anti-Cytoglobin (CYGB) Antikörper

CYGB encodes a globin protein found in vertebrate cells. Zusätzlich bieten wir Ihnen Cytoglobin Kits (19) und Cytoglobin Proteine (15) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
CYGB 114886 Q9CX80
CYGB 114757 Q8WWM9
CYGB 170520 Q921A4
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Top anti-Cytoglobin Antikörper auf

Showing 10 out of 73 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Human Kaninchen Unkonjugiert IHC (p), WB Western blot analysis of Cytoglobin using anti-Cytoglobin antibody .  Electrophoresis was performed on a 5-20% SDS-PAGE gel at 70V (Stacking gel) / 90V (Resolving gel) for 2-3 hours. The sample well of each  Lane was loaded with 50ug of sample under reducing conditions.   Lane 1: rat small intestine tissue lysates,   Lane 2: mouse small intestine tissue lysates,  After Electrophoresis, proteins were transferred to a Nitrocellulose membrane at 150mA for 50-90 minutes. Blocked the membrane with 5% Non-fat Milk/ TBS for 1.5 hour at RT. The membrane was incubated with rabbit anti-Cytoglobin antigen affinity purified polyclonal antibody (Catalog # ) at 0.5 µg/mL overnight at 4°C, then washed with TBS-0.1%Tween 3 times with 5 minutes each and probed with a goat anti-rabbit IgG-HRP secondary antibody at a dilution of 1:10000 for 1.5 hour at RT. The signal is developed using an Enhanced Chemiluminescent detection (ECL) kit (Catalog # EK1002) with Tanon 5200 system. A specific band was detected for Cytoglobin at approximately 21KD. The expected band size for Cytoglobin is at 21KD. IHC analysis of Cytoglobin using anti- Cytoglobin antibody . Cytoglobin was detected in paraffin-embedded section of mouse intestine tissues. Heat mediated antigen retrieval was performed in citrate buffer (pH6, epitope retrieval solution) for 20 mins. The tissue section was blocked with 10% goat serum. The tissue section was then incubated with 1µg/ml rabbit anti- Cytoglobin Antibody  overnight at 4°C. Biotinylated goat anti-rabbit IgG was used as secondary antibody and incubated for 30 minutes at 37°C. The tissue section was developed using Strepavidin-Biotin-Complex (SABC)(Catalog # SA1022) with DAB as the chromogen. 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
Human Maus Unkonjugiert ELISA, IF, IHC, WB Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (46.64 KDa) . Dilution: 1:500~1000 100 μg Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert ICC, IF, IHC (p), WB Western Blot: Cytoglobin Antibody [NBP2-16084] - Sample (30 ug of whole cell lysate) A: IMR32 12% SDS PAGE gel, diluted at 1:2000. Immunocytochemistry/Immunofluorescence: Cytoglobin Antibody [NBP2-16084] - Immunofluorescence analysis of methanol-fixed A431, using antibody at 1:500 dilution. 0.1 mL Anmelden zum Anzeigen 8 bis 11 Tage
Human Kaninchen Unkonjugiert WB Western blot analysis of Cytoglobin expression in HeLa (A), Raw264.7 (B), PC12 (C) whole cell lysates. 200 μL Anmelden zum Anzeigen 13 bis 14 Tage
Human Kaninchen Unkonjugiert EIA, WB Western blot analysis of Cytoglobin (N-term) in HepG2 cell line lysates (35ug/lane). This demonstrates the CYGB antibody detected the CYGB protein (arrow). 0.4 mL Anmelden zum Anzeigen 6 bis 8 Tage
Human Kaninchen Unkonjugiert IHC, IHC (p), WB Western Blot: Cytoglobin Antibody [NBP1-89701] - Lane 1: Marker [kDa] 250, 130, 95, 72, 55, 36, 28, 17, 10.Lane 2: Negative control (vector only transfected HEK293T lysate).Lane 3: Over-expression lysate (Co-expressed with a C-terminal myc-DDK tag (~3.1 kDa) in mammalian HEK293T cells, LY408741) Immunohistochemistry-Paraffin: Cytoglobin Antibody [NBP1-89701] - Staining of human duodenum shows moderate slightly granular cytoplasmic positivity in glandular cells. 0.1 mL Anmelden zum Anzeigen 10 bis 13 Tage
Human Kaninchen Unkonjugiert IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat colon tissue labeled with Anti-Cygb Polyclonal Antibody (ABIN670566), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining Formalin-fixed and paraffin embedded rat brain tissue labeled with Anti-Cygb Polyclonal Antibody (ABIN670566), Unconjugated at 1:200, followed by conjugation to the secondary antibody and DAB staining 100 μL Anmelden zum Anzeigen 3 bis 7 Tage
Human Maus Unkonjugiert IF, IHC (p), ELISA, WB Western Blot analysis of CYGB expression in transfected 293T cell line by CYGB monoclonal antibody (M02), clone 1A1.<br><br>Lane 1: CYGB transfected lysate(21 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunoperoxidase of monoclonal antibody to CYGB on formalin-fixed paraffin-embedded human heart. [antibody concentration 3 ug/ml] 100 μg Anmelden zum Anzeigen 11 bis 12 Tage
Ratte Kaninchen Unkonjugiert ICC, IHC, WB Figure. Western Blot; Lane1: Rat Serum; Lane2: Rat Heart Tissue; Lane3: Rat Kidney Tissue. Figure. Western Blot; Sample: Recombinant CYGB, Rat. 100 μg Anmelden zum Anzeigen 13 bis 16 Tage
Human Maus Unkonjugiert IF, ELISA, WB 100 μg Anmelden zum Anzeigen 7 bis 9 Tage

Am meisten referenzierte anti-Cytoglobin Antikörper

  1. Human Monoclonal CYGB Primary Antibody für IF, IHC (p) - ABIN566715 : Li, Lee, Pouranfar, Brittian, Clair, Row, Wang, Gozal: Hypoxia differentially regulates the expression of neuroglobin and cytoglobin in rat brain. in Brain research 2006 (PubMed)
    Show all 5 Pubmed References

  2. Human Polyclonal CYGB Primary Antibody für IF (p), IHC (p) - ABIN670566 : Xu, Huang, Xie, Lin, Guo, Zhuang, Lin, Zhou, Li, Huang, Wei, Man, Zhang: The expression of cytoglobin as a prognostic factor in gliomas: a retrospective analysis of 88 patients. in BMC cancer 2013 (PubMed)

  3. Human Polyclonal CYGB Primary Antibody für ICC, IF - ABIN4302128 : Svenson, Case, Cole, Hwang, Kabir, Lazarus, Lim Soo, Ng, Peters, Shum, Sweryda-Krawiec, Tripathi, van der Poll, Eliasof: Tumor Selective Silencing Using an RNAi-Conjugated Polymeric Nanopharmaceutical. in Molecular pharmaceutics 2016 (PubMed)

  4. Human Monoclonal CYGB Primary Antibody für ELISA, IF - ABIN394736 : Mogal, Watson, Ozsolak, Salavaggione, Humphrey: Gene expression profiles and differential cytoglobin expression in atrophy and adenocarcinoma of the prostate. in The Prostate 2012 (PubMed)

Weitere Antikörper gegen Cytoglobin Interaktionspartner

Zebrafish Cytoglobin (CYGB) Interaktionspartner

  1. The results uncover unexpected properties of zebrafish cytoglobin 1 and reveal the pivotal role of cytoglobin 1 in the transition of heme cytoglobin 1 from six-coordinate to five-coordinate oxygen carriers and nitrite reductases.

Mouse (Murine) Cytoglobin (CYGB) Interaktionspartner

  1. we identified CYGB as an important regulator of osteosarcoma (OS) extravasation and highlighted the importance of the LEF1 (zeige LEF1 Antikörper)-CYGB regulatory axis in OS metastasis to the lungs.

  2. This study demonstrated the role of CYGB in fibroblast cell motility and proliferation. CYGB could be a promising candidate for further studies as a potential target for diseases related to cell migration such as cancer and chronic wound treatment.

  3. Thus, the absence of Cygb in pericytes provokes organ abnormalities, possibly via derangement of the nitric oxide and antioxidant defence system and through accelerated cellular senescence.

  4. Findings provide evidence for the loss of globin-linked neuroprotection to be linked to Alzheimer's disease angiopathogenesis, while raising the possibility of REST/ NRSF (zeige REST Antikörper) being an upstream regulator.

  5. Cygb, expressed in hepatic stellate cells during liver fibrosis, plays role in cancer development with nonalcoholic steatohepatitis.

  6. Studied hepatic stellate cell cytoglobin involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1 (zeige CYP2E1 Antikörper).

  7. cytoglobin serves an important role in muscle repair and regeneration

  8. Cygb deficiency induces susceptibility to cancer development in the liver and lungs of mice exposed to N,N-diethylnitrosamine

  9. The anatomical data indicate a role in NO signalling for cytoglobin and involvement in sleep-wake cycling for cytoglobin and neuroglobin (zeige NGB Antikörper)

  10. The nuclear localization of cytoglobin opens new perspectives for possible function(s) of globin-folded proteins as transcriptional regulators.

Human Cytoglobin (CYGB) Interaktionspartner

  1. the study reveals a novel mechanism for the regulated expression of Cygb and also assigns a new role to Cygb in cell cycle control.

  2. Data suggest that cytochrome b5 (CYB5 (zeige CYB5A Antikörper)) and cytochrome b5 reductase 3 (CYB5R3 (zeige CYB5R3 Antikörper)) can reduce human cytoglobin (CYGB) and zebrafish cytoglobins at rates up to 250-fold higher than those reported for the known physiological substrates, hemoglobin (zeige HBB Antikörper) and myoglobin (zeige MB Antikörper); the three proteins (CYB5 (zeige CYB5A Antikörper)+CYB5R3 (zeige CYB5R3 Antikörper)+CYGB) appear to constitute a metabolon involved in generation of nitric oxide.

  3. DeltaNp63-CYGB axis is also present in lung and breast cancer cell lines, indicating that CYGB-mediated ROS (zeige ROS1 Antikörper)-scavenging activity may also have a role in epithelial tumours

  4. Propose a bipartite lipid binding model that rationalizes the modes of interactions of cytoglobin with phospholipids, the effects on structural re-arrangements and the peroxidase activity of the hemoprotein.

  5. This review provides an overview of the proposed role of cytoglobin and explores its potential functional role as a biomarker for cancer and other diseases

  6. Cygb, expressed in hepatic stellate cells during liver fibrosis, plays role in cancer development with nonalcoholic steatohepatitis.

  7. Cygb stabilizes p53 (zeige TP53 Antikörper) by inhibiting its ubiquitination and elicit cell cycle arrest in DNA damaged cells.

  8. The cysteine redox state of the monomer controls histidine dissociation rate constants and hence extrinsic ligand binding in human cytoglobin.

  9. The monomeric cytoglobin protein with an internal disulfide bond between the two cysteine residues Cys38 and Cys83, interacts with lipids to induce a change in haem co-ordination.

  10. Protein multimerization may be a mechanism that triggers physiological functions of human cytoglobin.

Cytoglobin (CYGB) Antigen-Profil

Protein Überblick

This gene encodes a globin protein found in vertebrate cells. The encoded protein is described as a hexacoordinate hemoglobin which binds ligand differently from the pentacoordinate hemoglobins involved in oxygen transport, and may be involved in protection during oxidative stress. This gene is located on chromosome 17 in the same region as a retinal gene which is mutated in progressive rod-cone degeneration, but in the opposite orientation.

Genbezeichner und Symbole assoziert mit anti-Cytoglobin (CYGB) Antikörper

  • cytoglobin 1 (cygb1) Antikörper
  • cytoglobin (cygb) Antikörper
  • cytoglobin (CYGB) Antikörper
  • cytoglobin-1 (cygb1) Antikörper
  • cytoglobin L homeolog (cygb.L) Antikörper
  • cytoglobin (Cygb) Antikörper
  • 3110001K20Rik Antikörper
  • CYGB Antikörper
  • cygb-1 Antikörper
  • HGB Antikörper
  • MGC84306 Antikörper
  • MGC89562 Antikörper
  • Staap Antikörper
  • Stap Antikörper
  • wu:fb77d07 Antikörper
  • wu:fb93a03 Antikörper
  • zgc:109806 Antikörper

Bezeichner auf Proteinebene für anti-Cytoglobin (CYGB) Antikörper

cyt , cytoglobin-1 , cytoglobin , histoglobin , stellate cell activation associated protein , stellate cell activation-associated protein , HGb

246090 Danio rerio
448640 Xenopus (Silurana) tropicalis
707130 Macaca mulatta
739843 Pan troglodytes
100049376 Oryzias latipes
100136084 Oncorhynchus mykiss
100307038 Ovis aries
447575 Xenopus laevis
100224652 Taeniopygia guttata
100357278 Oryctolagus cuniculus
114886 Mus musculus
114757 Homo sapiens
427802 Gallus gallus
609341 Canis lupus familiaris
510299 Bos taurus
170520 Rattus norvegicus
100058726 Equus caballus
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