Cytidine Deaminase Proteine (CDA)

CDA encodes an enzyme involved in pyrimidine salvaging. Zusätzlich bieten wir Ihnen CDA Antikörper (83) und CDA Kits (15) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CDA 978 P32320
CDA 72269 P56389
Ratte CDA CDA 362638  
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 50 Days
Escherichia coli (E. coli) Human His tag 100 μg Anmelden zum Anzeigen 2 bis 3 Tage
Wheat germ Human GST tag 10 μg Anmelden zum Anzeigen 11 bis 12 Tage
Hefe REACT_Mycoplasma pneumoniae His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe REACT_Yersinia pseudotuberculosis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Serratia proteamaculans His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Salmonella arizonae His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe Pasteurella multocida His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage
Hefe REACT_Proteus mirabilis His tag   1 mg Anmelden zum Anzeigen 60 bis 71 Tage

CDA Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , ,
, ,
Mouse (Murine)

Weitere Proteine zu Cytidine Deaminase (CDA) Interaktionspartnern

Human Cytidine Deaminase (CDA) Interaktionspartner

  1. The observed incomplete sister chromatid disjunction may be due to the accumulation of unreplicated DNA during mitosis in CDA-deficient cells, as reflected in the changes in centromeric DNA structure associated with the decrease in basal PARP-1 (zeige PARP1 Proteine) activity.

  2. Intracerebral microdialysis revealed that clonal NSC line to stably express cytosine deaminase (CD-NSCs) produced 5-FU locally in the brain in a 5-FC dose-dependent manner. Collectively, our results from this first-in-human study demonstrate initial safety and proof of concept regarding the ability of NSCs to target brain tumors and locally produce chemotherapy.

  3. results indicate that rs2072671 in CDA may be an important prognostic marker in NK-AML (zeige RUNX1 Proteine) patients.

  4. tumor cell lines that are susceptible to epigenetic nucleosides overexpress cytidine deaminase (CDA); CDA converts 5hmdC and 5fdC into variants of uridine that are incorporated into DNA, resulting in accumulation of DNA damage, and ultimately, cell death

  5. RNA expression of deoxycytidine kinase (DCK (zeige DCK Proteine)), human equilibrative nucleoside transporter-1 (ENT1 (zeige SLC29A1 Proteine)) and ribonucleotide reductase M1 (RRM1 (zeige RRM1 Proteine)) were significantly higher and cytidine deaminase (CDA) was significantly lower in ex vivo Ara (zeige FOXC1 Proteine)-C sensitive samples.

  6. stimulation of PARP-1 (zeige PARP1 Proteine) activity in CDA-deficient cells restores replication and, thus, chromosome segregation. Moreover, increasing intracellular dCTP levels generates under-replication-induced sister-chromatid bridges as efficiently as PARP-1 (zeige PARP1 Proteine) knockdown

  7. n the multivariate Cox (zeige COX8A Proteine) regression analysis, we found that age at diagnosis, wild-type genotype of the CDA A79C polymorphism, and wild-type genotype of the dCK (zeige DCK Proteine) C360G polymorphism were the most significant prognostic factors for predicting the risk of death

  8. Single nucleotide polymorphisms in cytidine deaminase gene were associated with the efficacy of gemcitabine in Biliary Tract Cancer.

  9. Polymorphisms in ABCB1 (zeige ABCB1 Proteine), CDA, ENOSF1 (zeige ENOSF1 Proteine),and TYMS (zeige TYMS Proteine) could help to predict specific and overall severe adverse reactions to capecitabine.

  10. miR (zeige MLXIP Proteine)-484-modulated cytidine deaminase has a dual impact in promoting chemoresistance and suppressing cell proliferation in breast cancer

Mouse (Murine) Cytidine Deaminase (CDA) Interaktionspartner

  1. Data indicate that a combination cytosine deaminase (CDA)/uracil phosphoribosyltransferase (zeige UPP Proteine) protein (UPRT (zeige UPRT Proteine))-expressing adipose tissue-derived mesenchymal stem cells (AT-MSCs) with lysomustine has a superior antitumor effect in the lung carcinoma model compared to monotherapies with transfected AT-MSCs or lysomustine alone.

  2. Activation-induced cytidine deaminase (zeige AICDA Proteine) plays an important role in the containment of autoimmune diseases by negative regulation of autoreactive B cells.

CDA Protein Überblick

Protein Überblick

This gene encodes an enzyme involved in pyrimidine salvaging. The encoded protein forms a homotetramer that catalyzes the irreversible hydrolytic deamination of cytidine and deoxycytidine to uridine and deoxyuridine, respectively. It is one of several deaminases responsible for maintaining the cellular pyrimidine pool. Mutations in this gene are associated with decreased sensitivity to the cytosine nucleoside analogue cytosine arabinoside used in the treatment of certain childhood leukemias.

Genbezeichner und Symbole assoziert mit Cytidine Deaminase Proteine (CDA)

  • cytidine deaminase (CDA)
  • cytidine deaminase (cda)
  • cytidine deaminase (VNG_RS03500)
  • cytidine deaminase (OE_RS03485)
  • cytidine deaminase (CDD1)
  • cytidine aminohydrolase; CDA (cdd)
  • cytidine deaminase b (cdab)
  • Cytidine deaminase (cdd-1)
  • Cytidine deaminase (cdd-2)
  • cytidine deaminase Cdd (cdd)
  • cytidine deaminase (CNC04940)
  • cytidine deaminase (Tb09.160.1680)
  • cytidine deaminase (Cda)
  • 2210401N16Rik Protein
  • cda Protein
  • CDD Protein
  • DDBDRAFT_0188181 Protein
  • DDBDRAFT_0230205 Protein
  • DDB_0188181 Protein
  • DDB_0230205 Protein
  • zgc:77948 Protein

Bezeichner auf Proteinebene für Cytidine Deaminase Proteine (CDA)

cytidine deaminase , CytiDine Deaminase family member (cdd-1) , CytiDine Deaminase family member (cdd-2) , cytidine aminohydrolase , cytosine nucleoside deaminase , small cytidine deaminase

705913 Macaca mulatta
549971 Xenopus (Silurana) tropicalis
487393 Canis lupus familiaris
616377 Bos taurus
1447638 Halobacterium sp. NRC-1
5954454 Halobacterium salinarum R1
5719128 Chlamydomonas reinhardtii
3431029 Haemophilus influenzae 86-028NP
402979 Danio rerio
771849 Gallus gallus
744046 Pan troglodytes
8626880 Dictyostelium discoideum AX4
183546 Caenorhabditis elegans
186044 Caenorhabditis elegans
1170491 Shewanella oneidensis MR-1
3256143 Cryptococcus neoformans var. neoformans JEC21
3660189 Trypanosoma brucei brucei strain 927/4 GUTat10.1
978 Homo sapiens
72269 Mus musculus
362638 Rattus norvegicus
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