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may mediate development and maintenance of the nervous system [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen FAIM2 Antikörper (70) und viele weitere Produktgruppen zu diesem Protein an.
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Human FAIM2 Protein expressed in Wheat germ - ABIN1353388
Müller, Maurer, Reimers, Vogt, Bucan: TRIM21, a negative modulator of LFG in breast carcinoma MDA-MB-231 cells in vitro. in International journal of oncology 2015
that miR (zeige MLXIP Proteine)-193b is indispensible for the competitive endogenous RNA role of SNHG7 in FAIM2-supported tumourigenesis of lung cancer
FAIM2 expression is significantly downregulated in human masticatory mucosa during wound healing
our research showed that lncRNA-SNHG7 promotes the proliferation, migration and invasion, and inhibits apoptosis of lung cancer cells by enhancing the FAIM2 expression, suggesting that lncRNA-SNHG7 as a key regulator of gene expression, may be a promising therapeutic strategy for the treatment of lung cancer
The interaction of TRIM21 (zeige TRIM21 Proteine) and LFG was analyzed by co-immunoprecipitation. To examine changes in regulatory processes, western blot analyses, real-time PCR, activity of apoptotic process and flow cytometric analyses were carried out.
There are significant differences in the associations of the FAIM2 promoter methylation with sedentary behaviour and physical activity between obese and lean children.
Methylation levels of the FAIM2 promoter are significantly associated with obesity and are independently associated with dyslipidaemia and its components in Chinese children.
Low KRT13 (zeige KRT13 Proteine) mRNA expression is associated with oral squamous cell carcinoma.
These results suggest that the TMBIM family has comparable functions in the maintenance of intracellular Ca(2 (zeige CA2 Proteine)) homeostasis in a wide variety of tissues
Results indicated that FAIM2 beta-isoform is strongly expressed in breast tumour tissues. Fas (zeige FAS Proteine) sensitivity was reduced in the MCF10A breast cells expressing the FAIM2 beta-isoform.
This study highlighted the importance of two candidate genes, SH2B1 (zeige SH2B1 Proteine) and FAIM2, in the risk of overweight/obesity.
that FAIM2 is an intrinsic neuroprotective factor activated by stress in photoreceptors and delays FAS (zeige FAS Proteine)-mediated photoreceptor apoptosis
Increased degeneration of dopaminergic neurons was found in animals with Faim2 deficiency.
MiR (zeige MLXIP Proteine)-3202 can promote EC apoptosis in hyperglycemic conditions, which demonstrated that EC apoptosis induced by high-glucose conditions partly depends on miR (zeige MLXIP Proteine)-3202 targeting FAIM2.
LFG plays a role in protecting T cells from apoptosis during antiviral immune response.
Data suggest Faim2/LFG (lifeguard protein) protects against FasL-/Fas ligand (zeige FASL Proteine)-induced apoptosis by down-regulating calcium release from endoplasmic reticulum in cortical neurons.
In Faim2-deficient mice, there was increased hippocampal cell death during acute bacterial meningitis.
Expression of Faim2 is triggered, at least in part, by Fas-receptor (zeige FAS Proteine) activation and subsequent ERK (zeige EPHB2 Proteine) signaling.
mechanism of action of LFG as an inhibitor of the Fas (zeige FAS Proteine) pathway and evidence of the neuroprotective role of LFG in cerebellar granule neurons and Purkinje cells in an organotypic cerebellar culture system
This study demonistrated that lack of Faim2 caused an increase in susceptibility to combined oxygen-glucose deprivation in primary neurons as well as in caspase (zeige CASP3 Proteine)-associated cell death, stroke volume, and neurological impairment after cerebral ischemia.
LFG is an endogenous inhibitor of FasL (zeige FASL Proteine)-mediated neuronal death detected in lipid rafts microdomains, and it mediates the FasL (zeige FASL Proteine) resistance of CNS differentiated neurons
may mediate development and maintenance of the nervous system
Fas apoptotic inhibitory molecule 2
, protein lifeguard 2
, fas apoptotic inhibitory molecule 2
, neuromembrane protein 35
, neural membrane protein 35
, transmembrane BAX inhibitor motif-containing protein 2