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EFNA2 encodes a member of the ephrin family.
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The ephrin-A2/-A3 DKO mice have utility as a novel ASD (zeige GUSB ELISA Kits) model with an emphasis on sensory abnormalities and restricted, repetitive behavioral symptoms.
The results of this study suggested that majority of the changes observed ephrin-A2 and ephrin-A5 (zeige EFNA5 ELISA Kits) KO mice appear to be mediated by the effects on motor neurons and their muscle targets, rather than changes in auditory sensitivity.
Ephrin-A2 and -A3 are negative regulators of the proliferative and neurogenic potentials of Muller cells.
Ephrin-A2 and Ephrin-A5 (zeige EFNA5 ELISA Kits) are important for the functional development of cutaneous innervation.
At high frequencies, the ephrin-A2A5(-/-) mice exhibited thresholds that were significantly lower than in wild-type mice by approximately 20 dB, suggesting ephrin-A2 and ephrin-A5 (zeige EFNA5 ELISA Kits) may have frequency-specific effects on the auditory system.
In EphA4 (zeige EPHA4 ELISA Kits) mutant mice, as well as after ephrin A2 knockdown using in utero electroporation, we found delayed interneuron migration at embryonic stages.
ephrin-A2 regulates experience-dependent, NMDA receptor-mediated synaptic pruning through glial glutamate (zeige GRIN1 ELISA Kits) transport during maturation of the mouse cortex.
EphA2 (zeige EPHA2 ELISA Kits)-mediated mesenchymal-amoeboid transition induced by endothelial progenitor cells enhances metastatic spread due to cancer-associated fibroblasts.
Implicate EphA2 (zeige EPHA2 ELISA Kits) as a novel proinflammatory mediator and potential regulator of atherosclerotic plaque development.
The results of this study suggested that the misexpression of ephrin-A2 may lead to abnormal connectivity in regions known for their involvement in reversal learning and perseverative behaviours.
Ephrin-A2 expression was correlated with Ki-67 (zeige MKI67 ELISA Kits) expression in PCa patients, both at the gene scale and protein level. Our data indicate that Ephrin-A2 is a potential diagnostic and prognostic biomarker and a promising molecular therapeutic target to attenuate prostate cancer progression
these studies suggested that Kaposi's sarcoma-associated herpesvirus utilizes CIB1 (zeige CIB1 ELISA Kits) as one of the key molecule(s) to coordinate and sustain the EphA2 (zeige EPHA2 ELISA Kits) mediated signaling involved in its entry
High EphA2 (zeige EPHA2 ELISA Kits) receptor expression in colorectal cancer was associated with a worse outcome in patients treated with cetuximab-based therapy
Ephrin A1 (zeige EFNA1 ELISA Kits) promotes the motility of EphA2 (zeige EPHA2 ELISA Kits)-positive cardiac stem cells, facilitates their migration to the area of damage, and enhances cardiac repair
Optic nerve section in adult rat differentially regulates the expression of ephrin-A2 in the superior colliculus(SC).At 1 month, levels were upregulated across the contralateral SC giving rise to an increasing rostro-caudal (zeige CAD ELISA Kits) gradient.
Different forms of Elf-1 are the products of posttranslational modifications that determine its subcellular localization, activity, and metabolic degradation.
Abnormal posttranslational mechanisms of the Elf-1 protein result in defective expression of the functional 98-kDa form of Elf-1, and consequently, the transcriptional defect of TCR zeta-chain (zeige CD247 ELISA Kits) in patients with systemic lupus erythematosus.
There is a significant loss of ELF-1 and reduced Smad4 (zeige SMAD4 ELISA Kits) expression in gastrointestinal neoplasms.
Elf-1 represents the first transcription factor identified to be involved in the transcriptional regulation of Fc receptor (zeige FCGRT ELISA Kits) gamma
This gene encodes a member of the ephrin family. The protein is composed of a signal sequence, a receptor-binding region, a spacer region, and a hydrophobic region. The EPH and EPH-related receptors comprise the largest subfamily of receptor protein-tyrosine kinases and have been implicated in mediating developmental events, particularly in the nervous system. Based on their structures and sequence relationships, ephrins are divided into the ephrin-A (EFNA) class, which are anchored to the membrane by a glycosylphosphatidylinositol linkage, and the ephrin-B (EFNB) class, which are transmembrane proteins. Posttranslational modifications determine whether this protein localizes to the nucleus or the cytoplasm.
, EPH related receptor tyrosine kinase ligand 6
, EPH-related receptor tyrosine kinase ligand 6
, ephrin A6
, ephrin A-2
, HEK7 ligand
, eph-related receptor tyrosine kinase ligand 6
, Eph ligand family-1