Deoxyribonuclease I (DNASE1) ELISA Kits

DNASE1 encodes a member of the DNase family. Zusätzlich bieten wir Ihnen Deoxyribonuclease I Antikörper (112) und Deoxyribonuclease I Proteine (35) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
DNASE1 1773 P24855
DNASE1 13419 P49183
DNASE1 25633 P21704
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Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 30 pg/mL 78 pg/mL - 5000 pg/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Maus 0.51 ng/mL 1.25 ng/mL - 80 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Rind (Kuh) 0.62 ng/mL 1.56 ng/mL - 100 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Ratte 0.234 ng/mL 0.391-25 ng/mL Diagramm of the ELISA kit to detect Rat DNASE1with the optical density on the x-axis and the concentration on the y-axis. 96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Kaninchen 1.0 ng/mL 10-250 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Meerschweinchen 1.0 ng/mL 10-250 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
Huhn 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Affe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Hund 1.0 ng/mL 10-250 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage

Am meisten referenzierte Deoxyribonuclease I ELISA Kits

  1. Human DNASE1 ELISA Kit für Sandwich ELISA - ABIN414564 : Dhondup, Ueland, Dahl, Askevold, Sandanger, Fiane, Ohm, Sjaastad, Finsen, Wæhre, Gullestad, Aukrust, Yndestad, Vinge: Low Circulating Levels of Mitochondrial and High Levels of Nuclear DNA Predict Mortality in Chronic Heart Failure. in Journal of cardiac failure 2016 (PubMed)

Weitere ELISA Kits für Deoxyribonuclease I Interaktionspartner

Human Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. Genetic variants in DNase I hypersensitive sites play an important role in carcinogenesis. two novel single nucleotide polymorphisms rs12309362 (odds ratio = 0.64, P = 5.61 x 10(-6) ) and rs9970827 (odds ratio = 0.73, P = 7.23 x 10(-6) ) significantly associated with decreased risk of HCC.

  2. Serum DNase1-activity is significantly decreased in ALD (zeige ABCD1 ELISA Kits) patients, indicating its potential implication in their pathogenesis. Furthermore, DNase1-activity could be used as a new surrogate biomarker for predicting response to AIH treatment.

  3. Although no significant association between Q222R polymorphism in DNAse I gene and the risk of systemic lupus erythematosus was found, the presence of the A allele was associated with an increased risk for the development of nephropathy

  4. DNase I activity was observed to be increased in type 2 diabetes, and high glucose combined with increased DNase I is suggested to aggravate beta-cell apoptosis.

  5. Single nucleotide polymorphisms producing a loss-of-function variant of the enzymes in DNASE1, DNASE1L3, and DNASE2, possibly serving as a genetic risk factor for autoimmune diseases, were confirmed.

  6. TNF-alpha (zeige TNF ELISA Kits) amplifies DNaseI expression in renal tubular cells while IL-1beta (zeige IL1B ELISA Kits) promotes nuclear DNaseI translocation in inactive form in lupus nephritis.

  7. HumDN1 polymorphisms were examined in blood of 11 worldwide populations by polymerase chain reaction. 15 genotypes were found leading to the conclusion that HumDN1 variable no. tandem repeats are ethnic group specific.

  8. Val66Met in the BDNF (zeige BDNF ELISA Kits) gene and two SNPs, Fokl and Apal, in the VDR (zeige CYP27B1 ELISA Kits) gene may potentially be associated with DED (zeige AATF ELISA Kits). Additionally, the association between DED (zeige AATF ELISA Kits) and Val66Met may vary by depression status.

  9. In conclusion, elevated DNase I in diabetes may be related to pancreatic injury and could be one of the causes that induce diabetes.

  10. Our results indicate that increased DNASE1 expression is common to both SLE and RA, while DNase1 reduction activity is specific to SLE.

Mouse (Murine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. DNase1 and DNase1-like 3 are independently expressed and thus provide dual host protection against deleterious effects of intravascular neutrophil extracellular traps.

  2. HMGN1 (zeige HMGN1 ELISA Kits) binds to CpG island-containing promoters and affects the organization of nucleosomes, DNase I hypersensitivity, and the transcriptional profile of mouse embryonic stem cells and neural progenitors.

  3. Early mesangial nephritis initiates a cascade of inflammatory signals that lead to up-regulation of Trap1 (zeige TRAP1 ELISA Kits) and a consequent down-regulation of renal DNaseI by transcriptional interference.

  4. silencing of renal DNaseI gene expression initiates a cascade of inflammatory signals including activation of Toll (zeige TLR4 ELISA Kits) like receptors and Clec4e (zeige CLEC4E ELISA Kits), leading to progression of both murine and human lupus nephritis

  5. Data show that deletion of DNaseI hypersensitive sites does not have an obvious impact on the IgH locus or B cell development.

  6. Reduction in renal Dnase1 expression and activity is limited to mice and SLE patients with signs of membranoproliferative nephritis, and may be a critical event in the development of severe forms of lupus nephritis.

  7. A conserved sequence located 211 kilobases upstream of class II major histocompatibility complex transcriptional coactivator (CIITA) promoter III is hypersensitive to DNase I.

  8. The impact of antibodies to dsDNA, renal Dnase1 and matrix metalloprotease (MMP) mRNA levels and enzyme activities on early and late events in murine lupus nephritis, was determined.

  9. serum Dnase1 in cooperation with the plasminogen (zeige PLG ELISA Kits) system guarantees a fast and effective breakdown of chromatin during necrosis by the combined cleavage of DNA as well as of DNA binding proteins.

  10. DNase I is essential for kidney injury induced by cisplatin

Cow (Bovine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. ascorbic acid has the ability to inhibit DNase I, one of the main endonucleases involved in DNA fragmentation during apoptosis.

  2. the practical capability of this assay system was successfully demonstrated by its use to determine DNase I activity in bovine urine.

  3. Specificity in DNA-DNase I interaction is mediated by DNA flexibility, which influences the induced-fit transitions required to form productive complexes.

Horse (Equine) Deoxyribonuclease I (DNASE1) Interaktionspartner

  1. Purification and characterization of equine DNase 1 was done; it was confirmed to be of the parotid-type.

Deoxyribonuclease I (DNASE1) Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the DNase family. This protein is stored in the zymogen granules of the nuclear envelope and functions by cleaving DNA in an endonucleolytic manner. At least six autosomal codominant alleles have been characterized, DNASE1*1 through DNASE1*6, and the sequence of DNASE1*2 represented in this record. Mutations in this gene have been associated with systemic lupus erythematosus (SLE), an autoimmune disease. A recombinant form of this protein is used to treat the one of the symptoms of cystic fibrosis by hydrolyzing the extracellular DNA in sputum and reducing its viscosity. Alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.

Genbezeichner und Symbole assoziert mit Deoxyribonuclease I (DNASE1) ELISA Kits

  • DNase I (endA) Antikörper
  • DNase I (LOC397802) Antikörper
  • deoxyribonuclease 1 (DNASE1) Antikörper
  • deoxyribonuclease I (Dnase1) Antikörper
  • deoxyribonuclease 1 (Dnase1) Antikörper
  • deoxyribonuclease I L homeolog (dnase1.L) Antikörper
  • deoxyribonuclease I (dnase1) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011184) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011185) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011186) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011187) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ011190) Antikörper
  • deoxyribonuclease I (CpipJ_CPIJ017803) Antikörper
  • Deoxyribonuclease I (Desal_1409) Antikörper
  • deoxyribonuclease I (MPET_RS05255) Antikörper
  • deoxyribonuclease I (METEV_RS02275) Antikörper
  • deoxyribonuclease I (Plabr_0631) Antikörper
  • AI788650 Antikörper
  • dnase1-A Antikörper
  • DNaseI Antikörper
  • Dnl1 Antikörper
  • DRNI Antikörper
  • LOC397802 Antikörper
  • zgc:92440 Antikörper

Bezeichner auf Proteinebene für Deoxyribonuclease I (DNASE1) ELISA Kits

DNase I , DNase I, lysosomal , Dornase alfa , deoxyribonuclease-1 , human urine deoxyribonuclease I , deoxyribonuclease I , Deoxyribonuclease I

8218482 Escherichia coli O157:H7 str. TW14359
397802 Xenopus laevis
1773 Homo sapiens
13419 Mus musculus
25633 Rattus norvegicus
282217 Bos taurus
394359 Xenopus laevis
395725 Gallus gallus
397051 Sus scrofa
403413 Canis lupus familiaris
436947 Danio rerio
6043536 Culex quinquefasciatus
6043537 Culex quinquefasciatus
6043538 Culex quinquefasciatus
6043539 Culex quinquefasciatus
6043542 Culex quinquefasciatus
6051839 Culex quinquefasciatus
8093039 Desulfovibrio salexigens DSM 2638
9743488 Methanoplanus petrolearius DSM 11571
100009513 Oryctolagus cuniculus
100034219 Equus caballus
9346074 Methanohalobium evestigatum Z-7303
10238020 Planctomyces brasiliensis DSM 5305
100718441 Cavia porcellus
101122154 Ovis aries
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