anti-Filamin C, gamma (FLNC) Antikörper

FLNC encodes one of three related filamin genes, specifically gamma filamin. Zusätzlich bieten wir Ihnen FLNC Kits (31) und FLNC Proteine (5) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FLNC 68794 Q8VHX6
FLNC 362332  
FLNC 2318 Q14315
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Top anti-FLNC Antikörper auf

Showing 10 out of 40 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-FLNC Antibody Titration: 1.0 ug/ml Positive Control: HepG2 Whole Cell 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Maus Unkonjugiert IF, IP, IHC, WB Western blot analysis of ABP-280 on a human endothelial cell lysate. Lane 1: 1:250, lane 2: 1:500, lane 3: 1:1000 dilution of the mouse anti-human ABP-280 antibody. 50 μg Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB Figure. DAB staining on IHC-P; Samples: Human Kidney Tissue. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC, IHC (p) Western Blot: FLNC Antibody [NBP1-89300] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunocytochemistry/Immunofluorescence: FLNC Antibody [NBP1-89300] - Staining of human cell line U-2 OS shows positivity in plasma membrane & cytoplasm. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p) Paraformaldehyde-fixed, paraffin embedded Mouse heart, Antigen retrieval by boiling in sodium citrate buffer (pH6.0) for 15min, Block endogenous peroxidase by 3% hydrogen peroxide for 20 minutes, Blocking buffer (normal goat serum) at 37°C for 30min, Antibody incubation with Filamin 2 Polyclonal Antibody, Unconjugated  at 1:400 overnight at 4°C, followed by a conjugated secondary and DAB staining. 100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Unkonjugiert ICC, IHC, WB Used in DAB staining on fromalin fixed paraffin-embedded Kidney tissue 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
Human Maus Unkonjugiert ELISA, WB FLNC polyclonal antibody (A01), Lot # FAK0070504QCS1 Western Blot analysis of FLNC expression in NIH/3T3 . Western Blot detection against Immunogen (37 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
Human Kaninchen Alexa Fluor 488 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen Cy3 IF (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage
Human Kaninchen HRP IHC (p)   100 μL Anmelden zum Anzeigen 14 bis 21 Tage

FLNC Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine) , ,

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Am meisten referenzierte anti-FLNC Antikörper

  1. Human Monoclonal FLNC Primary Antibody für IF, IP - ABIN968182 : Gorlin, Yamin, Egan, Stewart, Stossel, Kwiatkowski, Hartwig: Human endothelial actin-binding protein (ABP-280, nonmuscle filamin): a molecular leaf spring. in The Journal of cell biology 1990 (PubMed)
    Show all 6 Pubmed References

  2. Human Polyclonal FLNC Primary Antibody für ICC, IF - ABIN4312164 : Valdés-Mas, Gutiérrez-Fernández, Gómez, Coto, Astudillo, Puente, Reguero, Álvarez, Morís, León, Martín, Puente, López-Otín: Mutations in filamin C cause a new form of familial hypertrophic cardiomyopathy. in Nature communications 2014 (PubMed)
    Show all 3 Pubmed References

  3. Human Polyclonal FLNC Primary Antibody für ELISA, WB - ABIN560923 : Sakane, Alamir Mahmoud Abdallah, Nakano, Honda, Kitamura, Imoto, Matsushita, Sasaki: Junctional Rab13-binding protein (JRAB) regulates cell spreading via filamins. in Genes to cells : devoted to molecular & cellular mechanisms 2013 (PubMed)
    Show all 2 Pubmed References

  4. Cow (Bovine) Polyclonal FLNC Primary Antibody für WB - ABIN2789843 : Begay, Tharp, Martin, Graw, Sinagra, Miani, Sweet, Slavov, Stafford, Zeller, Alnefaie, Rowland, Brun, Jones, Gowan, Mestroni, Garrity, Taylor: FLNC Gene Splice Mutations Cause Dilated Cardiomyopathy. in JACC. Basic to translational science 2016 (PubMed)

Weitere Antikörper gegen FLNC Interaktionspartner

Mouse (Murine) Filamin C, gamma (FLNC) Interaktionspartner

  1. HSPB7 (zeige HSPB7 Antikörper) is essential for maintaining muscle integrity, which is achieved through its interaction with FLNC

  2. The data of this study presented here provide further support that FLNC, a muscle-specific protein (zeige TXLNB Antikörper), could be a potential novel player in FTD (zeige FTL Antikörper) pathogenesis.

  3. Aciculin (zeige PGM5 Antikörper) interacts with filamin C and Xin (zeige XIRP1 Antikörper) and is essential for myofibril assembly.

  4. KY, IGFN1 and FLNC are part of a Z-band associated protein complex likely to provide structural support to the skeletal muscle sarcomere.

  5. filamin C may function in signal transduction or cellular migration of the myogenic progenitor cell population

  6. These data provide the first evidence that FLNc has a crucial role in muscle development and maintenance of muscle structural integrity and suggest the presence of a TRIO (zeige TRIO Antikörper)-FLNc-dependent pathway in maintaining proper myotube structure.

  7. MuRF3 (zeige TRIM54 Antikörper) has an essential role in maintaining cardiac integrity and function after acute myocardial infarction and turnover of FHL2 (zeige FHL2 Antikörper) and gamma-filamin contributes to this cardioprotective function of MuRF3 (zeige TRIM54 Antikörper)

  8. Cbl (zeige CBL Antikörper)-associated protein provides another link between the myofibril cytoskeleton and the plasma membrane of muscle cells, and it may play a dynamic role in the regulation and maintenance of muscle structural integrity

Human Filamin C, gamma (FLNC) Interaktionspartner

  1. Filamin C promotes lymphatic invasion and lymphatic metastasis and increases cell motility by regulating Rac1/cdc42 (zeige CDC42 Antikörper) activites in esophageal squamous cell carcinoma.

  2. Data show that the filamin C (FLNC) protein was significantly overexpressed with the development of hepatocellular carcinoma (HCC (zeige FAM126A Antikörper)), which might play an important role in HCC (zeige FAM126A Antikörper) invasion and metastasis.

  3. Missense variant in FLNC gene is associated with reading disability.

  4. suggest that the combination of the OBSCN (zeige OBSCN Antikörper) p.Arg4444Trp variant and of the FLNC c.5161delG mutation, can cooperatively affect myofibril stability and increase the penetrance of muscular dystrophy in the French family

  5. This study therefore identifies both BAG3 (zeige BAG3 Antikörper) reduction and autophagy promotion as potential therapies for FLNC(W2710X) myofibrillar myopathy, and identifies protein insufficiency due to sequestration, compounded by impaired autophagy, as the cause.

  6. Biallelic variants in FLNC can cause congenital dilated cardiomyopathy.

  7. Truncating mutations in FLNC caused an overlapping phenotype of dilated and left-dominant arrhythmogenic cardiomyopathies complicated by frequent premature sudden death

  8. a compelling evidence of the involvement of FLNC in the development of Hypertrophic Cardiomyopathy . Most of the FLNC variants were associated with mild forms ofHypertrophic Cardiomyopathy and a reduced penetrance

  9. FLNC is a disease gene for autosomal-dominant Restrictive Cardiomyopathy and broadens the phenotype spectrum of filaminopathies.

  10. The identification of Filamin C as a novel KCNE2 (zeige KCNE2 Antikörper) ligand not only enhances current understanding of ion channel function and regulation, but also provides valuable information about possible pathways likely to be involved in long-QT syndrome pathogenesis

FLNC Antigen-Profil

Protein Überblick

This gene encodes one of three related filamin genes, specifically gamma filamin. These filamin proteins crosslink actin filaments into orthogonal networks in cortical cytoplasm and participate in the anchoring of membrane proteins for the actin cytoskeleton. Three functional domains exist in filamin: an N-terminal filamentous actin-binding domain, a C-terminal self-association domain, and a membrane glycoprotein-binding domain. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit FLNC

  • filamin C (FLNC) Antikörper
  • filamin C L homeolog (flnc.L) Antikörper
  • filamin C (flnc) Antikörper
  • filamin C, gamma (Flnc) Antikörper
  • filamin C (Flnc) Antikörper
  • 1110055E19Rik Antikörper
  • ABP-280 Antikörper
  • ABP280A Antikörper
  • ABPA Antikörper
  • ABPL Antikörper
  • FLN2 Antikörper
  • MFM5 Antikörper
  • MPD4 Antikörper

Bezeichner auf Proteinebene für FLNC

filamin C, gamma (actin binding protein 280) , gamma filamin , filamin C, gamma , filamin-C-like , ABP-280-like protein , ABP-L , FLN-C , actin binding protein 280 , actin-binding protein 280 , actin-binding-like protein , filamin, gamma , filamin-2 , filamin-C , gamma-filamin , ABP-L, gamma filamin , filamin 2 , 260kDa actin-binding protein , cgABP260 actin-binding domain

463711 Pan troglodytes
734178 Xenopus laevis
100329116 Xenopus (Silurana) tropicalis
100475857 Ailuropoda melanoleuca
68794 Mus musculus
362332 Rattus norvegicus
2318 Homo sapiens
100730013 Cavia porcellus
100518997 Sus scrofa
482266 Canis lupus familiaris
528415 Bos taurus
395260 Gallus gallus
101104655 Ovis aries
Ausgewählte Anbieter für anti-FLNC (FLNC) Antikörper
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