anti-Four and A Half LIM Domains 1 (FHL1) Antikörper

FHL1 encodes a member of the four-and-a-half-LIM-only protein family. Zusätzlich bieten wir Ihnen Four and A Half LIM Domains 1 Kits (14) und Four and A Half LIM Domains 1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FHL1 2273 Q13642
FHL1 14199 P97447
FHL1 25177 Q9WUH4
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Top anti-Four and A Half LIM Domains 1 Antikörper auf antikoerper-online.de

Showing 10 out of 118 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IC, IF, WB 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB Human kidney WB Suggested Anti-FHL1 Antibody Titration:  0.1ug/ml  ELISA Titer:  1:312500  Positive Control:  Human Muscle 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$249.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Host: Mouse Target Name: FHL1 Sample Tissue: Mouse Testis Antibody Dilution: 1ug/ml Host: Rabbit Target Name: FHL1 Sample Type: Human Fetal Brain Antibody Dilution: 1.0ug/ml 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert IHC, ELISA, WB ABIN185289 staining (0.05µg/ml) of Human Muscle lysate (RIPA buffer, 35µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.62
Details
Human Ziege Unkonjugiert ELISA, WB ABIN185290 (0.01µg/ml) staining of Human Heart lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$429.62
Details
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p), WB Immunocytochemistry/Immunofluorescence: FHL1 Antibody [NBP1-88745] - Staining of human cell line U-251MG shows positivity in cytoplasm. Immunohistochemistry-Paraffin: FHL1 Antibody [NBP1-88745] - Staining of human skeletal muscle shows strong nuclear and cytoplasmic positivity in myocytes. 0.1 mL Anmelden zum Anzeigen 34 Days
$491.63
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: FHL1 Antibody [NBP2-16490] - Immunohistochemical analysis of paraffin-embedded U87 xenograft, using antibody at 1:500 dilution. Western Blot: FHL1 Antibody [NBP2-16490] - Sample (30 ug of whole cell lysate) A: Jurktat 12% SDS PAGE gel, diluted at 1:2000. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
$514.63
Details
Human Maus Unkonjugiert FACS, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Hund Maus Unkonjugiert FACS, IF, WB 100 μL Anmelden zum Anzeigen 7 bis 9 Tage
$507.83
Details
Human Maus Unkonjugiert ELISA, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (36.52 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
$461.00
Details

Am meisten referenzierte anti-Four and A Half LIM Domains 1 Antikörper

  1. Cow (Bovine) Polyclonal FHL1 Primary Antibody für IHC, WB - ABIN2775759 : McGrath, Mitchell, Coghill, Robinson, Brown: Skeletal muscle LIM protein 1 (SLIM1/FHL1) induces alpha 5 beta 1-integrin-dependent myocyte elongation. in American journal of physiology. Cell physiology 2003 (PubMed)
    Show all 12 Pubmed References

  2. Human Polyclonal FHL1 Primary Antibody für IHC (p), IHC - ABIN250288 : Brown, McGrath, Ooms, Gurung, Maimone, Mitchell et al.: Characterization of two isoforms of the skeletal muscle LIM protein 1, SLIM1. Localization of SLIM1 at focal adhesions and the isoform slimmer in the nucleus of myoblasts and cytoplasm of myotubes ... in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 Pubmed References

  3. Human Polyclonal FHL1 Primary Antibody für ELISA, WB - ABIN250290 : Zhang, Chen, Sharma, Moon, Sheftel, Dawood, Nghiem, Wu, Li, Gramolini, Sorensen, Penninger, Brumell, Liu: HACE1-dependent protein degradation provides cardiac protection in response to haemodynamic stress. in Nature communications 2014 (PubMed)
    Show all 2 Pubmed References

  4. Human Polyclonal FHL1 Primary Antibody für IHC, ELISA - ABIN185289 : Samson, Smyth, Janetzky, Wendler, Müller, Schüle, von der Mark, von der Mark, Wixler: The LIM-only proteins FHL2 and FHL3 interact with alpha- and beta-subunits of the muscle alpha7beta1 integrin receptor. in The Journal of biological chemistry 2004 (PubMed)
    Show all 4 Pubmed References

  5. Human Monoclonal FHL1 Primary Antibody für ELISA, WB - ABIN515655 : Sakashita, Mimori, Tanaka, Kamohara, Inoue, Sawada, Hirakawa, Mori: Clinical significance of loss of Fhl1 expression in human gastric cancer. in Annals of surgical oncology 2008 (PubMed)

  6. Human Monoclonal FHL1 Primary Antibody für ELISA, WB - ABIN560899 : Chen, Ferrington, Thompson: Carbonic anhydrase III and four-and-a-half LIM protein 1 are preferentially oxidized with muscle unloading. in Journal of applied physiology (Bethesda, Md. : 1985) 2008 (PubMed)

  7. Cow (Bovine) Polyclonal FHL1 Primary Antibody für IHC (p), ELISA - ABIN2473617 : Emmanuele, Kubota, Garcia-Diaz, Garone, Akman, Sánchez-Gutiérrez, Escudero, Kariya, Homma, Tanji, Quinzii, Hirano: Fhl1 W122S causes loss of protein function and late-onset mild myopathy. in Human molecular genetics 2015 (PubMed)

  8. Human Polyclonal FHL1 Primary Antibody für ICC, IF - ABIN4311629 : Ek, Andréasson, Hober, Kampf, Pontén, Uhlén, Merz, Borrebaeck: From gene expression analysis to tissue microarrays: a rational approach to identify therapeutic and diagnostic targets in lymphoid malignancies. in Molecular & cellular proteomics : MCP 2006 (PubMed)

Weitere Antikörper gegen Four and A Half LIM Domains 1 Interaktionspartner

Human Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. FHL1 increase inhibitory CDC25 (zeige RASGRF1 Antikörper) phosphorylation by forming a complex with CHK2 (zeige CHEK2 Antikörper) and CDC25 (zeige RASGRF1 Antikörper), and sequester CDC25 (zeige RASGRF1 Antikörper) in the cytoplasm by forming another complex with 14-3-3 (zeige YWHAQ Antikörper) and CDC25 (zeige RASGRF1 Antikörper), resulting in increased radioresistance in cancer cells.

  2. FHL1 promote paclitaxel resistance in hepatocellular carcinomas cells through regulating apoptosis induced by paclitaxel, suggesting that FHL1 may be a promising molecular target for Hepatocellular carcinoma therapy.

  3. Altogether, the specific localization of FHL1B and its modulation in disease-patient's myoblasts confirmed FHL1-related Emery-Dreifuss muscular dystrophy as a nuclear envelope disease.

  4. Low FHL1 expression is associated with head and neck squamous cell carcinoma.

  5. We have uncovered FHL1 as a novel potential regulator of calcium homeostasis in both fish and humans and have implicated it in isolated hypoparathyroidism.

  6. Mutations in FHL1 cause unclassifiable cardiomyopathy with coexisting Emery-Dreifuss muscular dystrophy.

  7. results provide evidence that FHL1A interacts with PLEKHG2 (zeige PLEKHG2 Antikörper) and regulates cell morphological change through the activity of PLEKHG2 (zeige PLEKHG2 Antikörper).

  8. a novel FHL1 splice site variant results in the absence of FHL1A and the abundance of FHL1C, which may contribute to the complex and severe phenotype of Uruguay syndrome.

  9. Knockdown of FHL1 with FHL1 small interfering RNA (siRNA) promoted tumor growth and Cyclin D and cyclin E (zeige CCNE1 Antikörper) were markedly elevated at both the protein and mRNA level.

  10. results indicate that anti-FHL1 autoantibodies in peripheral blood have promising potential as a biomarker to identify a subset of severe IIM.

Mouse (Murine) Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. KyoT2 downregulates airway remodeling and resistance in asthmatic mice through a Hes1 (zeige HES1 Antikörper)-dependent mechanism.

  2. Results found that osteogenesis increases with the overexpression of Fhl1 and decreases with reduced Fhl1 expression and suggest that Fhl1 mediates interacting estrogen and Wnt (zeige WNT2 Antikörper) signaling during osteogenesis.

  3. Findings indicate that loss of function is responsible for the myopathy in the Fhl1 W122S knock-in mice.

  4. The CSL (zeige SMPX Antikörper)-KyoT2 corepressor complex is a negative regulator of Notch (zeige NOTCH1 Antikörper) signaling.

  5. Data show that loss of FHL1 function leads to myopathy in vivo and suggest that loss of function of FHL1 may be one of the mechanisms underlying muscle dystrophy in patients with FHL1 mutations.

  6. Fhl1 transcriptional changes provide salutary effects on stressed myocytes in cardiomyopathy.

  7. Data suggest Fhl1 (four-and-a-half LIM domains protein 1) and FHL2 (four-and-a-half LIM domains protein 2 (zeige FHL2 Antikörper)) bind to and regulate activity of Prkd1 (protein kinase D (zeige PRKD1 Antikörper) 1) in cardiac/ventricular myocytes; knockdown of Fhl1 down-regulates Prkd1 (zeige PRKD1 Antikörper) activation.

  8. A novel mechanism involving four-and-a-half LIM domain protein (zeige PDLIM7 Antikörper)-1 and extracellular signal-regulated kinase-2 (zeige MAPK1 Antikörper) regulates titin (zeige TTN Antikörper) phosphorylation and mechanics.

  9. Wnt (zeige WNT2 Antikörper) signaling induces muscle cell differentiation, at least partly, through Fhl1 activation.

  10. FHL1 is a novel regulator of myosin-binding (zeige PPP1R12A Antikörper) protein C (zeige PROC Antikörper) activity that may have a role in sarcomere assembly

Pig (Porcine) Four and A Half LIM Domains 1 (FHL1) Interaktionspartner

  1. The LIM domain protein (zeige PDLIM7 Antikörper) FHL1C interacts with tight junction protein ZO-1 (zeige TJP1 Antikörper) contributing to the epithelial-mesenchymal transition of a breast adenocarcinoma cell line.

Four and A Half LIM Domains 1 (FHL1) Antigen-Profil

Protein Überblick

This gene encodes a member of the four-and-a-half-LIM-only protein family. Family members contain two highly conserved, tandemly arranged, zinc finger domains with four highly conserved cysteines binding a zinc atom in each zinc finger. Expression of these family members occurs in a cell- and tissue-specific mode and these proteins are involved in many cellular processes. Mutations in this gene have been found in patients with Emery-Dreifuss muscular dystrophy. Multiple alternately spliced transcript variants which encode different protein isoforms have been described.

Genbezeichner und Symbole assoziert mit FHL1

  • four and a half LIM domains 1 (fhl1) Antikörper
  • four and a half LIM domains 1 (FHL1) Antikörper
  • four and a half LIM domains 1a (fhl1a) Antikörper
  • Four and a half LIM domains protein 1 (fhl1) Antikörper
  • four and a half LIM domains 1 S homeolog (fhl1.S) Antikörper
  • four and a half LIM domains 1 (Fhl1) Antikörper
  • DKFZp468O1927 Antikörper
  • fhl Antikörper
  • FHL-1 Antikörper
  • Fhl1 Antikörper
  • FHL1A Antikörper
  • FHL1B Antikörper
  • fhla Antikörper
  • FLH1A Antikörper
  • KyoT Antikörper
  • MGC89165 Antikörper
  • SLIM Antikörper
  • SLIM-1 Antikörper
  • SLIM1 Antikörper
  • SLIMMER Antikörper
  • XMPMA Antikörper
  • zgc:92025 Antikörper

Bezeichner auf Proteinebene für FHL1

four and a half LIM domains 1 , four and a half LIM domains protein 1-like , four and a half LIM domains a , four and a half LIM domains protein 1 , Four and a half LIM domains protein 1 , four and a half lim domains protein 1 , LIM protein SLIMMER , four-and-a-half Lin11, Isl-1 and Mec-3 domains 1 , skeletal muscle LIM-protein 1 , FHL-1 , RAM14-1 , RBP-associated molecule 14-1 , SLIM , SLIM-1 , four and a half LIM domains 1 protein

GENE ID SPEZIES
448334 Xenopus (Silurana) tropicalis
710692 Macaca mulatta
100172515 Pongo abelii
100307044 Ovis aries
100357263 Oryctolagus cuniculus
100387250 Callithrix jacchus
100590327 Nomascus leucogenys
399646 Danio rerio
100196873 Salmo salar
100529032 Ictalurus punctatus
447182 Xenopus laevis
2273 Homo sapiens
14199 Mus musculus
25177 Rattus norvegicus
509056 Bos taurus
397667 Sus scrofa
492162 Canis lupus familiaris
Ausgewählte Anbieter für anti-Four and A Half LIM Domains 1 (FHL1) Antikörper
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