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FCRL1 encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. Zusätzlich bieten wir Ihnen FCRL1 Antikörper (47) und FCRL1 Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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FCRL1 gene expression down-regulates in both Hashimoto and Graves disease patients compared to normal subjects.
Data show the Differences in high resolution melting analysis in promoters of tumor markers neuronal membrane glycoprotein M6-B (zeige GPM6B ELISA Kits), melanoma antigen family A12 and immunoglobulin superfamily Fc receptor (zeige FCGRT ELISA Kits) indicated invasiveness of hepatocellular carcinoma.
Expression level of FCRL1 gene in peripheral blood B-lymphocytes is significantly higher in patients with autoimmune diseases.
FcRH1 thus has the potential to serve as an activating coreceptor on B cells.
Fc receptor-like 1-5 molecules are similarly expressed in progressive and indolent clinical subtypes of B-cell chronic lymphocytic leukemia.
Down-regulation of FCRL1 is associated with acute lymphoblastic leukemia.
This gene encodes a member of the immunoglobulin receptor superfamily and is one of several Fc receptor-like glycoproteins clustered on the long arm of chromosome 1. The encoded protein contains three extracellular C2-like immunoglobulin domains, a transmembrane domain and a cytoplasmic domain with two immunoreceptor-tyrosine activation motifs. This protein may play a role in the regulation of cancer cell growth. Alternative splicing results in multiple transcript variants.
Fc receptor-like protein 1
, IFGP family protein 1
, fc receptor homolog 1
, fcR-like protein 1
, immune receptor translocation-associated protein 5
, immunoglobulin superfamily Fc receptor, gp42
, BXMAS1-like protein 1
, BXMAS1-like protein 1b
, Fc receptor-like 1
, Fc receptor-like protein 1-like
, fc receptor 1-like protein