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The protein encoded by FHL3 is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. Zusätzlich bieten wir Ihnen Four and A Half LIM Domains 3 Proteine (7) und viele weitere Produktgruppen zu diesem Protein an.
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the present study established a link between Ang (zeige ANG Antikörper) and FHL3 proteins and identifies a new pathway for regulating astrocytoma progression.
These findings suggest that functional interactions between FHL3 and MT-1X (zeige MT1X Antikörper) may provide some clues to the mechanisms of FHL3-regulated cell proliferation.
PCBP2 (zeige PCBP2 Antikörper) could bind to FHL3 mRNA 3'UTR (zeige UTS2R Antikörper)-A and inhibited the expression of FHL3 in T98G glioms cells
FHL3 enhances Tax1 (zeige CNTN2 Antikörper)-mediated activation of the Human T-cell leukemia virus type 1 long terminal repeat (LTR) without affecting basal activity and regulates NF-kappaB (zeige NFKB1 Antikörper) activation by Tax1 (zeige CNTN2 Antikörper) in a cell-specific manner.
findings suggest that the interaction between Ang (zeige ANG Antikörper) and FHL3 may provide some clues to the mechanisms of Ang (zeige ANG Antikörper)-regulated cell growth and apoptosis
FHL3 suppressed anchorage-dependent and -independent growth of human breast cancer cells.
FHL3 does not bind to HIF-1alpha (zeige HIF1A Antikörper) or p300 (zeige EP300 Antikörper), indicating that it regulates transactivation by a novel molecular mechanism.
the second zinc finger motif in LIM4 was responsible for the auto-activation of FHL3.
Data show that FHL3 (human four-and-a-half LIM-only protein 3 (zeige LMO3 Antikörper)) interacts with human phosphatase CDC25B (zeige CDC25B Antikörper) in the cell nucleus.
FHL2 (zeige FHL2 Antikörper) and FHL3, respectively, are colocalized with alpha(7)beta(1) integrin receptor at the periphery of Z-discs, suggesting a role in mechanical stabilization of muscle cells
Four and a half LIM domain protein (zeige PDLIM7 Antikörper) 3 (zeige HSPB3 Antikörper) could interact with MyoD (zeige MYOD1 Antikörper), cyclic AMP (zeige TMPRSS5 Antikörper)-responsive elements and phosphorylated cAMP response element binding protein in vivo
Actin was identified as a FHL3 binding partner; FHL3 is a significant regulator of actin cytoskeletal dynamics in skeletal myoblasts.
These studies demonstrate that Sox15 (zeige SOX15 Antikörper), Fhl3 and Foxk1 (zeige Foxk1 Antikörper) function to coordinately regulate the myogenic progenitor cell population and skeletal muscle regeneration.
The protein encoded by this gene is a member of a family of proteins containing a four-and-a-half LIM domain, which is a highly conserved double zinc finger motif. The encoded protein has been shown to interact with the cancer developmental regulators SMAD2, SMAD3, and SMAD4, the skeletal muscle myogenesis protein MyoD, and the high-affinity IgE beta chain regulator MZF-1. This protein may be involved in tumor suppression, repression of MyoD expression, and repression of IgE receptor expression. Two transcript variants encoding different isoforms have been found for this gene.
four and a half LIM domains 3
, four and a half LIM domains protein 3
, LIM-only protein FHL3
, skeletal muscle LIM-protein 2