Dipeptidylpeptidase 10 Proteine (DPP10)

DPP10 encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. Zusätzlich bieten wir Ihnen Dipeptidylpeptidase 10 Antikörper (106) und Dipeptidylpeptidase 10 Kits (28) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
DPP10 57628 Q8N608
DPP10 269109 Q6NXK7
Ratte DPP10 DPP10 363972 Q6Q629
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Anmelden zum Anzeigen 60 bis 65 Tage
$10,699.55
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Insektenzellen Maus rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Anmelden zum Anzeigen 60 bis 65 Tage
$7,506.65
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Human Cells Human His tag 100 μg Anmelden zum Anzeigen 14 bis 16 Tage
$505.35
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Human Cells Maus His tag   50 μg Anmelden zum Anzeigen 4 Days
$522.50
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Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
$414.29
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen 11 Days
$888.80
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Escherichia coli (E. coli) Human Unkonjugiert   100 μg Anmelden zum Anzeigen 11 bis 18 Tage
$582.75
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DPP10 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , ,
Mouse (Murine) ,
,

Weitere Proteine zu Dipeptidylpeptidase 10 (DPP10) Interaktionspartnern

Human Dipeptidylpeptidase 10 (DPP10) Interaktionspartner

  1. These results show that a Dpp10 point mutation leads to increased airway responsiveness following allergen challenge.

  2. The DPP10 duplication is likely a benign CNV polymorphism enriched in Southern Chinese with a population frequency of ~1%.

  3. The stoichiometry of the Kv4.2-DPP10 complex was variable depending on the relative expression level of each subunit, with a preference for 4:2 stoichiometry

  4. the interaction of DPP10a, expressed in human atrium, with Kv4.3 channels generates a sustained current component of Ito, which may affect late repolarization phase of atrial action potentials.

  5. study suggests a genetic contribution of DPP10 rs17048175 in eosinophilic inflammation induction in the airways and to aspirin-exacerbated respiratory disease susceptibility

  6. Our results suggest that DPP10(789) is involved in the pathology of AD and other neurodegenerative diseases.

  7. demonstrated that glycosylation was necessary for both DPP10 trafficking to the cell surface and functional interaction with Kv4 channels

  8. Crystals of DPP10 obtained by the sitting-drop method were orthorhombic, belonging to space group P2(1)2(1)2(1) with unit-cell parameters a = 80.91, b = 143.73, c = 176.25 A.

  9. N-linked glycosylation of DPP10 plays an important role in modulating Kv4.3 channel/KCHIP2 complex activities.

  10. We were unable to confirm associations of single nucleotide polymorphisms of the positional candidates DPP10 and PHF11 with wheeze. Significant associations with reported and examined eczema were only observed for DPP10.

  11. Our study is the first one to provide additional evidence that supports the roles of DPP10 in influencing asthma or BHR in a Chinese population

  12. rs10208402 associated with percentage of peripheral blood eosinophils and log(e)-transformed total IgE in a Han Chinese population

  13. cloning, characterization and mapping to chromosome 2

  14. Interaction between transmembranes of DPP10/DPPX and Kv4 channel mediates functional complex formation. We call this protein DPPY, instead of DPP10, because of its revealed role as a Kv4 channel regulator.

  15. although similar in structure and sequence to other dipeptidyl peptidases, it lacks vital residues required for dipeptidyl peptidase activity and has instead evolved features that enable it to act as a component of voltage-gated potassium channels

  16. Data show that in the Kv4.2+KChIP3+DPP10 channel complex, all DPP10 variants accelerate channel gating kinetics; however, the splice variant DPP10a produces uniquely fast inactivation kinetics that accelerates with increasing depolarization.

  17. No consistent association was found between DPP10 and asthma susceptibility.

  18. REVIEW: role in health and disease

Mouse (Murine) Dipeptidylpeptidase 10 (DPP10) Interaktionspartner

  1. These results show that a Dpp10 point mutation leads to increased airway responsiveness following allergen challenge.

  2. In the presence of DPP6 or DPP10, cell surface Kv4.2 protein expression is selectively increased.

Dipeptidylpeptidase 10 (DPP10) Protein Überblick

Protein Überblick

This gene encodes a single-pass type II membrane protein that is a member of the S9B family in clan SC of the serine proteases. This protein has no detectable protease activity, most likely due to the absence of the conserved serine residue normally present in the catalytic domain of serine proteases. However, it does bind specific voltage-gated potassium channels and alters their expression and biophysical properties. Mutations in this gene have been associated with asthma. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Genbezeichner und Symbole assoziert mit Dipeptidylpeptidase 10 Proteine (DPP10)

  • dipeptidyl peptidase like 10 (DPP10)
  • dipeptidyl-peptidase 10 (inactive) L homeolog (dpp10.L)
  • dipeptidylpeptidase 10 (Dpp10)
  • dipeptidyl peptidase like 10 (Dpp10)
  • 6430601K09Rik Protein
  • DPL2 Protein
  • DPP10 Protein
  • DPP X Protein
  • DPPY Protein
  • Dprp3 Protein
  • MGC84485 Protein

Bezeichner auf Proteinebene für Dipeptidylpeptidase 10 Proteine (DPP10)

DPP X , DPRP-3 , dipeptidyl peptidase 10 , dipeptidyl peptidase IV-related protein 3 , dipeptidyl peptidase X , dipeptidyl peptidase like protein 2 , dipeptidyl peptidase-like protein 2 , inactive dipeptidyl peptidase 10 , dipeptidyl-peptidase 10 , dipeptidyl-peptidase 10 (non-functional) , KIAA1492 protein-like , DPPY , Kv4 potassium channel auxiliary subunit

GENE ID SPEZIES
57628 Homo sapiens
424280 Gallus gallus
476121 Canis lupus familiaris
617222 Bos taurus
432175 Xenopus laevis
100053255 Equus caballus
100157195 Sus scrofa
100346104 Oryctolagus cuniculus
269109 Mus musculus
363972 Rattus norvegicus
100714259 Cavia porcellus
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