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The protein encoded by DIXDC1 is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. Zusätzlich bieten wir Ihnen DIX Domain Containing 1 Proteine (7) und DIX Domain Containing 1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an.
Showing 10 out of 48 products:
Human Polyclonal DIXDC1 Primary Antibody für ELISA, WB - ABIN4288484
Wu, Jing, Ma, Wu, Ding, Fan, Fan: DIXDC1 co-localizes and interacts with gamma-tubulin in HEK293 cells. in Cell biology international 2009
DIXDC1 might participate in the development of glioma.
Overexpression of DIXDC1 correlates with enhanced cell growth and poor prognosis in human pancreatic ductal adenocarcinoma.
found that DIXDC1 could promote cell proliferation via modulating cell cycle progression and PI3K (zeige PIK3CA Antikörper)/AKT (zeige AKT1 Antikörper) signaling pathway in NHLs
Taken together, our results suggest that DIXDC1 plays an important role in regulating prostate cancer cell proliferation and invasion. Targeting DIXDC1 by miR (zeige MLXIP Antikörper)-1271 may be a promising therapeutic strategy for prostate cancer.
Downregulated expression of DIXDC1 is associated with hepatocellular carcinoma.
DIXDC1 was overexpressed in gastric cancer and correlated with poor prognosis.
DIXDC1 is associated with stage and prognosis in non-small cell lung cancer, and may promote invasion and migration through PI3K (zeige PIK3CA Antikörper)-AKT (zeige AKT1 Antikörper)/AP-1 (zeige FOSB Antikörper)-dependent activation of metalloproteinases
DIXDC1 depletion results in upregulation of Snail1 (zeige SNAI1 Antikörper) in a FAK (zeige PTK2 Antikörper)-dependent manner, leading to increased cell invasion. MARK1 (zeige MARK1 Antikörper) phosphorylation of DIXDC1 is required for its localization to focal adhesions and ability to suppress metastasis in mice.
Transgenic DIXDC1 might contribute to pathophysiology underlying abnormal behaviors in sch (zeige DISC1 Antikörper)izophrenia and other major psychiatric disorders in mice.
a molecular mechanism for Ccd1 (zeige RUNX2 Antikörper)-mediated Wnt (zeige WNT2 Antikörper) activation in that Ccd1 (zeige RUNX2 Antikörper) converts latent polymeric Dvl (zeige DVL2 Antikörper) to a biologically active oligomer(s).
DIXDC1 is a regulator of cortical dendrite and synaptic development.
Abnormal behavior in Dixdc1 mice could elucidate molecular pathophysiology involving Disc1 (zeige DISC1 Antikörper) in major mental illnesses.
crystals of the Ccd1 DIX domain belonged to space group P2(1)2(1)2(1), with unit-cell parameters a=72.9, b=75.7, c=125.6 A. An X-ray diffraction data set was collected at 3.0 A resolution
a molecular mechanism for Ccd1-mediated Wnt (zeige WNT2 Antikörper) activation in that Ccd1 converts latent polymeric Dvl (zeige DVL1 Antikörper) to a biologically active oligomer(s).
DIXDC1 encodes a novel protein with a myosine-tail homologous domain and C-terminal DIX domain
mouse Ccd1 functions as a positive regulator of the Wnt (zeige WNT2 Antikörper)/beta-catenin (zeige CTNNB1 Antikörper) pathway. Furthermore, Ccd1 is highly expressed and co-localized with Wnt (zeige WNT2 Antikörper) signaling molecules in the embryonic and adult brain.
These results indicate that Ccd1 is a novel positive regulator in this Wnt (zeige WNT2 Antikörper) signaling pathway during zebrafish neural patterning.
The protein encoded by this gene is a positive regulator of the Wnt signaling pathway and interacts with AXIN1, DVL2, and MAP3K1. The encoded protein is found associated with gamma tubulin at the centrosome. Three transcript variants, two protein-coding and the other non-protein coding, have been found for this gene. The longer isoform also associates with actin stress fibers while the shorter isoform does not.
DIX domain containing 1
, coiled-coil protein DIX1
, DIX domain-containing protein 1
, DIX domain-containing protein 1-A
, coiled-coil DIX 1
, coiled-coil protein DIX1-A