Defensin, beta 1 Proteine (DEFB1)

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Zusätzlich bieten wir Ihnen beta Defensin 1 Antikörper (155) und beta Defensin 1 Kits (50) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
DEFB1 1672 P60022
DEFB1 13214 P56386
DEFB1 83687 O89117
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Top beta Defensin 1 Proteine auf

Showing 10 out of 50 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Escherichia coli (E. coli) Human His tag,GST tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 20 μg Anmelden zum Anzeigen 8 bis 11 Tage
Escherichia coli (E. coli) Human Unkonjugiert   50 μg Anmelden zum Anzeigen 4 Days
Human Cells Human Fc Tag 50 μg Anmelden zum Anzeigen 20 bis 21 Tage
HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Anmelden zum Anzeigen Verfügbar
Escherichia coli (E. coli) Human His tag 50 μg Anmelden zum Anzeigen 11 Days
Escherichia coli (E. coli) Human Unkonjugiert Validation with Western Blot 10 μg Anmelden zum Anzeigen 8 bis 11 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Escherichia coli (E. coli) Human Unkonjugiert   1 mg Anmelden zum Anzeigen 2 bis 3 Tage
Escherichia coli (E. coli) Schwein Unkonjugiert SDS-PAGE analysis of Pig Defensin beta 1 Protein. 100 μg Anmelden zum Anzeigen 11 bis 18 Tage

DEFB1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , ,
, , , ,
Mouse (Murine)

Rat (Rattus)

Weitere Proteine zu Defensin, beta 1 (DEFB1) Interaktionspartnern

Human Defensin, beta 1 (DEFB1) Interaktionspartner

  1. a considerable connection of DEFB1 and TCF7L2 (zeige TCF7L2 Proteine) gene polymorphisms with nephrolithiasis

  2. identification of critical promoter regions of DEFB1 that are epigenetically influenced by lactobacilli in vaginal keratinocytes

  3. Endometrial tissues and epithelial cells constitutively secreted both BD-1 and -2 mostly at the apical compartment. Both genistein and daidzein induced BDs secretion which reached a peak at 5-15 min. The apical secretion of BDs was coincidence with increased Cl- secretion induced by genistein.

  4. The polymorphisms in DEFB1 were not associated with hBD (zeige HBd Proteine) salivary level and caries experience (p > 0.05) in children.

  5. These findings suggest a role for hBD-1 in psoriasis pathogenesis

  6. Significant associations were found between periodontitis and g. -20G> A (rs11362) and g. -44C> G (rs1800972) SNPs in DEFB1 gene as well as p.Ala29Thr (rs1126477) and p.Lys47Arg (rs1126478) SNPs in LTF (zeige LTF Proteine) gene.

  7. hBD-1 potentiates the induction of in vitro osteoclastogenesis by RANKL via enhanced phosphorylation of the p44/42 MAPKs.

  8. findings lead us to hypothesize an involvement of hBD-1 mediated innate immunity in the modulation of the susceptibility towards adeno (zeige ADORA2A Proteine)-tonsillar hypertrophy development.

  9. Two DEFB1 SNPs were significantly associated with the DMFT(decayed, missing, filled teeth) index.

  10. Multivariate logistic regression analysis showed that hBD-1 basal cell loss (>/=20% of prostatic glands in total cores) is an independent factor for predicting prostatic adenocarcinoma (odds ratio: 4.739, confidence interval: 1.093-20.554, p = 0.038). hBD-1 loss of basal cells is a useful indicator to identify extremely high-risk patients with initially negative biopsy.

Mouse (Murine) Defensin, beta 1 (DEFB1) Interaktionspartner

  1. Fenofibrate and gemfibrozil inhibit LPS (zeige TLR4 Proteine)-induced inflammatory activation of macrophages via PPARalpha (zeige PPARA Proteine)/beta-defensin 1/TLR4 (zeige TLR4 Proteine) pathway.

  2. these studies demonstrate a role for the murine beta-defensin 1 peptide in early control of Candida infection in a murine model of mucosal candidiasis

  3. Akt1 (zeige AKT1 Proteine) is involved in the regulation of defensin (zeige DEF Proteine) expression and the innate immune response important for bacterial clearance

  4. Histopathology showed a greater inflammatory influx in the lungs of mBD-1((-/-)) mice at Day 3 postinfection compared with WT C57BL/6 mice

  5. The decreased production of antimicrobial peptides by burn-site epidermal keratinocytes influenced by Gr-1 (zeige GSR Proteine)(+)CD11b (zeige ITGAM Proteine)(+) cells was shown to be restored by glycyrrhizin.

  6. elimination of mBD-1 results in a defect in the ability of the host to clear H. influenzae from the lung, which is most consistent with this peptide functioning as an antibiotic at the airway surface.

  7. The expression of BD1 was significantly elevated in the lungs of cigarette smoke-exposed mice compared with air-exposed mice.

  8. Although both murine beta-defensin (mBD)-1 and mBD2 (zeige MBD2 Proteine) are constitutively expressed in normal BALB/c and C57BL/6 corneas, mBD-1 is not required for host resistance against Pseudomonas aeruginosa-induced corneal infection.

Pig (Porcine) Defensin, beta 1 (DEFB1) Interaktionspartner

  1. pBD1 showed low hemolytic activity and high thermal stability. These properties are relevant for the biotechnological applications of the peptide.

  2. Zinc sulfate and L-isoleucine induce beta defensin expression in a porcine cell line.

  3. Presence of beta-defensin 1 in the upper respiratory tract is associated with resistance against respiratory infection with Bordetella pertussis in older piglets

beta Defensin 1 (DEFB1) Protein Überblick

Protein Überblick

Defensins form a family of microbicidal and cytotoxic peptides made by neutrophils. Members of the defensin family are highly similar in protein sequence. This gene encodes defensin, beta 1, an antimicrobial peptide implicated in the resistance of epithelial surfaces to microbial colonization. This gene maps in close proximity to defensin family member, defensin, alpha 1 and has been implicated in the pathogenesis of cystic fibrosis.

Genbezeichner und Symbole assoziert mit Defensin, beta 1 Proteine (DEFB1)

  • defensin beta 1 (DEFB1)
  • defensin beta 1 (Defb1)
  • avian beta-defensin 1 (AvBD1)
  • defensin, beta 1 (DEFB1)
  • beta-defensin 1-like (LOC100861170)
  • beta-defensin 1 (DEFB1)
  • AW260221 Protein
  • BD-1 Protein
  • BD1 Protein
  • BNBD-1 Protein
  • CBD1 Protein
  • DEFB-1 Protein
  • DEFB1 Protein
  • DEFB1-like Protein
  • DEFB101 Protein
  • HBD1 Protein
  • PBD-1 Protein
  • RHBD-1 Protein

Bezeichner auf Proteinebene für Defensin, beta 1 Proteine (DEFB1)

BD-1 , beta-defensin 1 , beta-defensin-1 , rBD-1 , Gal 1 , Gal 1-alpha , antimicrobial peptide 1 , antimicrobial peptide CHP2 , chicken heterophil peptide 2 , gal-1 alpha , gallinacin-1 alpha , cBD1 , beta defensin-1 homolog , prepro-beta-defensin 1 , Beta-defensin 1 , Defensin, beta 1 , DEFB1-like protein , beta defensin 1

1672 Homo sapiens
13214 Mus musculus
83687 Rattus norvegicus
395841 Gallus gallus
450100 Pan troglodytes
574187 Macaca mulatta
611241 Canis lupus familiaris
396819 Sus scrofa
100861170 Capra hircus
100297617 Bos taurus
103352242 Oryctolagus cuniculus
100720397 Cavia porcellus
102147207 Macaca fascicularis
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