Fas Apoptotic Inhibitory Molecule 2 Proteine (FAIM2)

may mediate development and maintenance of the nervous system [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen FAIM2 Antikörper (74) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
FAIM2 23017 Q9BWQ8
FAIM2 72393 Q8K097
Ratte FAIM2 FAIM2 246274 O88407
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 50 bis 55 Tage
Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 50 bis 55 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days

FAIM2 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Am meisten referenzierte FAIM2 Proteine

  1. Human FAIM2 Protein expressed in Wheat germ - ABIN1353388 : Müller, Maurer, Reimers, Vogt, Bucan: TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro. in International journal of oncology 2015 (PubMed)

Weitere Proteine zu Fas Apoptotic Inhibitory Molecule 2 (FAIM2) Interaktionspartnern

Human Fas Apoptotic Inhibitory Molecule 2 (FAIM2) Interaktionspartner

  1. results suggest that high level miR-3202 in T lymphocytes may protect epithelial cells through targeting FAIM2. MiR-3202 might be used as a notable biomarker of chronic obstructive pulmonary disease .

  2. that miR-193b is indispensible for the competitive endogenous RNA role of SNHG7 in FAIM2-supported tumourigenesis of lung cancer

  3. FAIM2 expression is significantly downregulated in human masticatory mucosa during wound healing

  4. our research showed that lncRNA-SNHG7 promotes the proliferation, migration and invasion, and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression, suggesting that lncRNA-SNHG7 as a key regulator of gene expression, may be a promising therapeutic strategy for the treatment of lung cancer

  5. The interaction of TRIM21 and LFG was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out.

  6. There are significant differences in the associations of the FAIM2 promoter methylation with sedentary behaviour and physical activity between obese and lean children.

  7. Methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children.

  8. Low KRT13 mRNA expression is associated with oral squamous cell carcinoma.

  9. These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2) homeostasis in a wide variety of tissues

  10. Results indicated that FAIM2 beta-isoform is strongly expressed in breast tumour tissues. Fas sensitivity was reduced in the MCF10A breast cells expressing the FAIM2 beta-isoform.

  11. This study highlighted the importance of two candidate genes, SH2B1 and FAIM2, in the risk of overweight/obesity.

  12. A polymorphism in FAIM2 is associated with higher myocardial infarction risk in type-2 diabetes mellitus subjects.

  13. The rs7138803 variant of FAIM2 was found to exert no effect on obesity in a Chinese Han population.

  14. Faim2 is physiologically expressed in brain in bacterial meningitis.

  15. Analysis identified SNPs at three loci known to be associated with BMI with genome-wide confidence (P<5x10(-8); FTO, MC4R and FAIM2).

  16. LFG is required for proper development and survival of granular and Purkinje cells and LFG may play a role in cerebellar disorders

  17. LFG is strongly expressed in breast cancer epithelial cells. Moreover, the overexpression of LFG correlated with tumour grade and reduced Fas sensitivity.

  18. Data show that SNPs in SEC16B and TMEM18 were significantly associated with obesity, and the SNPs in GNPDA2, BDNF, FAIM2 and MC4R were marginally associated with obesity in Japanese.

  19. Human keratinocytes were transfected with either Flip, Faim, or Lifeguard (LFG). Our results suggest that heterotopic expression of antiapoptotic proteins can induce the resistance of keratinocytes to a major mechanism of rejection.

  20. The tmbim2 may participate in cell death regulation by interacting with proteins of Bcl-2 family, promoting tumor metastasis, which is deduced from the evolutionary conservation of the membrane protein family containing multiple membrane spanning segments

Mouse (Murine) Fas Apoptotic Inhibitory Molecule 2 (FAIM2) Interaktionspartner

  1. that FAIM2 is an intrinsic neuroprotective factor activated by stress in photoreceptors and delays FAS-mediated photoreceptor apoptosis

  2. Increased degeneration of dopaminergic neurons was found in animals with Faim2 deficiency.

  3. MiR-3202 can promote EC apoptosis in hyperglycemic conditions, which demonstrated that EC apoptosis induced by high-glucose conditions partly depends on miR-3202 targeting FAIM2.

  4. LFG plays a role in protecting T cells from apoptosis during antiviral immune response.

  5. Data suggest Faim2/LFG (lifeguard protein) protects against FasL-/Fas ligand-induced apoptosis by down-regulating calcium release from endoplasmic reticulum in cortical neurons.

  6. In Faim2-deficient mice, there was increased hippocampal cell death during acute bacterial meningitis.

  7. Expression of Faim2 is triggered, at least in part, by Fas-receptor activation and subsequent ERK signaling.

  8. mechanism of action of LFG as an inhibitor of the Fas pathway and evidence of the neuroprotective role of LFG in cerebellar granule neurons and Purkinje cells in an organotypic cerebellar culture system

  9. This study demonistrated that lack of Faim2 caused an increase in susceptibility to combined oxygen-glucose deprivation in primary neurons as well as in caspase-associated cell death, stroke volume, and neurological impairment after cerebral ischemia.

  10. LFG is an endogenous inhibitor of FasL-mediated neuronal death detected in lipid rafts microdomains, and it mediates the FasL resistance of CNS differentiated neurons

FAIM2 Protein Überblick

Protein Überblick

may mediate development and maintenance of the nervous system

Genbezeichner und Symbole assoziert mit FAIM2

  • Fas apoptotic inhibitory molecule 2 (FAIM2)
  • Fas apoptotic inhibitory molecule 2 (faim2)
  • Fas apoptotic inhibitory molecule 2 L homeolog (faim2.L)
  • Fas apoptotic inhibitory molecule 2a (faim2a)
  • fas apoptotic inhibitory molecule 2 (CpipJ_CPIJ015441)
  • Fas apoptotic inhibitory molecule 2 (Faim2)
  • 2900002L20Rik Protein
  • faim2 Protein
  • Lfg Protein
  • Lfg2 Protein
  • MGC84041 Protein
  • MGC146456 Protein
  • NGP35 Protein
  • NMP25 Protein
  • Nmp35 Protein
  • TMBIM2 Protein
  • zgc:110143 Protein

Bezeichner auf Proteinebene für FAIM2

Fas apoptotic inhibitory molecule 2 , protein lifeguard 2 , fas apoptotic inhibitory molecule 2 , neuromembrane protein 35 , neural membrane protein 35 , transmembrane BAX inhibitor motif-containing protein 2 , lifeguard

451885 Pan troglodytes
100196331 Salmo salar
100173980 Pongo abelii
444588 Xenopus laevis
541391 Danio rerio
779810 Xenopus (Silurana) tropicalis
6049123 Culex quinquefasciatus
23017 Homo sapiens
72393 Mus musculus
246274 Rattus norvegicus
426899 Gallus gallus
477613 Canis lupus familiaris
509790 Bos taurus
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