anti-DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) Antikörper

DIRAS3 is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Human DIRAS3 DIRAS3 9077 O95661
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Showing 10 out of 43 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert FACS, IHC (p), WB DIRAS3 Antibody (ABIN652072) western blot analysis in WiDr cell line lysates (35 µg/lane). This demonstrates the DIRAS3 antibody detected the DIRAS3 protein (arrow). DIRAS3 Antibody (ABIN652072) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Anmelden zum Anzeigen 10 bis 11 Tage
$324.50
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Human Maus Unkonjugiert IP, ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage
$581.17
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Human Kaninchen Unkonjugiert IHC, WB Western blot analysis of extracts of various cells, using DIRAS3 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
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Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat brain labeled with Anti-ARHI Polyclonal Antibody, Unconjugated (ABIN681448) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
$306.90
Details
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Immunohistochemistry-Paraffin: DIRAS3 Antibody [NBP1-90105] - Immunohistochemical staining of human cerebellum shows strong nuclear positivity in purkinje cells. Western Blot: DIRAS3 Antibody [NBP1-90105] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY401484) 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
$491.63
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Human Kaninchen Unkonjugiert ELISA, WB   0.1 mg Anmelden zum Anzeigen 2 bis 3 Tage
$350.00
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Human Maus Unkonjugiert ELISA, WB Western Blot analysis of DIRAS3 expression in transfected 293T cell line by DIRAS3 monoclonal antibody (M01A), clone 1G4.<br><br>Lane 1: DIRAS3 transfected lysate (Predicted MW: 25.9 KDa).<br>Lane 2: Non-transfected lysate.<br> Western Blot detection against Immunogen (36.74 KDa) . 200 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
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Human Maus Unkonjugiert ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$305.71
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Human Kaninchen Unkonjugiert WB Western blot analysis of DIRAS3 expression in NIH3T3 (A), mouse liver (B), mouse brain (C), rat liver (D), rat kidney (E) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
$487.50
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Human Kaninchen Unkonjugiert ELISA, IHC, IHC (p), WB   50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$484.00
Details

Am meisten referenzierte anti-DIRAS3 Antikörper

  1. Human Polyclonal DIRAS3 Primary Antibody für ELISA, WB - ABIN563932 : Li, Ramani, Sun, Zee, Grant, Yang, Xia, Oh, Ko, Mato, Lu: Forced expression of methionine adenosyltransferase 1A in human hepatoma cells suppresses in vivo tumorigenicity in mice. in The American journal of pathology 2010 (PubMed)

Weitere Antikörper gegen DIRAS3 Interaktionspartner

Pig (Porcine) DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) Interaktionspartner

  1. polymorphism-based approach was used to detect the imprinting status of NNAT (zeige NNAT Antikörper) and DIRAS3 genes in five heterozygous pigs (based on SNP) of Large White and Meishan F(1) hybrids

Human DIRAS Family, GTP-Binding RAS-Like 3 (DIRAS3) Interaktionspartner

  1. lncRNA GAS5 functions as a competing endogenous RNA for miR (zeige MLXIP Antikörper)-221 to suppress cell growth and EMT (zeige ITK Antikörper) in osteosarcoma by regulating the miR (zeige MLXIP Antikörper)-221/ARHI pathway.

  2. DiRas3 binds to KSR1 (zeige KSR1 Antikörper) independently of its interaction with activated Ras and RAF (zeige RAF1 Antikörper).

  3. We demonstrate that DIRAS3 knock-down (KD) in adipose stromal/progenitor cells (ASCs) induces activation of Akt (zeige AKT1 Antikörper)-mTOR (zeige FRAP1 Antikörper) signaling and proliferation arrest. DIRAS3 KD ASCs lose the potential to form colonies and are negative for Ki-67 (zeige MKI67 Antikörper). Moreover, silencing of DIRAS3 results in a premature senescence phenotype.

  4. ARHI-mediated up-regulation of glycolysis and glutaminolysis was found to be autophagy-dependent and inhibition of these metabolic pathways resulted in decreased cell viability.

  5. The overexpression of ARHI promotes colon cancer SW480 cell apoptosis by inhibiting the level of Akt (zeige AKT1 Antikörper).

  6. Transcriptional, but not post-transcriptional, silencing of GNG12-AS1 (zeige PTGDR Antikörper) causes concomitant upregulation of DIRAS3, indicating a function in transcriptional interference.

  7. ARHI mRNA and protein expression is markedly decreased in osteosarcoma MG-63 cells lines. Overexpression of ARHI inhibits cell viability and proliferation.

  8. ARHI-mediated autophagy-associated cell death enhances chemosensitivity to cisplatin in ovarian cancer cell lines and xenografts.

  9. EZH2 (zeige EZH2 Antikörper)-''induced H3K27me3 is associated with epigenetic repression of the ARHI tumor-suppressor gene in epithelial ovarian cancer

  10. ARHI competes with RanGTPase and interacts with importin beta (zeige KPNB1 Antikörper) via basic-acidic patch interaction, which leads to inhibition of STAT3 (zeige STAT3 Antikörper) translocation.

DIRAS3 Antigen-Profil

Protein Überblick

This gene is a member of the ras superfamily, and is expressed in normal ovarian and breast epithelial cells, but not in ovarian and breast cancers. It is an imprinted gene, with monoallelic expression of the paternal allele, which is associated with growth suppression. Thus, this gene appears to be a putative tumor suppressor gene whose function is abrogated in ovarian and breast cancers.

Genbezeichner und Symbole assoziert mit DIRAS3

  • DIRAS family GTPase 3 (DIRAS3) Antikörper
  • DIRAS family GTP binding RAS like 3 (diras3) Antikörper
  • ARHI Antikörper
  • DIRAS3 Antikörper
  • NOEY2 Antikörper

Bezeichner auf Proteinebene für DIRAS3

DIRAS family, GTP-binding RAS-like 3 , GTP-binding protein Di-Ras3 , GTP-binding RAS-like protein 3 , distinct subgroup of the Ras family member 3 , ras homolog gene family, member I , rho-related GTP-binding protein RhoI

GENE ID SPEZIES
456930 Pan troglodytes
504559 Bos taurus
701273 Macaca mulatta
733668 Sus scrofa
100135197 Xenopus (Silurana) tropicalis
100147791 Ovis aries
9077 Homo sapiens
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