALMS1 Antikörper).

  2. Gpr124 is an endothelial GPCR (zeige GPBAR1 Antikörper) specifically required for endothelial Wnt (zeige WNT2 Antikörper) signaling and BBB (zeige ALMS1 Antikörper) integrity under pathological conditions in adult mice.

  3. Vital role for GPR124 is potentiation of WNT7 (zeige WNT7B Antikörper)-induced canonical beta-catenin (zeige CTNNB1 Antikörper) signaling with important implications for understanding and manipulating CNS-specific angiogenesis.

  4. Gpr124 functions as coactivator of Wnt7a (zeige WNT7A Antikörper)- and Wnt7b (zeige WNT7B Antikörper)-stimulated canonical Wnt (zeige WNT2 Antikörper) signaling via Frizzled receptor and Lrp (zeige LRP1 Antikörper) coreceptor and that Gpr124-stimulated signaling functions in concert with Norrin (zeige NDP Antikörper)/Frizzled4 (zeige FZD4 Antikörper) signaling to control CNS vascular development

  5. GPR124, an orphan G protein-coupled receptor (zeige GPRC5C Antikörper), is required for CNS-specific vascularization and establishment of the blood-brain barrier.

  6. TGF-beta (zeige TGFB1 Antikörper) stimulates Gpr124 expression which is required for angiogenic sprouting into neural tissues.

  7. study shows that complete null or endothelial-specific GPR124 deletion resulted in embryonic lethality from CNS-specific angiogenesis arrest in forebrain and neural tube; results demonstrate CNS-specific angiogenesis regulation by an endothelial receptor

Xenopus laevis G Protein-Coupled Receptor 124 (GPR124) Interaktionspartner

Zebrafish G Protein-Coupled Receptor 124 (GPR124) Interaktionspartner

  1. The GPI (zeige ITGA2 Antikörper)-anchored MMP inhibitor Reck (zeige RECK Antikörper) and the adhesion GPCR Gpr124 are integral components of the Wnt7a (zeige WNT7A Antikörper)/Wnt7b (zeige WNT7B Antikörper)-specific signaling complex required for brain angiogenesis and dorsal root ganglia neurogenesis.

GPR124 Antigen-Profil

Protein Überblick

Endothelial receptor that acts as an essential regulator of CNS angiogenesis. Required for normal endothelial cell sprouting and migration in the forebrain and neural tube.

Genbezeichner und Symbole assoziert mit GPR124

  • adhesion G protein-coupled receptor A2 (ADGRA2) Antikörper
  • adhesion G protein-coupled receptor A2 (Adgra2) Antikörper
  • adhesion G protein-coupled receptor A2 L homeolog (adgra2.L) Antikörper
  • adhesion G protein-coupled receptor A2 (adgra2) Antikörper
  • G-protein coupled receptor 124 (LOC616111) Antikörper
  • 8430414O08Rik Antikörper
  • 9530074E10Rik Antikörper
  • GPR124 Antikörper
  • MGC69043 Antikörper
  • mKIAA1531 Antikörper
  • si:dkey-208c22.2 Antikörper
  • Tem5 Antikörper

Bezeichner auf Proteinebene für GPR124

G-protein coupled receptor 124 , tumor endothelial marker 5 , G protein-coupled receptor 124 , probable G-protein coupled receptor 124-like

GENE ID SPEZIES
25960 Homo sapiens
78560 Mus musculus
399052 Xenopus laevis
426771 Gallus gallus
472739 Pan troglodytes
482853 Canis lupus familiaris
560700 Danio rerio
616111 Bos taurus
698629 Macaca mulatta
100059646 Equus caballus
100363275 Rattus norvegicus
100472498 Ailuropoda melanoleuca
100524344 Sus scrofa
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