anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antikörper

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Zusätzlich bieten wir Ihnen DNA (Cytosine-5)-Methyltransferase 1 Kits (31) und DNA (Cytosine-5)-Methyltransferase 1 Proteine (10) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
DNMT1 1786 P26358
DNMT1 84350  
DNMT1 13433 P13864
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Top anti-DNA (Cytosine-5)-Methyltransferase 1 Antikörper auf

Showing 10 out of 537 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Maus Unkonjugiert ChIP, CyTOF, FACS, ICC, IF, IHC, IHC (ff), IHC (fro), IHC (p), IP, SimWes, WB Western Blot: Dnmt1 Antibody (60B1220.1) [ABIN252481] - Western blot analysis for Dnmt1 using ABIN252481 at 2 ug/ml against 10 µg of cell lysates of mouse ES cell. Immunohistochemistry: Dnmt1 Antibody (60B1220.1) [ABIN252481] - IHC analysis of Dnmt1 using ABIN252481 at 2 ug/ml on formalin-fixed, paraffin-embedded medullar kidney tissue sections 0.1 mg Anmelden zum Anzeigen 7 bis 9 Tage
Human Maus Unkonjugiert ChIP, IP, IHC, WB DNMT1 antibody (mAb) tested by Western blot. Detection of DNMT1 by Western blot. The analysis was performed using mouse ES whole-cell extract and DNMT1 antibody (mAb) at a 2 µg/ml dilution. 100 μg Anmelden zum Anzeigen 1 bis 2 Tage
Maus Kaninchen Unkonjugiert WB Researcher: AnonymousApplication: Western BlottingSpecies+tissue/cell type: Lane 1:241 µg mouse mesenchymal stem cell lysate Primary Antibody dilution: 1:0000<br />Secondary Antibody: Anti-rabbit-HRP <br />Secondary Antibody Dilution: 1:00,000 WB Suggested Anti-Dnmt1 Antibody Titration:  0.2-1 ug/ml  ELISA Titer:  1:62500  Positive Control:  Mouse Lung 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of DNMT1 Antibody (S1105) (ABIN387879) in MDA-MB435 cell line lysates (35 µg/lane). DNMT1 (arrow) was detected using the purified polyclonal antibody. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert FACS, WB The anti-Dnmt1 C-term Pab (ABIN387878) is used in Western blot to detect Dnmt1 in Jurkat cell lysate. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Human Kaninchen Unkonjugiert DB Dot blot analysis of anti-Dnmt1 Phospho-specific Pab (ABIN389901) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
Fisch Maus Unkonjugiert ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Fisch Maus Unkonjugiert ChIP, IP, IHC, WB Dnmt1, 18ug H1299 lysate 1 in1000 Western Blotting. 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Maus Unkonjugiert ELISA, IHC, WB Black line: Control Antigen (100 ng);Purple line: Antigen(10ng);Blue line: Antigen (50 ng);Red line: Antigen (100 ng); Dilution: 1/10000 Figure 1: Western blot analysis using DNMT1 mAb against human DNMT1 recombinant protein. (Expected MW is 42.6 kDa) Dilution: 1/500 - 1/2000 100 μL Anmelden zum Anzeigen 8 bis 11 Tage
Human Maus Unkonjugiert ELISA, WB Black line: Control Antigen (100 ng);Purple line: Antigen (10ng); Blue line: Antigen (50 ng); Red line:Antigen (100 ng) Western blot analysis using DNMT1 mAb against human DNMT1 (AA: 1317-1616) recombinant protein. (Expected MW is 59.3 kDa) 0.1 mg Anmelden zum Anzeigen 8 bis 11 Tage

Am meisten referenzierte anti-DNA (Cytosine-5)-Methyltransferase 1 Antikörper

  1. Human Monoclonal DNMT1 Primary Antibody für ChIP, CyTOF - ABIN252481 : Dennis, Fan, Geiman, Yan, Muegge: Lsh, a member of the SNF2 family, is required for genome-wide methylation. in Genes & development 2001 (PubMed)
    Show all 106 Pubmed References

  2. Human Monoclonal DNMT1 Primary Antibody für ChIP, IP - ABIN2668504 : Schnekenburger, Talaska, Puga: Chromium cross-links histone deacetylase 1-DNA methyltransferase 1 complexes to chromatin, inhibiting histone-remodeling marks critical for transcriptional activation. in Molecular and cellular biology 2007 (PubMed)
    Show all 4 Pubmed References

  3. Human Polyclonal DNMT1 Primary Antibody für DB, ELISA - ABIN4369817 : Saito, Kanai, Nakagawa, Sakamoto, Saito, Ishii, Hirohashi: Increased protein expression of DNA methyltransferase (DNMT) 1 is significantly correlated with the malignant potential and poor prognosis of human hepatocellular carcinomas. in International journal of cancer. Journal international du cancer 2003 (PubMed)
    Show all 3 Pubmed References

  4. Human Polyclonal DNMT1 Primary Antibody für WB - ABIN387879 : Peterson, Bögler, Taylor: p53-mediated repression of DNA methyltransferase 1 expression by specific DNA binding. in Cancer research 2003 (PubMed)
    Show all 7 Pubmed References

  5. Human Polyclonal DNMT1 Primary Antibody für FACS, WB - ABIN387878 : Leu, Rahmatpanah, Shi, Wei, Liu, Yan, Huang: Double RNA interference of DNMT3b and DNMT1 enhances DNA demethylation and gene reactivation. in Cancer research 2003 (PubMed)
    Show all 7 Pubmed References

  6. Human Polyclonal DNMT1 Primary Antibody für IHC (p), IHC - ABIN314281 : Nanduri, Makarenko, Reddy, Yuan, Pawar, Wang, Khan, Zhang, Kinsman, Peng, Kumar, Fox, Godley, Semenza, Prabhakar: Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. in Proceedings of the National Academy of Sciences of the United States of America 2012 (PubMed)
    Show all 2 Pubmed References

  7. Human Polyclonal DNMT1 Primary Antibody für EIA - ABIN358462 : Liao, Siu, Chan, Wong, Ngan, Chan, Li, Khoo, Cheung: Hypermethylation of RAS effector related genes and DNA methyltransferase 1 expression in endometrial carcinogenesis. in International journal of cancer. Journal international du cancer 2008 (PubMed)
    Show all 2 Pubmed References

  8. Human Polyclonal DNMT1 Primary Antibody für EIA - ABIN358447 : Yang, Andrade, Labialle, Moussette, Geneau, Sinnett, Belisle, Greenwood, Naumova: Parental effect of DNA (Cytosine-5) methyltransferase 1 on grandparental-origin-dependent transmission ratio distortion in mouse crosses and human families. in Genetics 2008 (PubMed)
    Show all 2 Pubmed References

  9. Human Polyclonal DNMT1 Primary Antibody für IF (p), IHC (p) - ABIN671796 : Khan, Tania, Wei, Mei, Fu, Cheng, Xu, Fu: Thymoquinone inhibits cancer metastasis by downregulating TWIST1 expression to reduce epithelial to mesenchymal transition. in Oncotarget 2015 (PubMed)

  10. Human Polyclonal DNMT1 Primary Antibody für IF (p), IHC (p) - ABIN757717 : Tan, Xu, Zeisberg, Zeisberg: High inorganic phosphate causes DNMT1 phosphorylation and subsequent fibrotic fibroblast activation. in Biochemical and biophysical research communications 2016 (PubMed)

Weitere Antikörper gegen DNA (Cytosine-5)-Methyltransferase 1 Interaktionspartner

Zebrafish DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. Dnmt1 stability requires UHRF1 (zeige UHRF1 Antikörper) phosphorylation and that crosstalk between the proteins is essential for the function of these two important epigenetic regulators during gastrulation

  2. Lsh (zeige HELLS Antikörper) Is Essential for Maintaining Global DNA Methylation (zeige HELLS Antikörper) Levels in Amphibia and Fish and Interacts Directly with Dnmt1.

  3. Dnmt1 is required for hematopoietic stem and progenitor cells maintenance via cebpa (zeige CEBPA Antikörper) regulation during definitive hematopoiesis in zebrafish

  4. These data provide the first evidence that Uhrf1 (zeige UHRF1 Antikörper) and Dnmt1 function is required for vertebrate lens development and maintenance.

  5. These results suggest that Dnmt1 activity helps direct histone methylation by Suv39h1 (zeige SUV39H1 Antikörper) and that, together, Dnmt1 and Suv39h1 (zeige SUV39H1 Antikörper) help guide the terminal differentiation of particular tissues.

  6. Data show that in dnmt1 homozygous mutants, reactivation of gfp expression occurs in a reproducible subset of cells, raising the possibility of different sensitivities or alternative silencing mechanisms in discrete cell populations.

  7. Thus, our data suggest that Dnmt1 is dispensable for pancreatic duct or endocrine cell formation, but not for acinar cell survival. In addition, Dnmt1 may influence the differentiation of pancreatic beta cell progenitors.

Human DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. the expression of WIF-1 (zeige WIF1 Antikörper) was low in GBC cells due to aberrant hypermethylation of its promoter region. Additionally, an alternative pathogenesis of GBC was indicated in which c-Jun (zeige JUN Antikörper) causes hypermethylation of the WIF-1 (zeige WIF1 Antikörper) promoter region, and represses the expression of WIF-1 (zeige WIF1 Antikörper) through transcriptional regulation and interaction with DNMT1 as an early event in the tumorigenesis of GBC.

  2. DNMT1 was downregulated in the Lung Cancer group and its expression was further reduced in the presence of increasing malignant burden as indicated by the endobronchial findings further suggesting an Lung Cancer-specific signature.

  3. SAC (zeige ADCY10 Antikörper) decreased the levels of 5-methylcytosine, DNMT activity, messenger RNA (mRNA) and protein levels of DNMT1. Additionally, SAC (zeige ADCY10 Antikörper) treatment resulted in re-expression of the mRNA and proteins of silenced tumor suppressor gene CDKN1A accompany with reduced cell division control 2 (zeige CDK1 Antikörper) expression.

  4. This work revealed the critical function of GOLM1 (zeige GOLM1 Antikörper)/miR (zeige MLXIP Antikörper)-200a/DNMT1 signaling pathway on regulating lung adenocarcinoma cell proliferation

  5. DNMT1 is associated with cell cycle and DNA replication gene sets in diffuse large B-cell lymphoma

  6. both messenger RNA and protein levels of KLF2 (zeige KLF2 Antikörper) in HUVEC co-treated with LPS (zeige IRF6 Antikörper) and DNA methyltransferase (DNMT) 1 small interfering RNA were dramatically higher than that treated with LPS (zeige IRF6 Antikörper) only.

  7. By perturbing BCL11A (zeige BCL11A Antikörper)-DNMT1 interaction, miR (zeige MLXIP Antikörper)-137 impairs cancer stemness and suppresses tumor development in Triple negative breast cancer.

  8. DNMT3B (zeige DNMT3B Antikörper) rs1569686 gene polymorphism in women might be a genetic marker for the susceptibility to recurrent spontaneous abortion

  9. we demonstrated that the downregulation of CLDN6 (zeige CLDN6 Antikörper) is regulated through promoter methylation by DNMT1, which depends on the SMAD2 (zeige SMAD2 Antikörper) pathway, and that CLDN6 (zeige CLDN6 Antikörper) is a key regulator in the SMAD2 (zeige SMAD2 Antikörper)/DNMT1/CLDN6 (zeige CLDN6 Antikörper) pathway to inhibit EMT (zeige ITK Antikörper), migration and invasion of breast cancer cells

  10. GNAO1 (zeige GNAO1 Antikörper) transcription was inhibited by promoter hypermethylation, contributing to its low expression. It was further revealed that the silencing effect was regulated by methyltransferase 1 (DNMT1), and was further enhanced by transforming growth factor beta (TGF-beta).

Pig (Porcine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. Dnmt1 was indispensable for oocyte cytoplasmic maturation, providing a novel role for Dnmt1 in the regulation of oocyte maturation.

  2. Data show that the expression levels of the 5 epigenetic modifying genes Dnmt1, Dnmt3a (zeige DNMT3A Antikörper), Hdac1 (zeige HDAC1 Antikörper), Kdm3a (zeige KDM3A Antikörper) and Uhrf1 (zeige UHRF1 Antikörper) were higher in group pig in highland (TH) than in group Yorkshire in highland (YH).

  3. DNMT1o is localized mainly in the nuclei of oocytes and early embryos, whereas DNMT1s is expressed in the ooplasm (zeige NLRP5 Antikörper) cortex of oocytes and cytoplasm of early embryos.

  4. results indicate that loss of Dnmt1 in the maternal nucleus during SCNT significantly contributes to the unfaithful maintenance of methylation imprints in cloned embryos

  5. Oocyte-specific Dnmt1 is cytoplasmic during early development.

  6. Dnmt1 mRNA abundance plays an important role during protein regulation, Dnmt1 enzyme is mainly posttranscriptionally regulated.

Cow (Bovine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. DNMT1 silencing significantly decreased the methylation levels of miR (zeige MYLIP Antikörper)-29b promoter, up-regulated miR (zeige MYLIP Antikörper)-29b expression and inhibited bovine viral diarrhea virus replication.

  2. Through down-regulating the expression of DNMT1, miR (zeige MYLIP Antikörper)-152 reduced Global DNA methylation (zeige HELLS Antikörper) and the activity of DNMT to reactivate the lactation signal transduction genes Akt (zeige AKT1 Antikörper) and Ppar gamma (zeige PPARG Antikörper).

  3. More DNMT1 mRNA was detected in the transgenic somatic cell nuclear transfer (SCNT) group than the other three groups. Hsp 70.1 mRNA was detected in the in vitro fertilzation embryos. Mash2 (zeige ASCL2 Antikörper) mRNA was present at highest levels in transgenic SCNT embryos.

  4. Our results indicate an essential role for Dnmt1 during bovine preimplantation development (zeige MTA2 Antikörper), and suggest proper transcriptional reprogramming of this gene family in SCNT embryos.

  5. Abnormal gene expression of DNMT, INFT, and MHC1 was noted in the majority of cloned embryos, indicating inefficient nuclear reprogramming and retarded embryo development.

  6. Results describe the alternative splicing and expression analysis of bovine DNA methyltransferase 1.

  7. Report inhibition of DNA methyltransferase 1 expression in bovine fibroblast cells used for nuclear transfer.

Arabidopsis thaliana DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. The findings reveal that MET1-mediated shoot regeneration is regulated by the cytokinin-induced cell cycle, and provide new insights into the regulation of DNA methylation (zeige HELLS Antikörper) in shoot regeneration.

  2. Long-term stability and epigenetic features differ for individual loci. Our data show that over-expression of MET1, and potentially of other genes encoding epigenetic factors, offers an alternative strategy to identify epigenetic target genes and to create novel epi (zeige TFPI Antikörper)-alleles

  3. MET1 confines ARID1 to the vegetative cell of male gametes, but ARID1 conversely represses MET1 in the central cell of female gametes.

  4. MET1 is a thylakoid-associated TPR protein involved in photosystem II supercomplex formation and repair in Arabidopsis

  5. Met1 gene expression throughout normal development, particularly in the flower

  6. MET1 is a contributor to epigenetic diversity in Arabidopsis.

  7. VIM (zeige VIM Antikörper) proteins regulate genome-wide epigenetic gene silencing through coordinated modulation of DNA methylation (zeige HELLS Antikörper) and histone modification status in collaboration with MET1

  8. VIM (zeige VIM Antikörper) proteins function in transcriptional regulation via their roles in the MET1 DNA methylation (zeige HELLS Antikörper) pathway.

  9. Genetic studies indicate that the Polycomb (zeige CBX2 Antikörper) Repressive Complex 2 (PRC2) but not the DNA METHYLTRANSFERASE1 (MET1) is involved in regulating imprinted expression in the embryo. [MET1]

  10. MET1 restores body methylation, which is region-specific but random with respect to the affected CG sites, and is moderately although not decisively influenced by transcription.

Mouse (Murine) DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Interaktionspartner

  1. Increased shear stress without a change in flow direction initiates arteriogenic growth; however, it also elicits DNMT1-dependent endothelial cells DNA hypermethylation. In turn, this diminishes mechanosensing, augments shear stress set point, and constrains the ultimate arteriogenic capacity of the vessel.

  2. Single-cell transcriptome analysis detected Dnmt1 expression in murine migratory GABAergic embryonic preoptic area (POA)-derived cells. Deletion of Dnmt1 in postmitotic immature cells of the POA caused defective migration and severely diminished adult cortical interneuron numbers. DNMT1 preserves the migratory shape in part through negative regulation of Pak6 (zeige PAK6 Antikörper), which stimulates neuritogenesis postmigration.

  3. The aim of the present study is to investigate spatial and temporal expression levels and subcellular localizations of the DNMT1, DNMT3A (zeige DNMT3A Antikörper), and DNMT3B (zeige DNMT3B Antikörper) proteins in the mouse germinal vesicle (GV) and metaphase II (MII) oocytes, and early embryos from 1-cell to blastocyst stages.

  4. DNMT1 ablation from kidney proximal tubules enhanced cisplatin-induced acute kidney injury in mice, suggesting a renoprotective role of DNA methylation (zeige HELLS Antikörper).

  5. Epigenetic enhancement of the post-replicative DNA mismatch repair of mammalian genomes by a Hemi-(m)CpG-Np95 (zeige UHRF1 Antikörper)-Dnmt1 axis has been demonstrated for humans and mice.

  6. We show that expression of Id-1 (zeige IDH1 Antikörper), a negative regulator of myogenesis, is enhanced in Dnmt1-deficient cultures, leading to enhanced transdifferentiation of myoblasts toward the osteogenic lineage. Thus, these studies demonstrate that Dnmt1 influences cellular identity and determines lineage fidelity.

  7. this study shows that DNMT1 might directly repress p53 (zeige TP53 Antikörper), at least in part, by binding to the p53 (zeige TP53 Antikörper) promoter locus

  8. Knockdown of DNMT3A (zeige DNMT3A Antikörper) or DNMT1 protected neurons against mutant Htt (zeige HTT Antikörper)-induced toxicity, together demonstrating a requirement for DNMTs in mutant Htt (zeige HTT Antikörper)-triggered neuronal death and suggesting a neurodegenerative mechanism based on DNA methylation (zeige HELLS Antikörper)-mediated transcriptional repression.

  9. Sp1 (zeige SP1 Antikörper)/NFkappaB p65 (zeige NFkBP65 Antikörper)-Dnmt1 pathway may be exploited as a therapeutic target for protecting against podocyte injury in diabetic nephropathy.

  10. 2-hydroxyglutarate bound to DNMT1 and stimulated its association with the RIP3 (zeige MPRIP Antikörper) promoter, inducing hypermethylation that reduces RIP3 (zeige MPRIP Antikörper) protein and consequently impaired RIP3 (zeige MPRIP Antikörper)-dependent necroptosis.

DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antigen-Profil

Protein Überblick

DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene.

Genbezeichner und Symbole assoziert mit DNMT1

  • DNA methyltransferase 1 (DNMT1) Antikörper
  • DNA (cytosine-5-)-methyltransferase 1 (dnmt1) Antikörper
  • DNA methyltransferase 1 (Dnmt1) Antikörper
  • methyltransferase 1 (MET1) Antikörper
  • DNA methyltransferase (cytosine-5) 1 (Dnmt1) Antikörper
  • ADCADN Antikörper
  • AIM Antikörper
  • cb983 Antikörper
  • cb1075 Antikörper
  • Cxxc9 Antikörper
  • DDM2 Antikörper
  • dmnt1 Antikörper
  • DMT01 Antikörper
  • DMT1 Antikörper
  • Dnmt Antikörper
  • Dnmt1o Antikörper
  • fb05h01 Antikörper
  • HSN1E Antikörper
  • m.MmuI Antikörper
  • MCMT Antikörper
  • Met-1 Antikörper
  • Met1 Antikörper
  • MET2 Antikörper
  • methyltransferase 1 Antikörper
  • METI Antikörper
  • MommeD2 Antikörper
  • mta Antikörper
  • MTase Antikörper
  • wu:fb05h01 Antikörper

Bezeichner auf Proteinebene für DNMT1

DNA (cytosine-5)-methyltransferase 1 , ddn , CXXC-type zinc finger protein 9 , DNA MTase HsaI , DNA methyltransferase HsaI , m.HsaI , DNA methyltransferase 1 , DNA (cytosine 5 ) methyltransferase 1 , DNA methyltransferase (cytosine 5 ) methyltransferase , DNA methyltransferase b , DNA MTase RnoIP , DNA methyltransferase (cytosine-5) 1 , DNA methyltransferase I , MCMT , m.RnoIP , DNA MTase GgaI , DNA MeTase , DNA methyltransferase GgaI , m.GgaI , DNA MTase MmuI , DNA methyltransferase MmuI

443549 Ovis aries
30430 Danio rerio
1786 Homo sapiens
476715 Canis lupus familiaris
606746 Sus scrofa
281119 Bos taurus
84350 Rattus norvegicus
396011 Gallus gallus
834975 Arabidopsis thaliana
13433 Mus musculus
Ausgewählte Anbieter für anti-DNA (Cytosine-5)-Methyltransferase 1 (DNMT1) Antikörper
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