F-Box and WD Repeat Domain Containing 11 Proteine (FBXW11)

FBXW11 encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box.

alle Proteine anzeigen Gen GeneID UniProt
Ratte FBXW11 FBXW11 303024  
Human FBXW11 FBXW11 23291 Q9UKB1
Maus FBXW11 FBXW11 103583 Q5SRY7
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
$8,498.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
$814.00
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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Weitere Proteine zu F-Box and WD Repeat Domain Containing 11 (FBXW11) Interaktionspartnern

Human F-Box and WD Repeat Domain Containing 11 (FBXW11) Interaktionspartner

  1. SCF(FBXW11) bound, polyubiquitylated, and destabilized RAPGEF2, a guanine nucleotide exchange factor that activates the small GTPase RAP1

  2. Data indicate that miR (zeige MLXIP Proteine)-106b-25 cluster (miR (zeige MLXIP Proteine)-106b, miR (zeige MLXIP Proteine)-93 and miR (zeige MLXIP Proteine)-25) targets the 3'UTR of the beta-TRCP2 transcript and increases the expression of Snail (zeige SNAI1 Proteine).

  3. Knockdown of beta-TrCP1 (zeige BTRC Proteine) and beta-TrCP2 attenuated the K48-linked ubiquitination and degradation of IRAK1 (zeige IRAK1 Proteine).

  4. two splice variants of beta-transducin repeat containing protein 2 (BTRCP2) localise exclusively to either the nucleus or the cytosol.

  5. Data indicate that knockdown of beta-TrCP1 and beta-TrCP2 markedly reduced IL-17-induced, phosphorylation-dependent ubiquitination and degradation of Act1.

  6. FBXW11 may be the most likely candidate gene for the Holoprosencephaly and prexial polydactyly phenotype.

Mouse (Murine) F-Box and WD Repeat Domain Containing 11 (FBXW11) Interaktionspartner

  1. The mTOR pathway promotes cell proliferation via beta-TrCP2-dependent p19(Arf) degradation under nutrient-rich conditions.

  2. Data show that beta-TrCP2 and beta-TrCP1 (zeige BTRC Proteine) target PER2 (zeige PER2 Proteine) protein in vitro, and also show that the beta-TrCP (zeige BTRC Proteine) binding site of PER2 (zeige PER2 Proteine) is recognized by both beta-TrCP1 (zeige BTRC Proteine) and beta-TrCP2 [beta-TrCP2].

FBXW11 Protein Überblick

Protein Überblick

This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbws class and, in addition to an F-box, contains multiple WD40 repeats. This gene contains at least 14 exons, and its alternative splicing generates 3 transcript variants diverging at the presence/absence of two alternate exons.

Genbezeichner und Symbole assoziert mit FBXW11

  • F-box and WD repeat domain containing 11 (Fbxw11)
  • F-box and WD repeat domain containing 11 (FBXW11)
  • F-box/WD repeat-containing protein 11 (LOC100199403)
  • F-box and WD-40 domain protein 11 (Fbxw11)
  • F-box and WD repeat domain containing 11b (fbxw11b)
  • 2310065A07Rik Protein
  • AA536858 Protein
  • btrc2 Protein
  • BTRCP2 Protein
  • FBW1B Protein
  • Fbw11 Protein
  • Fbxw1b Protein
  • fbxw11a Protein
  • HOS Protein
  • wu:fa12e12 Protein
  • wu:fb11f03 Protein
  • zgc:63728 Protein

Bezeichner auf Proteinebene für FBXW11

F-box/WD repeat-containing protein 11 , F-box and WD-40 domain protein 11 , F-box and WD repeat domain containing 11 , f-box/WD repeat-containing protein 11-like , F-box and WD repeats protein beta-TrCP2 , F-box and WD-40 domain protein 1B , F-box protein Fbw1b , F-box/WD repeat-containing protein 1B , beta-transducin repeat-containing protein 2 , homologous to Slimb protein , fbxw11

GENE ID SPEZIES
303024 Rattus norvegicus
462263 Pan troglodytes
708990 Macaca mulatta
100069972 Equus caballus
100199403 Hydra magnipapillata
100217770 Taeniopygia guttata
100402300 Callithrix jacchus
100479018 Ailuropoda melanoleuca
100605260 Nomascus leucogenys
23291 Homo sapiens
416181 Gallus gallus
479291 Canis lupus familiaris
540642 Bos taurus
100340737 Oryctolagus cuniculus
100715997 Cavia porcellus
101107136 Ovis aries
103583 Mus musculus
406825 Danio rerio
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