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CYGB encodes a globin protein found in vertebrate cells. Zusätzlich bieten wir Ihnen Cytoglobin Antikörper (59) und Cytoglobin Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.
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Human CYGB ELISA Kit für Sandwich ELISA - ABIN418125
Vij, Hardej: Alterations in antioxidant/oxidant gene expression and proteins following treatment of transformed and normal colon cells with tellurium compounds. in Environmental toxicology and pharmacology 2016
The results uncover unexpected properties of zebrafish cytoglobin 1 and reveal the pivotal role of cytoglobin 1 in the transition of heme cytoglobin 1 from six-coordinate to five-coordinate oxygen carriers and nitrite reductases.
Thus, the absence of Cygb in pericytes provokes organ abnormalities, possibly via derangement of the nitric oxide and antioxidant defence system and through accelerated cellular senescence.
Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF (zeige REST ELISA Kits) being an upstream regulator.
Cygb, expressed in hepatic stellate cells during liver fibrosis, plays role in cancer development with nonalcoholic steatohepatitis.
Studied hepatic stellate cell cytoglobin involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1 (zeige CYP2E1 ELISA Kits).
cytoglobin serves an important role in muscle repair and regeneration
Cygb deficiency induces susceptibility to cancer development in the liver and lungs of mice exposed to N,N-diethylnitrosamine
The anatomical data indicate a role in NO signalling for cytoglobin and involvement in sleep-wake cycling for cytoglobin and neuroglobin (zeige NGB ELISA Kits)
The nuclear localization of cytoglobin opens new perspectives for possible function(s) of globin-folded proteins as transcriptional regulators.
differential expression of cytoglobin argues against a general respiratory function of this molecule, but rather indicates a connective tissue-specific function
cytoglobin is significantly upregulated upon hypoxia and this is dependent on the tissue and severity of hypoxia
the study reveals a novel mechanism for the regulated expression of Cygb and also assigns a new role to Cygb in cell cycle control.
Data suggest that cytochrome b5 (CYB5 (zeige CYB5A ELISA Kits)) and cytochrome b5 reductase 3 (CYB5R3 (zeige CYB5R3 ELISA Kits)) can reduce human cytoglobin (CYGB) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin (zeige HBB ELISA Kits) and myoglobin (zeige MB ELISA Kits); the three proteins (CYB5 (zeige CYB5A ELISA Kits)+CYB5R3 (zeige CYB5R3 ELISA Kits)+CYGB) appear to constitute a metabolon involved in generation of nitric oxide.
DeltaNp63-CYGB axis is also present in lung and breast cancer cell lines, indicating that CYGB-mediated ROS (zeige ROS1 ELISA Kits)-scavenging activity may also have a role in epithelial tumours
Propose a bipartite lipid binding model that rationalizes the modes of interactions of cytoglobin with phospholipids, the effects on structural re-arrangements and the peroxidase activity of the hemoprotein.
This review provides an overview of the proposed role of cytoglobin and explores its potential functional role as a biomarker for cancer and other diseases
Cygb stabilizes p53 (zeige TP53 ELISA Kits) by inhibiting its ubiquitination and elicit cell cycle arrest in DNA damaged cells.
The cysteine redox state of the monomer controls histidine dissociation rate constants and hence extrinsic ligand binding in human cytoglobin.
The monomeric cytoglobin protein with an internal disulfide bond between the two cysteine residues Cys38 and Cys83, interacts with lipids to induce a change in haem co-ordination.
Protein multimerization may be a mechanism that triggers physiological functions of human cytoglobin.
This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.
, stellate cell activation associated protein
, stellate cell activation-associated protein