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FLNC encodes one of three related filamin genes, specifically gamma filamin. Zusätzlich bieten wir Ihnen FLNC Kits (31) und FLNC Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 40 products:
Human Monoclonal FLNC Primary Antibody für IF, IP - ABIN968182
Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990
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Human Polyclonal FLNC Primary Antibody für ICC, IF - ABIN4312164
Valdés-Mas, Gutiérrez-Fernández, Gómez, Coto, Astudillo, Puente, Reguero, Álvarez, Morís, León, Martín, Puente, López-Otín: Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy. in Nature communications 2014
Show all 3 Pubmed References
Human Polyclonal FLNC Primary Antibody für ELISA, WB - ABIN560923
Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. in Genes to cells : devoted to molecular & cellular mechanisms 2013
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Cow (Bovine) Polyclonal FLNC Primary Antibody für WB - ABIN2789843
Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. in JACC. Basic to translational science 2016
HSPB7 (zeige HSPB7 Antikörper) is essential for maintaining muscle integrity, which is achieved through its interaction with FLNC
The data of this study presented here provide further support that FLNC, a muscle-specific protein (zeige TXLNB Antikörper), could be a potential novel player in FTD (zeige FTL Antikörper) pathogenesis.
Aciculin (zeige PGM5 Antikörper) interacts with filamin C and Xin (zeige XIRP1 Antikörper) and is essential for myofibril assembly.
KY, IGFN1 and FLNC are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.
filamin C may function in signal transduction or cellular migration of the myogenic progenitor cell population
These data provide the first evidence that FLNc has a crucial role in muscle development and maintenance of muscle structural integrity and suggest the presence of a TRIO (zeige TRIO Antikörper)-FLNc-dependent pathway in maintaining proper myotube structure.
MuRF3 (zeige TRIM54 Antikörper) has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (zeige FHL2 Antikörper) and gamma-filamin contributes to this cardioprotective function of MuRF3 (zeige TRIM54 Antikörper)
Cbl (zeige CBL Antikörper)-associated protein provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity
Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rac1/cdc42 (zeige CDC42 Antikörper) activites in esophageal squamous cell carcinoma.
Data show that the filamin C (FLNC) protein was significantly overexpressed with the development of hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)), which might play an important role in HCC (zeige FAM126A Antikörper) invasion and metastasis.
Missense variant in FLNC gene is associated with reading disability.
suggest that the combination of the OBSCN (zeige OBSCN Antikörper) p.Arg4444Trp variant and of the FLNC c.5161delG mutation, can cooperatively affect myofibril stability and increase the penetrance of muscular dystrophy in the French family
This study therefore identifies both BAG3 (zeige BAG3 Antikörper) reduction and autophagy promotion as potential therapies for FLNC(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.
Biallelic variants in FLNC can cause congenital dilated cardiomyopathy.
Truncating mutations in FLNC caused an overlapping phenotype of dilated and left-dominant arrhythmogenic cardiomyopathies complicated by frequent premature sudden death
a compelling evidence of the involvement of FLNC in the development of Hypertrophic Cardiomyopathy . Most of the FLNC variants were associated with mild forms ofHypertrophic Cardiomyopathy and a reduced penetrance
FLNC is a disease gene for autosomal-dominant Restrictive Cardiomyopathy and broadens the phenotype spectrum of filaminopathies.
The identification of Filamin C as a novel KCNE2 (zeige KCNE2 Antikörper) ligand not only enhances current understanding of ion channel function and regulation, but also provides valuable information about possible pathways likely to be involved in long-QT syndrome pathogenesis
This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.
filamin C, gamma (actin binding protein 280)
, gamma filamin
, filamin C, gamma
, ABP-280-like protein
, actin binding protein 280
, actin-binding protein 280
, actin-binding-like protein
, filamin, gamma
, ABP-L, gamma filamin
, filamin 2
, 260kDa actin-binding protein
, cgABP260 actin-binding domain