anti-Fanconi Anemia, Complementation Group L (FANCL) Antikörper

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). Zusätzlich bieten wir Ihnen FANCL Kits (4) und FANCL Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
FANCL 55120 Q9NW38
FANCL 67030 Q9CR14
FANCL 305600  
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Top anti-FANCL Antikörper auf antikoerper-online.de

Showing 10 out of 69 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Hund Kaninchen Unkonjugiert IHC, WB <b>WB Suggested Anti-FANCL Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:62500<br><b>Positive Control: </b>Human heart 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Ziege Unkonjugiert ELISA, WB 0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$481.25
Details
Human Ziege Unkonjugiert ELISA, WB Western Blot: FANCL Antibody [NBP1-49839] - Analysis of FANCL in Human Bone Marrow lysate (35ug protein in RIPA buffer) NBP1-49839 at 1 ug/ml. Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
$485.88
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: FANCL Antibody [NBP1-84758] - Lane 1: Marker [kDa] 230, 130, 95, 72, 56, 36, 28, 17, 11.Lane 2: Human cell line RT-4.Lane 3: Human cell line U-251MG sp Immunohistochemistry-Paraffin: FANCL Antibody [NBP1-84758] - Staining of human duodenum shows strong membranous and cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 7 bis 9 Tage
$491.63
Details
Human Kaninchen Unkonjugiert IF, IP, WB FANCL MaxPab rabbit polyclonal antibody. Western Blot analysis of FANCL expression in human spleen. FANCL MaxPab rabbit polyclonal antibody. Western Blot analysis of FANCL expression in A-431. 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Fledermaus Ziege Unkonjugiert ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$610.50
Details
Human Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB FANCL Antibody (C-term) (ABIN1881336) western blot analysis in 293 cell line lysates (35 µg/lane). This demonstrates the FANCL antibody detected the FANCL protein (arrow). 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$335.50
Details
Human Kaninchen Unkonjugiert IF, WB Western Blot analysis of FANCL expression in transfected 293T cell line by FANCL MaxPab polyclonal antibody.<br><br>Lane 1: FANCL transfected lysate(42.90 KDa).<br>Lane 2: Non-transfected lysate.<br> FANCL MaxPab rabbit polyclonal antibody. Western Blot analysis of FANCL expression in human spleen. 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
$425.71
Details
Human Maus Unkonjugiert WB Western Blot analysis of FANCL expression in transfected 293T cell line by FANCL MaxPab polyclonal antibody.<br><br>Lane 1: FANCL transfected lysate(41.25 KDa).<br>Lane 2: Non-transfected lysate.<br> 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details

FANCL Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
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Mouse (Murine)
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Rat (Rattus)
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Am meisten referenzierte anti-FANCL Antikörper

  1. Human Polyclonal FANCL Primary Antibody für WB - ABIN1881336 : Zhang, Zhao, Park, Wang, Dyer, Liu, Klee, McNiven, Tindall, Molina, Fei: FAVL elevation in human tumors disrupts Fanconi anemia pathway signaling and promotes genomic instability and tumor growth. in The Journal of clinical investigation 2010 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal FANCL Primary Antibody für IHC, IHC (p) - ABIN4310524 : Panneerselvam, Pickering, Han, Li, Zheng, Zhang, Zhang, Fei: Basal level of FANCD2 monoubiquitination is required for the maintenance of a sufficient number of licensed-replication origins to fire at a normal rate. in Oncotarget 2014 (PubMed)

  3. Human Polyclonal FANCL Primary Antibody für ELISA, WB - ABIN4310523 : García, Fernández, Osorio, Barroso, Fernández, Urioste, Benítez et al.: Mutational analysis of FANCL, FANCM and the recently identified FANCI suggests that among the 13 known Fanconi Anemia genes, only FANCD1/BRCA2 plays a major role in high-risk breast cancer ... in Carcinogenesis 2009 (PubMed)

Weitere Antikörper gegen FANCL Interaktionspartner

Human Fanconi Anemia, Complementation Group L (FANCL) Interaktionspartner

  1. A novel homozygous mutation c.822_823insCTTTCAGG (p.Asp275LeufsX13) in the FANCL gene identified in a Chinese patient with Fanconi anemia (zeige PALB2 Antikörper).

  2. Using small interfering RNA (siRNA), knockdown of FANCF (zeige FANCF Antikörper), FANCL, or FANCD2 (zeige FANCD2 Antikörper) inhibited function of the FA/BRCA pathway in A549, A549/DDP (zeige TIMM8A Antikörper) and SK-MES (zeige ME1 Antikörper)-1 cells, and potentiated sensitivity of the three cells to cisplatin.

  3. Loss-of-Function FANCL Mutations Associate with Severe Fanconi Anemia (zeige PALB2 Antikörper) Overlapping the VACTERL Association

  4. a signal transduction pathway involved in self-renewal and survival of hematopoietic stem cells also functions to stabilize FANCL and suggesting that FANCL participates directly in support of stem cell function.

  5. Suppression of FANCL expression in normal CD34(+) stem and (zeige CTNNB1 Antikörper)progenitor cells results in fewer beta-catenin active cells and inhibits expansion of multilineage progenitors.

  6. FA DNA repair genes, FANCD2 (zeige FANCD2 Antikörper), FANCL, and FANCC (zeige FANCC Antikörper), are transcriptionally upregulated differently in melanoma compared with non-melanoma skin cancer

  7. genetic diversity in FANCA (zeige FANCA Antikörper), FANCC (zeige FANCC Antikörper) and FANCL does not support an association of these genes with cervical cancer susceptibility in the Swedish population.

  8. FANCL is associated with acute lung injury in mice

  9. expression of a novel splice variant of FA complementation group L (FANCL), named FAVL, can impair the FA pathway in non-FA tumor cells and act as a tumor promoting factor

  10. data suggest that PHF9 has a crucial role in the Fanconi anemia (zeige PALB2 Antikörper) pathway as the likely catalytic subunit required for monoubiquitination of FANCD2 (zeige FANCD2 Antikörper)

Mouse (Murine) Fanconi Anemia, Complementation Group L (FANCL) Interaktionspartner

  1. The authors report the structure of the human FANCL central domain and show that the RING domain is necessary and sufficient for E2 binding.

  2. Using HeLa cells and lymphoblasts from Fanconi anemia (zeige PALB2 Antikörper) patients, the authors characterize PHF9 (FANCL) as a ubiquitin ligase (zeige RNF123 Antikörper) and show it is essential for FANCD2 (zeige FANCD2 Antikörper) monoubiquitination. The authors state that PHF9 is the human homolog of mouse Pog (Fancl).

  3. FANCL increases the activity and expression of beta-catenin (zeige CTNNB1 Antikörper), a key pluripotency factor in hematopoietic stem cells.

  4. UBE2W (zeige UBE2W Antikörper) regulates FANCD2 (zeige FANCD2 Antikörper) monoubiquitination by mechanisms different from UBE2T (zeige Ube2t Antikörper) and HRR6.

  5. Fancl is associated with acute lung injury

  6. expression of a novel splice variant of FA complementation group L (FANCL), named FAVL, can impair the FA pathway in non-FA tumor cells and act as a tumor promoting factor

  7. Deletion of Pog causes germ cell deficiency, but is also accompanied by reduced embryonic body weight and sometimes lethality.

  8. GGN1 and GGN3, interacted with POG, regulated the localization of POG, and played a role in spermatogenesis.

  9. unlike in POG-deficient females, the germ cells in POG-deficient males eventually populate the seminiferous tubules at 9 wk, and fertility can be achieved by 12 wk.

FANCL Antigen-Profil

Protein Überblick

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity\; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group L. Alternative splicing results in two transcript variants encoding different isoforms.

Genbezeichner und Symbole assoziert mit FANCL

  • Fanconi anemia complementation group L (FANCL) Antikörper
  • Fanconi anemia, complementation group L (Fancl) Antikörper
  • 2010322C19Rik Antikörper
  • AW554273 Antikörper
  • B230118H11Rik Antikörper
  • FAAP43 Antikörper
  • gcd Antikörper
  • Phf9 Antikörper
  • Pog Antikörper

Bezeichner auf Proteinebene für FANCL

E3 ubiquitin-protein ligase FANCL , PHD finger protein 9 , fanconi anemia group L protein , fanconi anemia-associated polypeptide of 43 kDa , fanconi anemia group L protein homolog , germ cell deficient , proliferation of germ cells protein

GENE ID SPEZIES
55120 Homo sapiens
612161 Canis lupus familiaris
614512 Bos taurus
67030 Mus musculus
305600 Rattus norvegicus
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