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Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. Zusätzlich bieten wir Ihnen Flotillin 1 Antikörper (89) und Flotillin 1 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.
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FLOT1 is associated with aggressive characteristics of HCC (zeige FAM126A ELISA Kits)
This study presents the endocytic pathways of internalization for muscarinic type 3 receptor and flotillin-1/2 in salivary gland epithelial cells. knockdown of flot-1 or -2 by flotillin (zeige FLOT2 ELISA Kits)-specific siRNA prevented internalization and reduced the endocytic efficiency of muscarinic type 3 receptor.
Data show that overexpression of 4.1N (zeige EPB41L1 ELISA Kits) protein decreased expression of flotillin-1, decreased activation of beta-catenin (zeige CTNNB1 ELISA Kits)/Wnt (zeige WNT2 ELISA Kits) pathway in non-small-cell lung cancer (NSCLC) cells.
Upregulation of flotillin-1 promotes invasion and metastasis by activating TGF-beta (zeige TGFB1 ELISA Kits) signaling in nasopharyngeal carcinoma.
Flotillin-1 protein is upregulated in human endometrial cancer and localization shifts from epithelial to stromal with increasing tumor grade
Expression of flotillin-1 was associated with H-Ras (zeige HRAS ELISA Kits) in breast cancer, especially in TNBC (p < 0.001).
findings revealed the expression of flotillin 1 in gastric cancer samples is significantly higher than that of noncancer/normal tissues; findings suggest that flotillin 1 may be a novel biomarker for gastric cancer
miR (zeige MLXIP ELISA Kits)-506 expression was down-regulated in clear cell renal cell carcinoma (ccRCC) and correlated with advanced histologic grade, clinical stage, tumor stage, positive lymph node metastasis, and distant metastasis. FLOT1, a potential target gene of miR (zeige MLXIP ELISA Kits)-506, was inversely correlated with miR (zeige MLXIP ELISA Kits)-506 expression in ccRCC tissues.
polycystins are necessary for assembly of a novel flotillin (zeige FLOT2 ELISA Kits)-containing ciliary signaling complex and provide a molecular rationale for the common renal pathologies caused by OFD1 (zeige OFD1 ELISA Kits) and polycystin mutations.
Findings suggest that FLOT1 plays an important role in the proliferation and recurrence of transitional cell carcinoma.
an involvement of LRAP (zeige AMELX ELISA Kits) in lipid-raft-dependent signaling pathways are mediated by flotillin-1.
Downregulation of microRNA-182-5p contributes to renal cell carcinoma proliferation via activating the AKT (zeige AKT1 ELISA Kits)/FOXO3a (zeige FOXO3 ELISA Kits) signaling pathway with FLOT1 being a target.
The role of flotillin 1 and flotillin 2 (zeige FLOT2 ELISA Kits) in regulating amyloid beta production in a mouse model of cerebral amyloidosis, remains unlear.
elevated levels of Flotillin-1 in hippocampal tissue of mice trained in the Morris water maze confirmed the relevance of Flotillin-1 for memory-related processes in a mammalian system.
a novel signaling network containing FRS2 (zeige FRS2 ELISA Kits), CAP and flotillin-1
flotillins have a role in NPC1L1 (zeige NPC1L1 ELISA Kits)-mediated cholesterol uptake and NPC1L1 (zeige NPC1L1 ELISA Kits)-flotillins-postive cholesterol-enriched membrane microdomains are involved in the mechanism for efficient cholesterol absorption
Data suggest that the association between flotillin 1/2 microdomains and cortical cytoskeleton has important functions during neutrophil migration, in uropod formation, and in the regulation of myosin IIa.
LGI3 (zeige LGI3 ELISA Kits) interacts with Flo1 in the brain, and LGI3 (zeige LGI3 ELISA Kits)/Flo1 mediates APP (zeige APP ELISA Kits) trafficking and exosome formation in neuronal cells: reveals the details of the intracellular transport system and even the secretion pathway in the brain.
Flotillin-1 and caveolin-3 (zeige CAV3 ELISA Kits) may regulate muscle energy metabolism through the spatial and temporal segregation of key components of the insulin (zeige INS ELISA Kits) signaling, including GLUT4 (zeige SLC2A4 ELISA Kits) transport.
Flotillin-1 regulates ephrinB2 (zeige EFNB2 ELISA Kits) protein levels through ADAM10 (zeige ADAM10 ELISA Kits), and is required for appropriate neural tube morphogenesis in the Xenopus embryo.
At late tail bud stages, flotillin1A is expressed in branchial arch mesenchyme, the overlying branchial ectoderm and in dorsal somitic mesoderm, whereas flotillin1B expression is more restricted in the dorsal neural tube and head sensory structures.
These results provide the first in vivo evidence that Flotillins regulate E-cadherin (zeige CDH1 ELISA Kits)-mediated cell-cell junctions to allow epiboly progression.
Analysis of reggie mRNA and protein expression patterns during early zebrafish development revealed that re-1a mRNA is present at high levels in expression domains that overlap with the combined expression pattern of both re-2 (zeige GPR161 ELISA Kits) genes except at the somites.
Caveolae are small domains on the inner cell membrane involved in vesicular trafficking and signal transduction. FLOT1 encodes a caveolae-associated, integral membrane protein. The function of flotillin 1 has not been determined.
, integral membrane component of caveolae
, flotillin 1c
, flotillin 1a
, flotillin 1