anti-Fat Mass and Obesity-Associated (FTO) Antikörper

FTO is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of FTO is not known. Zusätzlich bieten wir Ihnen FTO Proteine (10) und FTO Kits (9) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FTO 79068 Q9C0B1
FTO 26383 Q8BGW1
FTO 291905 Q2A121
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Top anti-FTO Antikörper auf antikoerper-online.de

Showing 10 out of 149 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert WB <b>WB Suggested Anti-FTO Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>PANC1 cell lysate WB Suggested Anti-FTO <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500 <br /> Positive Control: PANC1 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-Fto Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:1562500<br><b>Positive Control: </b>Mouse Brain WB Suggested Anti-Fto <br /> Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500 <br /> Positive Control: Mouse Brain 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB Western blot analysis of FTO expression in HepG2 (A), Caco2 (B), SHSY5Y (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
Details
Human Ziege Unkonjugiert ELISA, WB ABIN308414 (0.03µg/ml) staining of Human Pancreas lysate (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 100 μg Anmelden zum Anzeigen 6 bis 7 Tage
$358.02
Details
Human Kaninchen Unkonjugiert FACS, IHC, WB 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$245.00
Details
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of FTO Antibody (N-term) in NCI-H460 cell line lysates (35 µg/lane). FTO (arrow) was detected using the purified Pab. 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
$390.50
Details
Human Kaninchen Unkonjugiert WB Detection of FTO in human brain lysate using ABIN258809. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$444.19
Details
Human Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Rind (Kuh) Kaninchen Unkonjugiert IHC (p), WB Human Small Intestine: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$727.83
Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB Western blot analysis of FTO Antibody (N-term) (ABIN390964) in NCI-H460 cell line lysates (35 µg/lane). FTO (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human brain tissue reacted with FTO Antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
Details

FTO Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Am meisten referenzierte anti-FTO Antikörper

  1. Human Polyclonal FTO Primary Antibody für ELISA, WB - ABIN316349 : Gerken, Girard, Tung, Webby, Saudek, Hewitson, Yeo, McDonough, Cunliffe, McNeill, Galvanovskis, Rorsman, Robins, Prieur, Coll, Ma, Jovanovic, Farooqi, Sedgwick, Barroso, Lindahl, Ponting, Ashcroft et al.: The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase. ... in Science (New York, N.Y.) 2007 (PubMed)

  2. Human Polyclonal FTO Primary Antibody für WB - ABIN258809 : Walters, Mercaldo, Gillon, Yip, Neve, Boyce, Frankland, Josselyn: The Role of The RNA Demethylase FTO (Fat Mass and Obesity-Associated) and mRNA Methylation in Hippocampal Memory Formation. in Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2017 (PubMed)

Weitere Antikörper gegen FTO Interaktionspartner

Human Fat Mass and Obesity-Associated (FTO) Interaktionspartner

  1. Variations within FTO may be predictors of fatty liver disease in HIV-infected patients independently of metabolic factors.

  2. N(6)-Methyladenosine itself serves as a 'conformational marker', which induces different conformational outcomes in RNAs depending on sequence context. This critically impacts its interactions with several m6A (zeige GPM6A Antikörper)-recognising proteins, including FTO and ALKBH5 (zeige ALKBH5 Antikörper).

  3. Studied weight loss in obese patients with Perilipin 4 (PLIN4 (zeige PLIN4 Antikörper)), Fat mass and obesity-associated (FTO), and beta- adrenergic receptor 3 (ADRB3 (zeige ADRB3 Antikörper)) polymorphisms treated with Garcinia cambogia/Glucomannan. Results suggest weight loss was attenuated in carriers of PLIN4 (zeige PLIN4 Antikörper), FTO, ADRB3 (zeige ADRB3 Antikörper) polymorphisms.

  4. Fat mass and obesity associated (FTO) was the first gene found to be associated with obesity in three independent genome-wide association studies.

  5. It has been shown, that presence of one mutant allele of rs9939609 (gene FTO) and rs4994 (gene ADRB3 (zeige ADRB3 Antikörper)) leads to statistically significant association with obesity.

  6. Food advertisement exposure was associated with greater caloric consumption of a recently advertised food, and this effect was modified by an FTO genotype. Future research is needed to understand the neurological mechanism underlying these associations.

  7. FTO rs9939609 polymorphism is observed to be associated with obesity.

  8. FTO rs9939609 polymorphism in recurrent VTE may differ according to gender.

  9. the first intron of the FTO gene is associated with obesity in humans in a mechanism potentially involving the risk allele (rs1421085)

  10. The age of diabetes was not affect by the tested FTO polymorphisms (rs9939609 , rs1421085, and rs9930506).

Mouse (Murine) Fat Mass and Obesity-Associated (FTO) Interaktionspartner

  1. FTO is critically involved in insulin (zeige INS Antikörper) defects-related Alzheimer's disease.

  2. This is the first study revealing the presence of a parallel increase in expressions of FTO and HNRNPK (zeige HNRNPK Antikörper) proteins. This increase may codictate the metabolic changes occurring in the cell and may attribute a significance to HNRNPK (zeige HNRNPK Antikörper) in FTO-associated transformations.

  3. Contextual fear conditioning decreased FTO levels in neurons from the hippocampus.

  4. The involvement of mTOR (zeige FRAP1 Antikörper)-PGC-1alpha pathway in the connection between FTO and muscle differentiation is displayed.

  5. In vivo experiments revealed that Fto(-/-) and Fto(+/-) mice were more susceptible to thiopurine-induced myelosuppression than wild-type mice.

  6. propose that PKCbeta acts to suppress the degradation of FTO protein and reveals the associated role of PKCbeta and FTO in adipogenesis, suggesting a new pathway that affects the development of obesity and metabolic diseases

  7. the results of this study indicate that the effects of FTO-associated SNPs on energy homeostasis are due in part to the effects of these genetic variations on hypothalamic FTO, RPGRIP1L (zeige RPGRIP1L Antikörper), and possibly other genes.

  8. FTO may have a deleterious role in hepatic cells during lipotoxic conditions, and up-regulation of FTO may contribute to the increased liver damage in non-alcoholic steatohepatitis

  9. Fto deficiency affects the gene and miR130/miR378 expression involved in brown adipogenesis and browning of white adipose tissue in mice.

  10. Here we show that FTO expression is increased after ureteral obstruction and renal fibrosis.

Pig (Porcine) Fat Mass and Obesity-Associated (FTO) Interaktionspartner

  1. In this study, the authors characterise the nucleotide variability and haplotype diversity of the porcine fat mass and obesity-associated (FTO) gene in breeds having different predispositions to fat deposition traits.

  2. In pig, the FTO gene influences back fat depth in the commercial populations.

  3. This study will provide clues for obtaining a better understanding of the porcine FTO gene function.

  4. The results of the association analyses confirmed the effect of the FTO mutation on obesity-related traits in the Italian Duroc pigs (P < 0.01) and in the commercial pigs.

  5. The porcine fat mass and obesity associated (FTO) gene is associated with fat deposition in Italian Duroc pigs.

Cow (Bovine) Fat Mass and Obesity-Associated (FTO) Interaktionspartner

  1. 34 FTO polymorphisms revealed significant association of FTO variants with lean meat percentage in Simmental and Brown cattle breeds.

  2. association signals not only provided evidence for at least two causative mutations in the FTO locus with a functional effect on milk but also milk protein (zeige CSN2 Antikörper) yield

  3. Haplotype frequencies and linkage disequilibrium (LD) coefficients of FTO single nucleotide polymorphisms in three Chinese indigenous cattle breeds were analyzed.

FTO Antigen-Profil

Protein Überblick

This gene is a nuclear protein of the AlkB related non-haem iron and 2-oxoglutarate-dependent oxygenase superfamily but the exact physiological function of this gene is not known. Other non-heme iron enzymes function to reverse alkylated DNA and RNA damage by oxidative demethylation. Studies in mice and humans indicate a role in nervous and cardiovascular systems and a strong association with body mass index, obesity risk, and type 2 diabetes.

Genbezeichner und Symbole assoziert mit FTO

  • FTO, alpha-ketoglutarate dependent dioxygenase (FTO) Antikörper
  • fat mass and obesity associated (Fto) Antikörper
  • FTO, alpha-ketoglutarate dependent dioxygenase (Fto) Antikörper
  • fat mass and obesity associated L homeolog (fto.L) Antikörper
  • AW743446 Antikörper
  • mKIAA1752 Antikörper
  • RGD1305121 Antikörper

Bezeichner auf Proteinebene für FTO

alpha-ketoglutarate-dependent dioxygenase FTO , fat mass and obesity-associated protein , protein fto , protein fatso , fat mass and obesity associated protein , Protein fatso

GENE ID SPEZIES
79068 Homo sapiens
26383 Mus musculus
478125 Canis lupus familiaris
100127165 Sus scrofa
291905 Rattus norvegicus
100060565 Equus caballus
618622 Bos taurus
100125353 Ovis aries
447305 Xenopus laevis
100173222 Pongo abelii
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