anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antikörper

Probably involved in mitochondrial protein import. Zusätzlich bieten wir Ihnen DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Kits (54) und DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Proteine (20) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNAJB1 3337 P25685
DNAJB1 361384  
DNAJB1 81489 Q9QYJ3
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen
  • orders@antikoerper-online.de

Top anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Antikörper auf antikoerper-online.de

Showing 10 out of 391 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert IHC, WB DNAJB1 antibody - N-terminal region (ARP54795_P050) Catalog Number: ARP54795_P050  Formalin Fixed Paraffin Embedded Tissue: Human Lung Tissue  Observed Staining: Nucleus of pneumocytes Primary Antibody Concentration: 1:100  Secondary Antibody: Donkey anti-Rabbit-Cy3  Secondary Antibody Concentration: 1:200  Magnification: 20X  Exposure Time: 0.5 - 2.0 sec WB Suggested Anti-DNAJB1 Antibody Titration: 0.2-1 ug/ml ELISA Titer: 1:1562500 Positive Control: 721_B cell lysate 100 μL 2 bis 3 Tage
$319.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 100 μL 2 bis 3 Tage
$289.00
Details
Plasmodium falciparum Kaninchen Unkonjugiert ICC, IF, WB Hsp40 (Pf11_01513), malarial parasite lysate. 100 μg 3 bis 4 Tage
$453.70
Details
Yeast Maus Unkonjugiert IP, ELISA, WB Hsp40 (YDJ1 2A7 H6), 0. 100 μg 3 bis 4 Tage
$445.90
Details
Plasmodium falciparum Kaninchen FITC ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$504.40
Details
Plasmodium falciparum Kaninchen PerCP ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$513.50
Details
Plasmodium falciparum Kaninchen APC ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$513.50
Details
Plasmodium falciparum Kaninchen Atto 488 ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$514.80
Details
Plasmodium falciparum Kaninchen Atto 565 ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$514.80
Details
Plasmodium falciparum Kaninchen Atto 655 ICC, IF, WB Western blot analysis of Parasite lysates showing detection of HSP40 protein using Rabbit Anti-HSP40 Polyclonal Antibody . Primary Antibody: Rabbit Anti-HSP40 Polyclonal Antibody  at 1:2000. 100 μg 3 bis 4 Tage
$514.80
Details

Am meisten referenzierte anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Antikörper

  1. Human Polyclonal DNAJB1 Primary Antibody für IHC (p), WB - ABIN1882092 : Ohtsuka, Hata: Mammalian HSP40/DNAJ homologs: cloning of novel cDNAs and a proposal for their classification and nomenclature. in Cell stress & chaperones 2001 (PubMed)
    Show all 4 Pubmed References

  2. Human Polyclonal DNAJB1 Primary Antibody für ICC, IF - ABIN361670 : Hattori, Liu, Tohnai, Ueda, Kaneda, Kobayashi, Tanabe, Ohtsuka: Intracellular localization and partial amino acid sequence of a stress-inducible 40-kDa protein in HeLa cells. in Cell structure and function 1992 (PubMed)
    Show all 8 Pubmed References

  3. Human Monoclonal DNAJB1 Primary Antibody für FACS, IF - ABIN2719577 : Ramdzan, Polling, Chia, Ng, Ormsby, Croft, Purcell, Bogoyevitch, Ng, Gleeson, Hatters: Tracking protein aggregation and mislocalization in cells with flow cytometry. in Nature methods 2012 (PubMed)

Weitere Antikörper gegen DnaJ (Hsp40) Homolog, Subfamily B, Member 1 Interaktionspartner

Human DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Interaktionspartner

  1. Results suggest for the first time a role for miR-370 and miR-543 and its target DNAJB1 in the pathogenesis of spinocerebellar ataxia type 3 (SCA3). In human neuronal cultures derived from SCA3 patient-specific induced pluripotent stem cell (iPSC) lines, miR-370 and miR-543 levels are upregulated, while DNAJB1 expression is concurrently reduced.

  2. Overexpression of FUS or TDP-43 causes inhibition of the ubiquitin proteasome system (UPS) and toxicity, both of which are mitigated by overexpression of the Hsp40 chaperone.

  3. this study shows that DNAJB1/HSP40 suppresses Melanoma Differentiation-Associated Gene 5-Mitochondrial Antiviral Signaling Protein function in conjunction with HSP70

  4. Modeling of the different conformations of PRKACA-DNAJB1 Chimeric Kinase revealed no obvious steric interactions of the J-domain with the rest of the RIIbeta holoenzyme.

  5. Data show that DnaJ (Hsp40) homolog, subfamily B, member 1 (DNAJB1) is a transcriptional target of forkhead box protein E3 (FOXE3) in a pathway that is crucial for the development of the anterior segment of the eye.

  6. These results indicate that Mixed fibrolamellar hepatocellular carcinoma (mFL-HCC) is similar to pure FL-HCC at the genomic level and the DNAJB1:PRKACA fusion can be used as a diagnostic tool for both pure and mFL-HCC

  7. These studies demonstrate an important role for cellular chaperone Hsp40/DnaJB1 in influenza A virus life cycle by assisting nuclear trafficking of viral ribonucleoproteins.

  8. DNAJB1-PRKACA was evaluated as a key driver of fibrolamellar carcinoma and as a candidate therapeutic target

  9. siRNA experiments confirmed that a reduction in Hsp27 or Hsp40 rescued CFTR in the DeltaF508 mutant, but the rescue was not additive or synergistic with C4 + 18 treatment, indicating these correctors shared a common pathway for rescue

  10. study provides a new molecular mechanism to regulate EGFR signaling through modulation of MIG6 by DNAJB1 as a negative regulator.

  11. Whole exome sequencing followed by immunohistochemistry of fibrolamellar hepatocellular carcinoma cell lines and tumors showed two structural variants resulting in fusion transcripts: DNAJB1-PRKCA and CLPTM1L-GLIS3.

  12. In this cohort of fibrolamellar hepatocellular carcinoma, almost 80% contained the DNAJB1-PRKACA fusion transcript.

  13. Authors identified DNAJB1 as a negative regulator of PDCD5-mediated apoptosis and found that the apoptosis network of PDCD5 regulates cancer cell death.

  14. We also found that, despite an initial report to the contrary, the human homolog of Sis1, Hdj1, is capable of [PSI+] prion propagation in place of Sis1

  15. HSP40 interacts with pyruvate kinase M2 and regulates glycolysis and cell proliferation in tumor cells.

  16. Studies with specific phosphoantibodies indicate that MK5 phosphorylates Hsp40/DnaJB1 in vivo at Ser-149 or/and Ser-151 and Ser-171 in the C-terminal domain of Hsp40/DnaJB1.

  17. Results show that TDP-43 is constitutively bound to members of the Hsp40/Hsp70 family, and that heat shock-induced TDP-43 aggregation is mediated by the availability of these chaperones interacting with the inherently disordered C-terminal prion domain.

  18. Evidence supporting the presence of the DNAJB1-PRKACA chimeric transcript in 100% of the FL-HCCs examined (15/15) suggests that this genetic alteration contributes to tumor pathogenesis.

  19. we discovered a new MDM2 interacting protein, DNAJB1, and provided evidence to support its p53-dependent tumor suppressor function.

  20. we combined the Hsp70-NEF pairs with cochaperones of the J protein family (DnaJA1, DnaJA2, DnaJB1, and DnaJB4) to generate 16 permutations.

Fruit Fly (Drosophila melanogaster) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Interaktionspartner

  1. our data indicate that the MLF/DnaJ-1-dependent increase in Lz level allows the repression of Notch expression and signaling to prevent aberrant blood cell development. Thus our findings establish a functional link between MLF and the co-chaperone DnaJ-1 to control RUNX transcription factor activity and Notch signaling during blood cell development in vivo.

  2. Additional studies established that the increased toxicity upon mutating UbS2 stems from disrupting the autoprotective role that pathogenic ataxin-3 has against itself, which depends on the co-chaperone, DnaJ-1. Our data reveal a previously unrecognized balance between pathogenic and potentially therapeutic properties of the ataxin-3-Rad23 interaction; they highlight this interaction as critical for the toxicity of the S

  3. Through DnaJ-1, our data connect ataxin-3 and Rad23 to protective processes involved with protein folding rather than increased turnover of toxic polyQ species.

  4. Expression of DnaJ-1 potently suppresses alpha1ACT-dependent degeneration , concomitant with decreased aggregation of the pathogenic protein. Mutating the nuclear importer karyopherin a3 also leads to reduced toxicity from pathogenic CACNA1A

  5. HSP40 and HSP110 function together in protein homeostasis control.

  6. A high positive correlation was found between the levels of Hsp40 expression and scores of basal and induced thermotolerance, implying a significant contribution of Hsp40 gene in thermoadaptation.

Mouse (Murine) DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Interaktionspartner

  1. Study validates the DNAJB1-PRKACA fusion kinase as an oncogenic driver and candidate drug target for fibrolamellar hepatocellular carcinoma in mouse model in which tumorigenesis was significantly enhanced by genetic activation of beta-catenin.

  2. Generation of the Dnajb1-Prkaca fusion gene in wild-type mice to be sufficient to initiate formation of tumors that have many features of human fibrolamellar hepatocellular carcinonma.

  3. Overexpression of DNAJB1 relieves TDP-43 mediated toxicity in primary rodent cortical neurons.

  4. a biochemical link between Hsp40 expression and Abeta(42) proteostasis that is cell specific

  5. Hsc70, Hdj1 and Hdj2 interact with soluble and fibrillar alpha-synuclein

  6. Hsp40, which was constitutively expressed in postmeiotic spermatogenic cells in testis, was integrated into spermatozoa as two components, that is, sperm head and tail of rodent spermatozoa.

  7. function in thermotolerance

  8. HSP-40 expression was detected after 2 h of heat stress

  9. a role for Hsp40 crosstalk with CSPalpha in neuroprotection.

  10. This is a paper that uses purification techiques to find the following: Hsc40, a new member of the hsp40 family, exhibits similar expression profile to that of hsc70 in mammalian cells.

DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antigen-Profil

Protein Überblick

Probably involved in mitochondrial protein import. Is also required for efficient translocation of pre-pro-alpha-factor. Involved in heme regulation of HAP1, as a component of the high- molecular-weight (HMC) complex.

Genbezeichner und Symbole assoziert mit DNAJB1

  • DnaJ heat shock protein family (Hsp40) member B1 (DNAJB1) Antikörper
  • DnaJ heat shock protein family (Hsp40) member B1 (Dnajb1) Antikörper
  • DnaJ-like-1 (DnaJ-1) Antikörper
  • DnaJ heat shock protein family (Hsp40) member B1 (dnajb1) Antikörper
  • DnaJ (Hsp40) homolog 5 (DnaJ-5) Antikörper
  • type I HSP40 co-chaperone YDJ1 (YDJ1) Antikörper
  • DnaJ protein (dnaJ) Antikörper
  • molecular chaperone DnaJ (dnaJ) Antikörper
  • DnaJ (Hsp40) homolog, subfamily B, member 1a (dnajb1a) Antikörper
  • 0610007I11Rik Antikörper
  • anon-WO0140519.166 Antikörper
  • anon-WO0172774.135 Antikörper
  • CG10578 Antikörper
  • dhdj-1 Antikörper
  • dhdj1 Antikörper
  • dHDJ1/HSP40 Antikörper
  • Dmel\\CG10578 Antikörper
  • dnaJ Antikörper
  • dnaJ-1 Antikörper
  • DnaJ-5 Antikörper
  • DNAJ1 Antikörper
  • DnaJ1 64EF Antikörper
  • dnajb1 Antikörper
  • dnajb4 Antikörper
  • droj1 Antikörper
  • EU3500 Antikörper
  • hdj1 Antikörper
  • Hsp-40 Antikörper
  • hsp40 Antikörper
  • HSP40/HDJ1 Antikörper
  • hspf1 Antikörper
  • MAS5 Antikörper
  • RSPH16B Antikörper
  • sis1 Antikörper
  • zf-Hsp40 Antikörper
  • zgc:101068 Antikörper

Bezeichner auf Proteinebene für DNAJB1

DnaJ (Hsp40) homolog, subfmaily B, member 1 , dnaJ homolog subfamily B member 1 , dnaJ protein homolog 1 , hDj-1 , heat shock 40 kDa protein 1 , heat shock 40kD protein 1 , heat shock protein 40 , human DnaJ protein 1 , radial spoke 16 homolog B , CG10578-PA , CG10578-PB , DnaJ-1-PA , DnaJ-1-PB , Hsp40 , dnaJ like1 , Hsp40 protein , DnaJ protein , DnaJ (Hsp40) homolog, subfamily B, member 1 , DnaJ (Hsp40) homolog, subfamily B, member 1a

GENE ID SPEZIES
3337 Homo sapiens
361384 Rattus norvegicus
476688 Canis lupus familiaris
538426 Bos taurus
38643 Drosophila melanogaster
493474 Xenopus (Silurana) tropicalis
692539 Bombyx mori
855661 Saccharomyces cerevisiae S288c
1003643 Staphylococcus aureus subsp. aureus MW2
1473367 Methanosarcina acetivorans C2A
81489 Mus musculus
100713788 Cavia porcellus
445177 Danio rerio
Ausgewählte Anbieter für anti-DnaJ (Hsp40) Homolog, Subfamily B, Member 1 (DNAJB1) Antikörper
Haben Sie etwas anderes gesucht?