DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) ELISA Kits

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Zusätzlich bieten wir Ihnen DNMT3B Antikörper (147) und DNMT3B Proteine (8) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
DNMT3B 1789 Q9UBC3
DNMT3B 444985  
DNMT3B 13436 O88509
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Top DNMT3B ELISA Kits auf antikoerper-online.de

Showing 4 out of 17 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Lieferzeit Preis Details
Maus 0.045 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests 13 bis 16 Tage
Human 0.112 ng/mL 0.31 ng/mL - 20 ng/mL 96 Tests 13 bis 16 Tage
Ratte 0.094 ng/mL 0.156-10 ng/mL Typical standard curve 96 Tests 12 bis 14 Tage
  96 Tests 31 bis 41 Tage

Weitere ELISA Kits für DNMT3B Interaktionspartner

Horse (Equine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation content are rather a function of time, and not a genetic component.

Cow (Bovine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.

  2. The expression levels of DNMT3a and DNMT3b were associated with several beef quality traits.

Human DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. The intronic DNMT3B rs910083-C allele (frequency=44-77%) was associated with increased risk of nicotine dependence at P=3.7 x 10-8 (odds ratio (OR)=1.06 and 95% confidence interval (CI)=1.04-1.07 for severe vs mild dependence).

  2. Chromatin immunoprecipitation coupled with loss-of-function approaches in model systems revealed common loci bound by ZBTB24 and DNMT3B, where they function to regulate gene body methylation. Genes coordinately regulated by ZBTB24 and DNMT3B are enriched for molecular mechanisms essential for cellular homeostasis, highlighting the importance of the ZBTB24-DNMT3B interplay in maintaining epigenetic patterns

  3. Level of DNMT3B expression was upregulated in breast cancer tissues and negatively correlated with the survival rate. DNMT3B is a direct target of miR-29c.

  4. DNMT3A/3B expression increases progressively from EEC to NEEC and is correlated with poor survival. The mechanisms underlying low ER/PR expression might be distinct in EEC vs. NEEC. In EEC, methylation related to DNMT3A/3B overexpression might play a major role in ER/PR downregulation.

  5. Here, we performed a comparative analysis of perturbed DNA methylation landscapes in a cohort of ICF patients using an array-based assay to (i) evaluate the similarities and differences in methylation landscapes depending on patient genotypes as an index of a functional link between the four ICF factors, (ii) identify genomic regions that rely on DNMT3B, ZBTB24, CDCA7 or HELLS for their methylation status

  6. No significant association of the SNPs on DNMT3B with Parkinson risk in a Han Chinese.

  7. High DNMT3b expression is associated with Hirschsprung disease.

  8. Dnmt3b may play a role in the tumorigenesis of mucoepidermoid carcinoma in salivary glands.

  9. Shorter overall survival was associated with BIRC5 and DNMT3B overexpression highlighting its potential as novel prognostic marker for penile cancer.

  10. results of this analysis indicating a role for DNMT3B7 in tumor progression of many additional cancer types.

  11. DNMT1 expression associated with extracapsular nodal extension. DNMT3A and DNMT3B expression showed a significant association with high histologic grade and DNMT3A expression was also associated with HER-2 status. overexpression of DNMT3B remained as an independent and unfavorable prognostic factor for disease free survival.

  12. The following meta-analysis involved only Chinese population and further confirmed the significant association of -579G>T with gastric cancer but not lung cancer and suggested no significant association between -149C>T and risk of lung or gastric cancer. Collectively, DNMT3B -579G>T polymorphism is associated with gastric cancer risk in Chinese population

  13. Among 9 candidate genes, GNB4 was identified and validated by qRT-PCR as a potential target silenced by DNA methylation via DNA methyltransferase 3B (DNMT3B).

  14. Study suggests a role for DNMT3B in leukemogenesis in inv(16) acute myeloid leukemia, through MN1 methylation regulation.

  15. Data indicate a role for DNA methyltransferase 3B (DNMT3B) suggesting that it might substitute for the absent accessory protein DNMT3L to recruit DNMT3A in somatic cells.

  16. These results provided evidence that the DNMT3B -283T>C polymorphism might significantly contribute to the lung cancer risk in the Asian population, but not the gastric cancer risk in the Chinese population.

  17. There was no significant difference in the distribution of DNMT3B -579 G>T genotypes between the cases and controls.

  18. The epigenetic targets AURKB, AURKC and DNMT3B, and the global DNA methylation profile are regulated during HIV-1 replication in CD4+ T cells, and this regulation can be influenced by the activation state of the cell at the time of infection.

  19. Data suggest that female patients carrying the rs2424932 or rs998382 variants of DNA methyltransferase 3b (DNMT3) were more likely to develop Parkinson's disease (PD) than female controls.

  20. Our study expands the mutation spectrum in ICF syndrome and supports that DNMT3B and ZBTB24 are the most common disease genes

Pig (Porcine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. The epiblast expressed epithelial markers, MUC1 and E-CADHERIN, and the pluripotency markers, DNMT3B and CRIPTO.

Mouse (Murine) DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. Loss of Dnmt3b in chondrocytes suppresses cell maturation during embryonic development.

  2. The catalytic domains of the de novo DNA methyltransferases Dnmt3a-C and Dnmt3b-C are highly homologous. Data here show for the first time that the Dnmt3a R878H mutation disrupts the cooperativity of the enzyme whereas the analogous R829H mutation in Dnmt3b-C has no effect on its processivity.

  3. These genome-wide data combined with ultra-deep locus-specific bisulfite sequencing suggest a distributive activity of ectopically expressed Dnmt3b that leads to discordant CpG island hypermethylation and provides new insights for interpreting the cancer methylome.

  4. High DNMT3b expression is associated with Hirschsprung disease.

  5. Deletion of the de novo DNA methyltransferases Dnmt3a and Dnmt3b in mouse B cells results in normal B cell development and maturation, but increased cell activation and expansion of the germinal center B cell and plasma cell populations upon immunization.

  6. this study shows that Rbm10 regulates inflammation development via alternative splicing of Dnmt3b

  7. We further demonstrated that ectopic expression of Dnmt3b in AG-haESCs could effectively improve DNA methylation level, and the high incidence of self-diploidization could be markedly rescued

  8. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1, DNMT3A, and DNMT3B proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  9. Altogether, the authors demonstrate that Dnmt3a and Dnmt3b protect the epidermis from tumorigenesis and that squamous carcinomas are sensitive to inhibition of PPAR-gamma.

  10. a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B and non-CpG methylation.

  11. Together, this study described the regulation of Chk2 expression through promoter methylation by Dnmt3b and also presented a novel role of Chk2 during neuronal differentiation, which is independent of its previously known function in DNA damage response.

  12. Mutation of all three Dnmts resulted in global genomic hypomethylation and dramatic reorganization of the photoreceptor and synaptic layers within retina. Transcriptome and proteomic analyses demonstrated enrichment of dysregulated phototransduction and synaptic genes.

  13. in mouse embryonic stem cells, Dnmt3b-dependent intragenic DNA methylation protects the gene body from spurious RNA polymerase II entry and cryptic transcription initiation

  14. three DNA methyltransferases, Dnmt1, Dnmt3a, and Dnmt3b, have been identified. Dnmt3a and Dnmt3b are responsible for establishing DNA methylation patterns produced through their de novo-type DNA methylation activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l), which is a member of the Dnmt3 family but does not possess DNA methylation

  15. While lens epithelial cell survival requires DNMT1, morphologically normal lenses develop in the absence of both DNMT3A and DNMT3B.

  16. Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.

  17. a miR-125b-DNMT3b-p53 signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.

  18. miR-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b and SET1A expression in hepatic stellate cells.

  19. Loss of DNMT3B results in hypomethylation of the miR-196b promoter and increased miR-196b expression, which directly targets the mTORC2 component Rictor.

  20. The findings define PRMT7 as a regulator of the DNMT3b/p21 axis required to maintain muscle stem cell regenerative capacity.

Zebrafish DNA (Cytosine-5-)-Methyltransferase 3 beta (DNMT3B) Interaktionspartner

  1. dnmt7 specifically methylates no tail gene in the genome

DNMT3B Antigen-Profil

Beschreibung des Gens

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.

Genbezeichner und Symbole assoziert mit DNMT3B

  • DNA methyltransferase 3 beta (DNMT3B) Antikörper
  • DNA methyltransferase 3 beta (Dnmt3b) Antikörper
  • DNA methyltransferase 3 beta (dnmt3b) Antikörper
  • DNA methyltransferase 3B (Dnmt3b) Antikörper
  • DNA (cytosine-5-)-methyltransferase 3 beta, duplicate a (dnmt3ba) Antikörper
  • cb91 Antikörper
  • DNMT3B Antikörper
  • dnmt3bl Antikörper
  • dnmt7 Antikörper
  • ICF Antikörper
  • ICF1 Antikörper
  • LOC100218113 Antikörper
  • M.HsaIIIB Antikörper
  • MmuIIIB Antikörper
  • sb:cb91 Antikörper
  • wu:fb16h07 Antikörper

Bezeichner auf Proteinebene für DNMT3B

DNA cytosine-5 methyltransferase 3 beta , DNA (cytosine-5)-methyltransferase 3B , DNA methyltransferase HsaIIIB , DNA (cytosine-5-)-methyltransferase 3 beta , DNA MTase HsaIIIB , DNA methyltransferase 3B , DNA (cytosine-5)-methyltransferase 3B-like , DNA MTase MmuIIIB , DNA methyltransferase MmuIIIB , DNA (cytosine-5-)-methyltransferase 3 beta, like , DNA (cytosine-5-)-methyltransferase 7 , fb16h07 , LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B

458174 Pan troglodytes
419287 Gallus gallus
711553 Macaca mulatta
100053900 Equus caballus
353354 Bos taurus
100218113 Taeniopygia guttata
1789 Homo sapiens
444985 Rattus norvegicus
100302109 Sus scrofa
100412936 Callithrix jacchus
100459992 Pongo abelii
100466728 Ailuropoda melanoleuca
100598378 Nomascus leucogenys
100528060 Anolis carolinensis
13436 Mus musculus
321084 Danio rerio
100731772 Cavia porcellus
100685634 Canis lupus familiaris
100349823 Oryctolagus cuniculus
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