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Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Proteine (CYP2E1)

CYP2E1 encodes a member of the cytochrome P450 superfamily of enzymes. Zusätzlich bieten wir Ihnen Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Antikörper (177) und Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Kits (42) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CYP2E1 1571 P05181
CYP2E1 13106 Q05421
CYP2E1 25086 P05182
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Showing 10 out of 22 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 57 Days
7.380,00 €
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Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 57 Days
7.380,00 €
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HOST_Escherichia coli (E. coli) Ratte His tag 100 μg Anmelden zum Anzeigen 9 bis 12 Tage
784,67 €
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HOST_Wheat germ Human GST tag 2 μg Anmelden zum Anzeigen 8 bis 9 Tage
235,20 €
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Hefe Macaca fascicularis His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.104,45 €
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Hefe Mesocricetus auratus His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.231,90 €
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Hefe Macaca mulatta His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.231,90 €
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Hefe Kaninchen His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.231,90 €
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Hefe Hund His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.235,40 €
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Hefe Rind (Kuh) His tag   1 mg Anmelden zum Anzeigen 54 bis 65 Tage
3.237,14 €
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CYP2E1 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , ,
, ,
Mouse (Murine) ,

Rat (Rattus) ,

Weitere Proteine zu Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartnern

Rabbit Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. The localization of CYP1A2 (zeige CYP1A2 Proteine), CYP2B4 and CYP2E1 within the ER was determined by partial membrane solubilization with Brij 98

Human Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. The CYP2E1-PPARalpha (zeige PPARA Proteine) axis may play a role in ethanol-induced neurotoxicity via the alteration of the genes related with synaptic function

  2. Results demonstrated that CYP2E1*5B and CYP2E1*6 minor alleles play a role in the development of sporadic colorectal neoplasms.

  3. This meta-analysis suggests that there is an increased risk of antituberculosis drug-induced hepatotoxicity in individuals carrying the C1/C1 genotype of the CYP2E1 RsaI/PstI (zeige SPINK1 Proteine) polymorphism; however, no association was found for the DraI polymorphism

  4. NS5A contributes to reactive oxygen species production by activating expression of NADPH (zeige NQO1 Proteine) oxidases 1 and 4 as well as cytochrome P450 2E1.

  5. This meta-analysis suggests that the CYP2E1 polymorphisms contributed to the susceptibility of nasopharyngeal carcinoma, especially in Asian populations.

  6. Study indicate that ALDH2 (zeige ALDH2 Proteine) Glu487Lys and CYP4502E1 polymorphisms could be risk factors for the development of gastric cancer in the Chinese population.

  7. genetic association studies in population in Italy: Data suggest that SNPs in CYP2E1 are associated with differentiated thyroid carcinoma.

  8. CYP2E1 RsaI/PstI (zeige SPINK1 Proteine) polymorphisms may modify the susceptibility to HNC (zeige MMP8 Proteine), particularly among Asians, mixed population, and never-smokers.

  9. CYP2E1 rs2031920 and COMT (zeige COMT Proteine) rs4680 are not major contributors to lung cancer risk.

  10. Single nucleotide polymorphism in CYP2E1 gene is Associated with Breast Cancer.

Mouse (Murine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. Data, including data from studies in knockout mice, suggest that the oxidative metabolism of 1,2-dichloropropane, a carcinogenic solvent/insecticide, is exclusively catalyzed by Cyp2e1; this biotransformation step is indispensable for manifestation of hepatotoxic effect of the solvent.

  2. Taken together, these results suggested that 1,2-dichloroethane (1,2-DCE (zeige DHCR24 Proteine)) could enhance CYP2E1 protein expression and enzymatic activity, which could cause oxidative damage in liver, serving as an important mechanism underlying 1,2-DCE (zeige DHCR24 Proteine)-induced liver damage

  3. CYP2E1 is important in causing aging-dependent hepatic steatosis, apoptosis and fibrosis possibly through increasing nitroxidative stress.

  4. Our results support a significant role for CYP2E1 as a novel 4-Aminobiphenyl N-oxidizing enzyme in adult mice

  5. Schisandrol B protects against APAP-induced liver injury, potentially through inhibition of CYP2E1/3A11-mediated APAP bioactivation and regulation of the p53 (zeige TP53 Proteine), p21, CCND1 (zeige CCND1 Proteine), PCNA (zeige PCNA Proteine), and BCL-2 (zeige BCL2 Proteine) to promote liver regeneration.

  6. Studied hepatic stellate cell cytoglobin (zeige CYGB Proteine) involvement in acetaminophen induced hepatotoxicity through the regulation of CYP2E1.

  7. Data suggest that expression of Cyp2e1 in adipose tissue can be regulated by dietary factors; here, expression of Cyp2e1 in white adipose tissue is down-regulated in obesity caused by high-fat diet.

  8. The Cyp2e1-null mice displayed a susceptibility to lung toxicity of styrene similar to that of the wild-type animals; however, Cyp2f2-null mice were resistant to styrene-induced pulmonary toxicity.

  9. significant increases in Col1a1 (zeige COL1A1 Proteine), serine/threonine-protein kinase 1, Ctnnb1 (zeige CTNNB1 Proteine), CSRNP1 (zeige CSRNP1 Proteine), Ddit4 (zeige DDIT4 Proteine), Cyp2e1, and Krit1 (zeige KRIT1 Proteine) expressions and great decreases inreceptor D2, Neu1 (zeige NEURL Proteine), and Dhcr7 (zeige DHCR7 Proteine) expressions following long-term exposure to TiO2 NPs (zeige NPS Proteine)

  10. ATF4 (zeige ATF4 Proteine) expression in the liver is responsible for the protective effects against high fat diet-induced CYP2E1 expression.

Pig (Porcine) Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Interaktionspartner

  1. A highly significant association was found between variation in skatole levels and SNPs within the CYP2E1 gene on chromosome 14.

  2. The relationship between a single nucleotide polymorphism of CYP2E1 and boar taint in pork from Belgian swine is reported.

Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1) Protein Überblick

Protein Überblick

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines which are premutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.

Genbezeichner und Symbole assoziert mit CYP2E1

  • cytochrome P450, family 2, subfamily E, polypeptide 1 (CYP2E1)
  • cytochrome P450 2E1 (CYP2E1)
  • cytochrome P450 2E1 (PTRG_07411)
  • Cytochrome P450 2E1-like (LOC100342572)
  • cytochrome P450 2E1-like (LOC100727914)
  • cytochrome P450 2E1-like (LOC101843716)
  • cytochrome P450, family 2, subfamily e, polypeptide 1 (Cyp2e1)
  • CPE1 Protein
  • Cyp2e Protein
  • CYP2E1 Protein
  • CYPIIE1 Protein
  • P450-J Protein
  • P450C2E Protein

Bezeichner auf Proteinebene für CYP2E1

cytochrome P450 2E1 , 4-nitrophenol 2-hydroxylase , Cytochrome P450 2E1 , Cytochrome P450 LM3A , Cytochrome P450 isozyme 3A , Cytochrome P450-ALC , Cytochrome P450-J , cytochrome P-450j , CYPIIE1 , cytochrome P450, subfamily IIE (ethanol-inducible), polypeptide 1 , cytochrome P450-J , flavoprotein-linked monooxygenase , microsomal monooxygenase , xenobiotic monooxygenase , cytochrome P450, 2e1, ethanol inducible , cytochrome P450-ALC , P450-J , P450RLM6 , cytochrome P450 subfamily 2e1 (ethanol-inducible) , cytochrome P450, subfamily 2E, polypeptide 1 , cytochrome P450RLM6 , cytochrome P-450-J , cytochrome P450 CYP2E1

GENE ID SPEZIES
100066422 Equus caballus
554344 Felis catus
6345684 Pyrenophora tritici-repentis Pt-1C-BFP
100342572 Oryctolagus cuniculus
100727914 Cavia porcellus
101843716 Mesocricetus auratus
1571 Homo sapiens
415128 Canis lupus familiaris
13106 Mus musculus
25086 Rattus norvegicus
403216 Sus scrofa
282213 Bos taurus
100568285 Ovis aries
678688 Macaca mulatta
Ausgewählte Anbieter für Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 Proteine (CYP2E1)
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