Formin-Like 2 (FMNL2) ELISA Kits

FMNL2 encodes a formin-related protein. Zusätzlich bieten wir Ihnen FMNL2 Antikörper (26) und FMNL2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
FMNL2 71409 A2APV2
FMNL2 114793 Q96PY5
Anti-Ratte FMNL2 FMNL2 311033  
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Top FMNL2 ELISA Kits auf

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human < 0.188 ng/mL 0.313 ng/mL - 20 ng/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage
Maus < 46.9 pg/mL 78 pg/mL - 5000 pg/mL   96 Tests Anmelden zum Anzeigen 11 bis 18 Tage

Weitere ELISA Kits für FMNL2 Interaktionspartner

Mouse (Murine) Formin-Like 2 (FMNL2) Interaktionspartner

  1. force generation in lamellipodia strongly depends on FMNL formin activity.

  2. FMNL1 and FMNL2 are required non-redundantly in the repair of damaged myofibrils.

  3. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  4. mDia1-FH2 has an effect on the conformation of actin filaments

Human Formin-Like 2 (FMNL2) Interaktionspartner

  1. Data indicate that the interaction of cortactin and formin-like 2 (FMNL2) could promote the invadopodia formation and matrix degradation.

  2. FMNL2 knockout cells were characterized by impaired filopodia formation similar to depletion of the Rho GTPase Cdc42.

  3. Data demonstrate that the FMNL2/COMMD10/p65 NF kappaB axis acts as a critical regulator in the maintenance of metastatic phenotypes in colorectal cancer.

  4. Our data proved that RMRP acted as an oncogene LncRNA to promote the expression of KRAS, FMNL2 and SOX9 by inhibiting miR-206 expression in lung cancer. These data suggested that RMRP might serve as a therapeutic target in lung adenocarcinoma

  5. FMNL2 is likely to be generally required in melanoma cells for invasion.

  6. miR-206 functioned as a tumor suppressor in the progression of colorectal cancer(CRC) by targeting FMNL2 and c-MET. Restoration of miR-206 expression may represent a promising therapeutic approach for targeting malignant CRC.

  7. Capping protein and FMNL2 functionally coregulate filament barbed-end assembly.

  8. The two interacting FMNL-Cdc42 heterodimers expose six membrane interaction motifs on a convex protein surface, the assembly of which may facilitate actin filament elongation at the leading edge of lamellipodia and filopodia.

  9. These data establish a role for FMNL2 in the regulation of beta1-integrin and provide a mechanistic understanding of the function of FMNL2 in cancer invasiveness.

  10. MiR-34a was down-regulated in colorectal cancer cells and inversely correlated with FMNL2 and E2F5 expressions. Our study suggests that miR-34a is an important tumor suppressor of CRC progression by targeting FMNL2 and E2F5.

  11. Rac1-induced actin assembly and subsequent AJ formation critically depends on FMNL2.

  12. miR-137, induced by its upstream transcription factor HMGA1, can suppress colorectal cancer cell invasion and metastasis by targeting FMNL2.

  13. Protein N-myristoylation plays critical roles in the cellular morphological changes induced by FMNL2 and FMNL3.

  14. FMNL2 is a novel elongation factor of actin filaments that constitutes the first Cdc42 effector promoting cell migration and actin polymerization at the tips of lamellipodia.

  15. formin-like 2 expression correlated positively with tumor differentiation (P = .046) and vascular invasion (P = .008). Patients whose tumors had lower formin-like 2 expression had shorter overall survival times

  16. Findings identify a novel EMT and tumor promoting function for FMNL2, which is involved in TGF-beta-induced EMT and colorectal carcinoma cell invasion via Smad3 effectors, or in collaboration with MAPK/MEK pathway.

  17. a novel regulatory and functional interaction between RhoC and FMNL2 for modulating cell shape and invasiveness and provide mechanistic insight into RhoC-specific signalling events.

  18. FMNL2 may play an important role in the metastasis of CRC and may be a useful marker for metastasis of CRC.

FMNL2 Antigen-Profil

Beschreibung des Gens

This gene encodes a formin-related protein. Formin-related proteins have been implicated in morphogenesis, cytokinesis, and cell polarity. Alternatively spliced transcript variants encoding different isoforms have been described but their full-length nature has yet to be determined.

Genbezeichner und Symbole assoziert mit Formin-Like 2 (FMNL2) ELISA Kits

  • formin-like 2 (Fmnl2) Antikörper
  • formin like 2 (FMNL2) Antikörper
  • formin-like protein 2 (LOC476151) Antikörper
  • formin-like 2a (fmnl2a) Antikörper
  • formin like 2 (Fmnl2) Antikörper
  • 5430425K04Rik Antikörper
  • FHOD2 Antikörper
  • fmnl2 Antikörper
  • Man Antikörper
  • si:ch211-279a7.1 Antikörper

Bezeichner auf Proteinebene für Formin-Like 2 (FMNL2) ELISA Kits

formin-like domain containing protein MAN , formin-like protein 2 , protein Man , formin homology 2 domain containing 2 , formin homology 2 domain-containing protein 2 , formin-like 2

71409 Mus musculus
114793 Homo sapiens
459663 Pan troglodytes
476151 Canis lupus familiaris
695391 Macaca mulatta
771739 Gallus gallus
100006456 Danio rerio
100543936 Meleagris gallopavo
311033 Rattus norvegicus
788312 Bos taurus
100723045 Cavia porcellus
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