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FCRL2 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. Zusätzlich bieten wir Ihnen FCRL2 Antikörper (22) und FCRL2 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.
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decreased FCRL4 expression and association of FCRL2 expression with inflammatory markers and disease activity suggested the contribution of these molecules to rheumatoid arthritis inflammatory processes.
FCRL2 overexpression in B cells from Hashimoto and Graves disease patients compared to normal subjects.
a negative immunomodulatory function for FCRL2 in the regulation of memory B cells.
B-CLL patients with high FCRL2 expression had a significantly longer treatment-free survival & overall survival than those with low FCRL2.
FCRL2 has robust predictive value for determining IGHV gene mutation status and clinical progression and thus may further improve prognostic definition in chronic lymphocytic leukemia.
Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.
Down-regulation of FCRL2 is associated with acute lymphoblastic leukemia.
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein has four extracellular C2-type immunoglobulin domains, a transmembrane domain and a cytoplasmic domain that contains one immunoreceptor-tyrosine activation motif and two immunoreceptor-tyrosine inhibitory motifs. This protein may be a prognostic marker for chronic lymphocytic leukemia. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.
Fc receptor-like protein 2
, IFGP family protein 4
, SH2 domain containing phosphatase anchor protein 1
, SH2 domain-containing phosphatase anchor protein 1
, fc receptor homolog 2
, fcR-like protein 2
, immune receptor translocation-associated protein 4
, immunoglobulin receptor translocation-associated protein 4
, immunoglobulin superfamily Fc receptor, gp42
, Fc receptor-like 2
, type I TM-receptor XFL1.1b
, Fc receptor-like protein 2-like