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CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Zusätzlich bieten wir Ihnen DNMT3B Antikörper (133) und DNMT3B Proteine (9) und viele weitere Produktgruppen zu diesem Protein an.
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Among 18 genotypes analyzed, we were unable to record any significant differences in 5-methyl-2'-deoxycytidine levels, which suggested that age-related changes in global DNA methylation content are rather a function of time, and not a genetic component.
Developmental changes in expression of DNMT3B are indicative of a possible role in changes in methylation in cattle.
The expression levels of DNMT3a (zeige DNMT3A ELISA Kits) and DNMT3b were associated with several beef quality traits.
The following meta-analysis involved only Chinese population and further confirmed the significant association of -579G>T with gastric cancer but not lung cancer and suggested no significant association between -149C>T and risk of lung or gastric cancer. Collectively, DNMT3B -579G>T polymorphism is associated with gastric cancer risk in Chinese population
Among 9 candidate genes, GNB4 was identified and validated by qRT-PCR as a potential target silenced by DNA methylation via DNA methyltransferase 3B (DNMT3B).
Study suggests a role for DNMT3B in leukemogenesis in inv(16) acute myeloid leukemia, through MN1 methylation regulation.
Data indicate a role for DNA methyltransferase 3B (DNMT3B) suggesting that it might substitute for the absent accessory protein DNMT3L (zeige TRDMT1 ELISA Kits) to recruit DNMT3A (zeige DNMT3A ELISA Kits) in somatic cells.
These results provided evidence that the DNMT3B -283T>C polymorphism might significantly contribute to the lung cancer risk in the Asian population, but not the gastric cancer risk in the Chinese population.
There was no significant difference in the distribution of DNMT3B -579 G>T genotypes between the cases and controls.
The epigenetic targets AURKB (zeige AURKB ELISA Kits), AURKC and DNMT3B, and the global DNA methylation profile are regulated during HIV-1 replication in CD4 (zeige CD4 ELISA Kits)+ T cells, and this regulation can be influenced by the activation state of the cell at the time of infection.
Data suggest that female patients carrying the rs2424932 or rs998382 variants of DNA methyltransferase 3b (DNMT3) were more likely to develop Parkinson's disease (PD) than female controls.
Our study expands the mutation spectrum in ICF syndrome and supports that DNMT3B and ZBTB24 are the most common disease genes
Alternative splice variant of DNMT3B is associated with leukemia.
The epiblast expressed epithelial markers, MUC1 (zeige MUC1 ELISA Kits) and E-CADHERIN (zeige CDH1 ELISA Kits), and the pluripotency markers, DNMT3B and CRIPTO (zeige TDGF1 ELISA Kits).
The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1 (zeige DNMT1 ELISA Kits), DNMT3A (zeige DNMT3A ELISA Kits), and DNMT3B proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.
Altogether, the authors demonstrate that Dnmt3a (zeige DNMT3A ELISA Kits) and Dnmt3b protect the epidermis from tumorigenesis and that squamous carcinomas are sensitive to inhibition of PPAR-gamma (zeige PPARG ELISA Kits).
a new paradigm of transcriptional regulation critical for cardiac development and maturation that is controlled by the interaction of REST, DNMT3B and non-CpG methylation.
Together, this study described the regulation of Chk2 (zeige CHEK2 ELISA Kits) expression through promoter methylation by Dnmt3b and also presented a novel role of Chk2 (zeige CHEK2 ELISA Kits) during neuronal differentiation, which is independent of its previously known function in DNA damage response.
in mouse embryonic stem cells, Dnmt3b-dependent intragenic DNA methylation protects the gene body from spurious RNA polymerase II entry and cryptic transcription initiation
three DNA methyltransferases, Dnmt1, Dnmt3a, and Dnmt3b, have been identified. Dnmt3a and Dnmt3b are responsible for establishing DNA methylation patterns produced through their de novo-type DNA methylation activity in implantation stage embryos and during germ cell differentiation. Dnmt3-like (Dnmt3l), which is a member of the Dnmt3 family but does not possess DNA methylation
While lens epithelial cell survival requires DNMT1 (zeige DNMT1 ELISA Kits), morphologically normal lenses develop in the absence of both DNMT3A (zeige DNMT3A ELISA Kits) and DNMT3B.
Mechanical stimulation regulates osteoblastic genes expression via direct regulation of Dnmt3b.
a miR (zeige MLXIP ELISA Kits)-125b-DNMT3b-p53 (zeige TP53 ELISA Kits) signal pathway may exist in the vascular smooth muscle cells proliferation induced by homocysteine.
miR-29a mimic transfection lowered collagen 1alpha1, DNMT1, DNMT3b and SET1A expression in hepatic stellate cells.
dnmt7 specifically methylates no tail gene in the genome
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase which is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes primarily to the nucleus and its expression is developmentally regulated. Mutations in this gene cause the immunodeficiency-centromeric instability-facial anomalies (ICF) syndrome. Eight alternatively spliced transcript variants have been described. The full length sequences of variants 4 and 5 have not been determined.
DNA cytosine-5 methyltransferase 3 beta
, DNA (cytosine-5)-methyltransferase 3B
, DNA methyltransferase HsaIIIB
, DNA (cytosine-5-)-methyltransferase 3 beta
, DNA MTase HsaIIIB
, DNA methyltransferase 3B
, DNA (cytosine-5)-methyltransferase 3B-like
, DNA MTase MmuIIIB
, DNA methyltransferase MmuIIIB
, DNA (cytosine-5-)-methyltransferase 3 beta, like
, DNA (cytosine-5-)-methyltransferase 7
, LOW QUALITY PROTEIN: DNA (cytosine-5)-methyltransferase 3B