anti-Friend Leukemia Virus Integration 1 (FLI1) Antikörper

FLI1 encodes a protein with a gelsolin-like actin binding domain and an N-terminal leucine-rich repeat-protein protein interaction domain. Zusätzlich bieten wir Ihnen Friend Leukemia Virus Integration 1 Proteine (8) und Friend Leukemia Virus Integration 1 Kits (7) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FLI1 2313 Q01543
FLI1 315532  
FLI1 14247 P26323
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Showing 10 out of 184 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-FLI1 Antibody Titration:  1.25ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate FLI1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$229.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti-FLI1 antibody, Western blotting Lane 1: JURKAT Cell Lysate Lane 2: RAJI Cell Lysate Anti-FLI1 antibody, IHC(P) IHC(P): Rat Spleen Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB WB Suggested Anti-FLI1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:312500  Positive Control:  Jurkat cell lysate FLI1 is strongly supported by BioGPS gene expression data to be expressed in Human Jurkat cells Rabbit Anti-FLI1 Antibody       Paraffin Embedded Tissue:  Human cardiac cell   Cellular Data:  Epithelial cells of renal tubule  Antibody Concentration:   4.0-8.0 ug/ml  Magnification:   400X 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Huhn Kaninchen Unkonjugiert IHC, WB Immunohistochemical analysis of FLI1 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with haematoxylin and mounted with DPX. Western blot analysis of FLI1 expression in HeLa (A), Jurkat (B), mouse liver (C), rat liver (D) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Kaninchen Unkonjugiert IHC, ELISA, WB Western blot analysis of extracts from NIH-3T3 cells, using FLI1 Antibody. The lane on the right is treated with the synthesized peptide. Immunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue, using FLI1 Antibody. The picture on the right is treated with the synthesized peptide. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
$302.50
Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of FLI1 antibody (N-term) (ABIN390410) in 293 cell line lysates (35 µg/lane). FLI1 (arrow) was detected using the purified polyclonal antibody. FLI-1 Antibody (N-term) (ABIN390410) IHC analysis in formalin fixed and paraffin embedded human tonsil tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IF, WB Western blot analysis of FLI1 antibody (Center) (ABIN390409) in mouse lung tissue lysates(35 µg/lane). FLI1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FLI1 antibody (Center) in mouse lung tissue lysates(35 µg/lane). FLI1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FLI1 antibody (N-term) in 293 cell line lysates (35 µg/lane). FLI1 (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Maus Unkonjugiert IF, WB Immunofluorescence of monoclonal antibody to FLI1 on HeLa cell (antibody concentration 10 µg/mL). FLI1 monoclonal antibody (M07), clone 1H4 Western Blot analysis of FLI1 expression in Jurkat. 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details

Am meisten referenzierte anti-Friend Leukemia Virus Integration 1 Antikörper

  1. Cow (Bovine) Polyclonal FLI1 Primary Antibody für WB - ABIN2780392 : van den Akker, van Dijk, Schmidt, Felida, Beug, Loewenberg, von Lindern: The Btk inhibitor LFM-A13 is a potent inhibitor of Jak2 kinase activity. in Biological chemistry 2004 (PubMed)
    Show all 3 Pubmed References

Weitere Antikörper gegen Friend Leukemia Virus Integration 1 Interaktionspartner

Human Friend Leukemia Virus Integration 1 (FLI1) Interaktionspartner

  1. These results indicate that Fli1 deficiency promotes migration, proliferation and cell survival, while abating tube formation of endothelial cells, suggesting that Fli1 deficiency is potentially attributable to the development of both proliferative obliterative vasculopathy (occlusion of arterioles and small arteries) and destructive vasculopathy (loss of small vessels) characteristic of SSc (zeige CYP11A1 Antikörper) vasculopathy.

  2. Fli1 functioned as an oncogene (zeige RAB1A Antikörper) in HCC (zeige FAM126A Antikörper) carcinogenesis and it exerted its promoting metastatic effect primarily by modulating the matrix metalloproteinase (MMP)2 (zeige MMP2 Antikörper) signaling pathway.

  3. Decreased serum LIF levels may be associated with vasculopathy in systemic sclerosis (SSc) and that Fli1 deficiency may contribute to the inhibition of LIF-dependent biological effects on SSc endothelial cells by suppressing the expression of LIF, LIF receptor, and gp130.

  4. Studies demonstrate that the translocation-derived fusion protein EF (EWS (zeige EWSR1 Antikörper)-FLI1) misregulates numerous genes involved in metabolism suggesting that EF is a master regulator of metabolic reprogramming in Ewing sarcoma, diverting metabolites toward biosynthesis.

  5. The gene that was most reproducibly up-regulated by EWS (zeige EWSR1 Antikörper)/FLI (zeige FLII Antikörper) was NR0B1 (zeige NR0B1 Antikörper).

  6. The mouse (Fli1) and human Fli1 genes are similarly regulated by Ets (zeige ETS1 Antikörper) factors in T cells.

  7. In contrast, expression of Spi1 (zeige SPI1 Antikörper)/PU.1 in a Fli1 producing erythroleukemia cell line in which fli1 is activated, resulted in increased proliferation through activation of growth promoting proteins MAPK (zeige MAPK1 Antikörper), AKT (zeige AKT1 Antikörper), cMYC (zeige MYC Antikörper) and JAK2 (zeige JAK2 Antikörper)

  8. CXCL6 expression is upregulated by Fli1 deficiency in fibroblasts and endothelial cells, potentially contributing to the development of fibrosis and vasculopathy in the skin, lung, and heart of systemic sclerosis.

  9. This is the first report presenting CD13 (zeige ANPEP Antikörper) and FLI1 as important mediators of resistance to BRAF (zeige BRAF Antikörper) inhibition with potential as drug targets in BRAF (zeige BRAF Antikörper) inhibitors refractory melanoma.

  10. This study uncovers FLI1 as an important driving factor that promotes tumor growth in SCLC through the miR-17-92 pathway. FLI1 may serve as an attractive target for therapeutic intervention of SCLC.

Xenopus laevis Friend Leukemia Virus Integration 1 (FLI1) Interaktionspartner

Mouse (Murine) Friend Leukemia Virus Integration 1 (FLI1) Interaktionspartner

  1. the Fox transcription factor binding motif was frequently observed within EWS (zeige EWSR1 Antikörper)-FLI1 peaks and Foxq1 (zeige FOXQ1 Antikörper) was identified as the cooperative partner that interacts with the EWS (zeige EWSR1 Antikörper) portion of EWS (zeige EWSR1 Antikörper)-FLI1.

  2. Decreased serum LIF levels may be associated with vasculopathy in systemic sclerosis (SSc) and that Fli1 deficiency may contribute to the inhibition of LIF-dependent biological effects on SSc endothelial cells by suppressing the expression of LIF, LIF receptor, and gp130.

  3. Histones showed limited activation in regions of single TF binding, while enhancers that bind NF-E2 (zeige NFE2 Antikörper) and either RUNX1 (zeige RUNX1 Antikörper), FLI1 or both TFs gave the highest signals for TF occupancy and H3K4me2; these enhancers associated best with genes activated late in MK maturation.

  4. loss of ERG (zeige ERG Antikörper) and FLI1 might contribute to the pathogenesis of vascular lung complications through the induction of inflammation.

  5. These results provide the first evidences that Fli-1 positively regulates LPS (zeige TLR4 Antikörper)-induced IL-27 (zeige IL27 Antikörper) production in macrophages

  6. protective against nephritis MRL/lpr (zeige FAS Antikörper) mice

  7. Fli1 is epigenetically suppressed and is a potential predisposing factor in the pathogenesis of systemic sclerosis. (Review)

  8. The short nose, otitis media, and hearing impairment in Jacobsen syndrome are likely because of hemizygosity for ETS1 (zeige ETS1 Antikörper) and FLI1.

  9. Simultaneous downregulation of KLF5 (zeige KLF5 Antikörper) and Fli1 is a key feature underlying systemic sclerosis.

  10. bosentan...increased DNA binding of Fli1 and the suppression of type I collagen expression in systemic sclerosis fibroblasts

Zebrafish Friend Leukemia Virus Integration 1 (FLI1) Interaktionspartner

  1. mesodermal Wnt3a (zeige WNT3A Antikörper)-mediated signaling via the transcription factor Lef1 (zeige LEF1 Antikörper) positively regulates EC specification (defined by kdrl expression) at the expense of primitive erythrocyte specification (defined by gata1 (zeige GATA1 Antikörper) expression) in zebrafish embryos.

  2. Fli+ etsrp (zeige ETV2 Antikörper)+ hemato-vascular progenitor cells proliferate at the lateral plate mesoderm during vasculogenesis in zebrafish.

  3. These results showed that young thrombocytes have higher GATA1 (zeige GATA1 Antikörper) promoter activity, while mature thrombocytes have more fli1 gene promoter transcription.

  4. fli1, and etsrp (zeige ETV2 Antikörper), demonstrated that erg (zeige KCNH2 Antikörper) and fli1 act cooperatively and are required for angiogenesis possibly via direct regulation of an endothelial cell junction molecule, VE-cadherin (zeige CDH5 Antikörper)

  5. Interaction between EWSR1 (zeige EWSR1 Antikörper)/FLI1 and EWSR1 (zeige EWSR1 Antikörper) in Ewing sarcoma may induce mitotic defects leading to genomic instability and subsequent malignant transformation.

Friend Leukemia Virus Integration 1 (FLI1) Antigen-Profil

Protein Überblick

This gene encodes a transcription factor containing an ETS DNA-binding domain. The gene can undergo a t(11\;22)(q24\;q12) translocation with the Ewing sarcoma gene on chromosome 22, which results in a fusion gene that is present in the majority of Ewing sarcoma cases. An acute lymphoblastic leukemia-associated t(4\;11)(q21\;q23) translocation involving this gene has also been identified. Alternative splicing results in multiple transcript variants.

Genbezeichner und Symbole assoziert mit FLI1

  • Fli-1 proto-oncogene, ETS transcription factor (FLI1) Antikörper
  • Fli-1 proto-oncogene, ETS transcription factor (Fli1) Antikörper
  • Fli-1 proto-oncogene, ETS transcription factor S homeolog (fli1.S) Antikörper
  • Fli-1 proto-oncogene, ETS transcription factor (fli1) Antikörper
  • Friend leukemia integration 1 (Fli1) Antikörper
  • Fli-1 proto-oncogene, ETS transcription factor a (fli1a) Antikörper
  • Fli-1 proto-oncogene, ETS transcription factor L homeolog (fli1.L) Antikörper
  • cb855 Antikörper
  • EWSR2 Antikörper
  • fli Antikörper
  • Fli-1 Antikörper
  • fli1 Antikörper
  • MGC121593 Antikörper
  • SIC-1 Antikörper
  • Sic1 Antikörper
  • wu:fc45b11 Antikörper
  • Xfli Antikörper
  • Xfli-1 Antikörper
  • Xfli1 Antikörper
  • xlfli Antikörper

Bezeichner auf Proteinebene für FLI1

Ewing sarcoma breakpoint region 2 , Friend leukemia integration 1 transcription factor , Friend leukemia virus integration 1 , proto-oncogene Fli-1 , transcription factor ERGB , fli-1 proto-oncogene , friend leukemia integration 1 transcription factor-like , Friend leukemia integration 1 transcription factor-like , retroviral integration site protein Fli-1 , retroviral integration site protein Fli-1 homolog

GENE ID SPEZIES
2313 Homo sapiens
315532 Rattus norvegicus
419723 Gallus gallus
451659 Pan troglodytes
489286 Canis lupus familiaris
529124 Bos taurus
100020764 Monodelphis domestica
100036985 Xenopus laevis
100124738 Xenopus (Silurana) tropicalis
100338376 Oryctolagus cuniculus
100411928 Callithrix jacchus
100445127 Pongo abelii
100469052 Ailuropoda melanoleuca
100545965 Meleagris gallopavo
100607271 Nomascus leucogenys
14247 Mus musculus
30619 Danio rerio
399466 Xenopus laevis
100064591 Equus caballus
100716275 Cavia porcellus
101090716 Felis catus
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