Desmoglein 3 (DSG3) ELISA Kits

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Zusätzlich bieten wir Ihnen Desmoglein 3 Antikörper (175) und Desmoglein 3 Proteine (11) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
DSG3 1830 P32926
DSG3 13512  
Anti-Ratte DSG3 DSG3 291752  
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Top Desmoglein 3 ELISA Kits auf

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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Maus 0.039 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Human 7 pg/mL 28-1800 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Weitere ELISA Kits für Desmoglein 3 Interaktionspartner

Human Desmoglein 3 (DSG3) Interaktionspartner

  1. Desmoglein 3 Order and Dynamics in Desmosomes

  2. Data indicate that all 3 monoclonal antibodies (mAbs) targeted the same extracellular cadherin (EC) domain on desmoglein 3 (Dsg3), caused Dsg3 internalization in primary keratinocytes, and caused suprabasal blisters in skin.

  3. DSG3 was a key prognostic factor and predictor for neoadjuvant concurrent chemoradiotherapy response in rectal cancer patients.

  4. Treg cells exert a clear down-regulatory effect on the Dsg3-driven T-cell response and, accordingly, the formation of Dsg3-specific IgG antibodies

  5. Data identify DSG3 as a negative prognostic biomarker in resected pancreatic ductal adenocarcinoma, as high DSG3 expression is associated with poor overall survival and poor tumour-specific survival.

  6. this study directly demonstrates the occurrence of desmoglein 3 molecules outside of desmosomes and reveales that the adhesive properties of these molecules do differ depending on their localization.

  7. DSG2 (zeige DSG2 ELISA Kits) and DSG3 might be potential diagnostic markers for squamous cell carcinoma of the lung and DSG3 could be a potential differentiation marker for lung cancer.

  8. alterations of their expression suggest a role of Dsg3 and gamma-catenin (zeige JUP ELISA Kits) (additionally to E-cadherin (zeige CDH1 ELISA Kits)/beta-catenin (zeige CTNNB1 ELISA Kits)) as biomarkers of malignant transformation risk of oral dysplasia and the biological behavior (aggressiveness) of oral cancer, respectively

  9. In endometrial luminal epithelium, cadherin 6 (zeige CDH6 ELISA Kits), desmoglein 2 (zeige DSG2 ELISA Kits) and plexin b2 (zeige PLXNB2 ELISA Kits) were surprisingly found in the apical as well as the lateral membrane domain; their knock-down compromised epithelial integrity.

  10. the Dsg3 epitopes targeted by pathogenic mPV IgG are human specific in mice

Mouse (Murine) Desmoglein 3 (DSG3) Interaktionspartner

  1. Desmoglein 3 deficiency in mice leads to a phenotype characterized by cyclic alopecia in addition to the dramatic skin and mucocutaneous acantholysis observed in pemphigus patients.

  2. Dsg3, via p38 MAPK (zeige MAPK14 ELISA Kits), regulates the spatial distribution of the keratin filament network and stabilizes cell adhesion.

  3. Squamous metaplasia after pulmonary epithelial injury may play a crucial role in redirecting the skin-specific autoimmune reaction to the lungs in paraneoplastic pemphigus (PNP (zeige NP ELISA Kits)).

  4. Dsg3 deficiency results in perturbation of the desmosomal network at the transcriptional, translational, and interaction level, kinase activation, proteinase-mediated degradation, and hyper-adhesion. (Review)

  5. Thus, Dsg3 does not display a clear function as a tumor suppressor in these mouse skin cancer models

  6. IgG and IgM (zeige CD40LG ELISA Kits) antibodies against desmoglein 3 have a pathogenic role in blister formation in pemphigus vulgaris

  7. the adult passive transfer mouse model is ideally suited for detailed studies of Dsg3 antibody-mediated signaling in adult skin.

  8. These data indicate a contribution of Dsg (zeige DSG1 ELISA Kits) depletion to pemphigus vulgaris pathogenesis dependent on Ca(2 (zeige CA2 ELISA Kits)+)-induced differentiation.

  9. Transgenic expression of Dsg1 (zeige DSG1 ELISA Kits) rescued the severe B6-Dsg3(-/-) phenotype and provided a syngeneic mouse model of pemphigus vulgaris.

  10. Aire (zeige AIRE ELISA Kits) has an important role in Dsg3 expression as well as in selection of T cells that help B cells to produce anti-Dsg3 IgG in thymus.

Desmoglein 3 (DSG3) Antigen-Profil

Beschreibung des Gens

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. Desmoglein 3 is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This protein has been identified as the autoantigen of the autoimmune skin blistering disease pemphigus vulgaris.

Genbezeichner und Symbole assoziert mit Desmoglein 3 (DSG3) ELISA Kits

  • desmoglein 3 (DSG3) Antikörper
  • desmoglein 3 (Dsg3) Antikörper
  • bal Antikörper
  • balding Antikörper
  • CDHF6 Antikörper
  • DSG3 Antikörper
  • PVA Antikörper

Bezeichner auf Proteinebene für Desmoglein 3 (DSG3) ELISA Kits

desmoglein 3 (pemphigus vulgaris antigen) , desmoglein-3 , desmoglein 3 , 130 kDa pemphigus vulgaris antigen , 130-kD pemphigus vulgaris antigen , cadherin family member 6 , pemphigus vulgaris antigen , 130 kDa pemphigus vulgaris antigen homolog , desmoglein 3 preprotein

468511 Pan troglodytes
529902 Bos taurus
705685 Macaca mulatta
100347905 Oryctolagus cuniculus
100590729 Nomascus leucogenys
1830 Homo sapiens
13512 Mus musculus
291752 Rattus norvegicus
403470 Canis lupus familiaris
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