Early B-Cell Factor 3 Proteine (EBF3)

EBF3 encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. Zusätzlich bieten wir Ihnen EBF3 Antikörper (39) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
EBF3 13593 O08791
EBF3 253738 Q9H4W6
Ratte EBF3 EBF3 361668  
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Showing 4 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 60 Days
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 10 bis 12 Tage

EBF3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Mouse (Murine)

Human , ,
, ,

Weitere Proteine zu Early B-Cell Factor 3 (EBF3) Interaktionspartnern

Mouse (Murine) Early B-Cell Factor 3 (EBF3) Interaktionspartner

  1. Our findings highlight the critical role of Ebf3 in multipolar-to-bipolar transition via positive feedback regulation of NeuroD1 in the developing neocortex.

  2. EB3 (zeige MAPRE3 Proteine) binds to IP3 receptors, promotes IP3R (zeige ITPR1 Proteine) clustering and Ca2 (zeige CA2 Proteine)+ signals in endothelial cells.

  3. Ebf3 is a new regulator of terminal muscle differentiation in the diaphragm, and Ebf (zeige EBF1 Proteine) factors cooperate with MyoD (zeige MYOD1 Proteine) in the induction of muscle-specific (zeige EIF3K Proteine) genes

  4. The regulation of Ebf3 expression by miR218 controls the terminal differentiation of dopaminergic neurons.

  5. MAP1B (zeige MAP1B Proteine) interacts directly with EB1 (zeige MAPRE1 Proteine) and EB3 (zeige MAPRE3 Proteine) (EBs), two core 'microtubule plus-end tracking proteins' ( TIPs), and sequesters them in the cytosol of developing neuronal cells.

  6. Ebf2 (zeige EBF2 Proteine) and Ebf3, singly or together, control the migration of Cajal-Retzius cells arising in the cortical hem. These findings provide evidence that Ebfs directly regulate Cajal-Retzius cell development

  7. DDA3 (zeige PSRC1 Proteine) is a novel microtubule-associated protein (zeige SPAG5 Proteine) that binds to EB3 (zeige MAPRE3 Proteine), and results implicate DDA3 (zeige PSRC1 Proteine) and EB3 (zeige MAPRE3 Proteine) in the beta-catenin (zeige CTNNB1 Proteine)-mediated growth signaling.

  8. Two +TIPs, CLIP-170 and end-binding protein 3 (EB3 (zeige MAPRE3 Proteine)), turn over rapidly on MT ends. Diffusion of CLIP-170 and EB3 (zeige MAPRE3 Proteine) appears to be rate limiting for their binding to MT plus ends.

Zebrafish Early B-Cell Factor 3 (EBF3) Interaktionspartner

  1. Data revealed that expression of DNA binding inhibitor 3, early B cell factor 2, Ebf3, Iroquois related homeobox 1, Kruppel-like factor 7 , mab-21-like 1 , fatty acid binding protein 7 and stathmin-like 4,were enriched in the diencephalon of zebrafish.

Human Early B-Cell Factor 3 (EBF3) Interaktionspartner

  1. In 11 affected individuals from 11 unrelated families, we identified de novo variants in EBF3 (zeige MAPRE3 Proteine) as potentially causative for the neurodevelopmental phenotype. The variants include one nonsense, two frameshift deletions, one splice, and three missense variants. There are three de novo missense variants, (p.(Lys64Thr), p.(His157Gln), and p.(Arg209Gln), which are all in the COE1 (zeige EBF1 Proteine) DNA-binding domain.

  2. EBF3 (zeige MAPRE3 Proteine), a transcription factor previously unknown to be associated with human disease, is important for brain and other organ development and warrants further investigation

  3. findings indicate that mutations in EBF3 cause a genetic neurodevelopmental syndrome and suggest that loss of EBF3 function might mediate a subset of neurologic phenotypes shared by ARX-related disorders, including intellectual disability, abnormal genitalia, and structural CNS malformations

  4. findings demonstrate that variants disrupting EBF3 (zeige MAPRE3 Proteine)-mediated transcriptional regulation cause intellectual disability and developmental delay and are present in approximately 0.1% of individuals with unexplained neurodevelopmental disorders

  5. Early B-cell factor 3 (EBF3) is a novel tumor suppressor gene with promoter hypermethylation in pediatric acute myeloid leukemia (zeige BCL11A Proteine)

  6. EBF3 (zeige MAPRE3 Proteine) tumor suppressor is epigenetically silenced and that it serves as an independent prognostic marker in gastric carcinoma.

  7. Results verify IRX1 (zeige IRX3 Proteine), EBF3 (zeige MAPRE3 Proteine), SLC5A8, SEPT9 (zeige SEPT9 Proteine), and FUSSEL18 as valid methylation markers in two separate sets of HNSCC specimens; also preliminarily show a trend between HPV16 positivity and target gene hypermethylation of IRX1 (zeige IRX3 Proteine), EBF3 (zeige MAPRE3 Proteine), SLC5A8, and SEPT9 (zeige SEPT9 Proteine).

  8. Findings suggested that the transfection of EBF3 (zeige MAPRE3 Proteine) gene into HepG2 induced the cell proliferation from G1 phase to G2 phase by increasing the number of cells.

  9. Expression of EBF3 resulted in cell cycle arrest and apoptosis. EBF3 regulates a transcriptional program underlying a putative tumor suppression pathway.

  10. Frequent methylation of EBF3 (zeige MAPRE3 Proteine) gene is associated with head and neck squamous cell carcinoma

EBF3 Protein Überblick

Protein Überblick

This gene encodes a member of the early B-cell factor (EBF) family of DNA binding transcription factors. EBF proteins are involved in B-cell differentiation, bone development and neurogenesis, and may also function as tumor suppressors. The encoded protein inhibits cell survival through the regulation of genes involved in cell cycle arrest and apoptosis, and aberrant methylation or deletion of this gene may play a role in multiple malignancies including glioblastoma multiforme and gastric carcinoma.

Genbezeichner und Symbole assoziert mit Early B-Cell Factor 3 Proteine (EBF3)

  • early B cell factor 3 (Ebf3)
  • early B-cell factor 3 (EBF3)
  • early B-cell factor 3 (Ebf3)
  • early B-cell factor 3 L homeolog (ebf3.L)
  • early B-cell factor 3a (ebf3a)
  • early B-cell factor 3 (ebf3)
  • 3110018A08Rik Protein
  • coe3 Protein
  • EBF-3 Protein
  • EBF3 Protein
  • mKIAA4201 Protein
  • O/E-2 Protein
  • OE-2 Protein
  • oe2 Protein
  • Xcoe3 Protein
  • xebf-3 Protein
  • Xebf3 Protein
  • zgc:158829 Protein

Bezeichner auf Proteinebene für Early B-Cell Factor 3 Proteine (EBF3)

EBF-3 , OE-2 , Olf-1/EBF-like 2 , early B-cell factor 3 , transcription factor COE3 , olf-1/EBF-like 2 , xOE-2 , LOW QUALITY PROTEIN: transcription factor COE3

13593 Mus musculus
253738 Homo sapiens
361668 Rattus norvegicus
395175 Gallus gallus
399125 Xenopus laevis
567751 Danio rerio
737690 Pan troglodytes
100135240 Xenopus (Silurana) tropicalis
611743 Canis lupus familiaris
100732902 Cavia porcellus
Ausgewählte Anbieter für EBF3 Proteine (EBF3)
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