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putative cysteinyl leukotriene receptor [RGD, Feb 2006].. Zusätzlich bieten wir Ihnen CasLTR2 Antikörper (67) und CasLTR2 Kits (49) und viele weitere Produktgruppen zu diesem Protein an.
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our study identifies CYSLTR2 L129Q alterations as a previously unrecognized activating mutation in blue nevi, occuring in a mutually exclusive fashion with known GNAQ (zeige GNAQ Proteine) and GNA11 (zeige GNA11 Proteine) mutations.
The expression of CysLTR1 (zeige CYSLTR1 Proteine) and CysLTR2 is higher in the lymphocytes of hyperplasic tonsils in nonallergic children
findings implicate CYSLTR2 as a uveal melanoma oncogene (zeige RAB1A Proteine) and highlight the critical role of Galphaq (zeige GNAQ Proteine) signaling in uveal melanoma pathogenesis
CysLT2 receptors were expressed in lung specimens isolated from asthma subjects. Activation of CysLT2 receptors may contribute to antigen-induced bronchoconstriction in certain asthma population.
CysLTR-1 (zeige CYSLTR1 Proteine) and CysLTR-2 are highly expressed in the adenoid tissues from children with AH, suggesting that leukotrienes are involved in the pathogenesis of AH.
Suggest that endothelial and nonendothelial CysLT2R niches have separate roles in mediating inflammatory responses in ischemic/perfusion injury.
ATRA treatment induces CysLT(2)R mRNA and protein expression in colon cancer cell lines
CysLT2 receptor plays a primary role in the vascular responses in the upper respiratory tract.
There is a protective role against tumor progression for CysLT(2)R and that it highlights new possibilities to regulate the CysLT(2)R.
The synthesis of cys (zeige DNAJC5 Proteine)-LTs from LTA (zeige LTA Proteine)(4) by endothelial cells is directly associated with the activation of the CysLT(2) receptor in a typical autocrine fashion.
CysLT2R signaling, IL-33 (zeige IL33 Proteine)-dependent group 2 innate lymphoid cell expansion, and IL-33 (zeige IL33 Proteine)-driven mast cell activation are necessary for induction of type 2 immunopathology and aspirin sensitivity. CysLT2R-targeted drugs may interrupt these processes.
The CysLT(1 (zeige CYSLTR1 Proteine)) and CysLT(2) receptors were primarily localized in neurons, microglia and neutrophils
LTC4 activates mouse platelets exclusively through CysLT2R. LTC4/CysLT2R signaling required an autocrine ADP-mediated response through P2Y12 (zeige P2RY12 Proteine) receptors.
CysLT1R (zeige CYSLTR1 Proteine), CysLT2R and GPR17 (zeige GPR17 Proteine) might be involved in the MPTP (zeige PTPN2 Proteine)-induced Parkinson disease damage in mice.
CysLT2R negatively regulates the development of cys (zeige DNAJC5 Proteine)-LT-dependent T helper cell (Th)2 pulmonary inflammation by inhibiting both CysLT1R (zeige CYSLTR1 Proteine) signaling and house dust mite-induced LTC4S (zeige LTC4S Proteine)-dependent cell surface expression of CysLT1R (zeige CYSLTR1 Proteine) on dendritic cells.
These findings establish a role for eosinophil-derived cysteinyl leukotriene and the CysLT(2)R in the hyperkeratosis and fibrosis of allergic skin inflammation.
Results implicate the CysLT(2)R in the progression of ischemic retinopathy.
These results suggest that a lack of neuronal expression of CysLTR (zeige CYSLTR1 Proteine) in the murine colonic myenteric plexus attenuates colitis disease progression.
findings show that CysLT1 receptor (zeige CYSLTR1 Proteine) attenuates while CysLT2 receptor facilitates oxygen glucose deprivation -induced PC12 cell death
In luteal-phase endometrium, expression of 5-LO (5-lipoxygenase (zeige ALOX5 Proteine)) and LTB4R (leukotriene B4 receptor) is highest on Days 2-4; expression of LTCS (leukotriene-C4 synthase (zeige LTC4S Proteine)) and CysLTR2 (cysteinyl leukotriene receptor 2) is highest on Days 16-18. In luteal-phase endometrium, LTB4 (zeige PTGR1 Proteine) level is highest on Days 2-4; LTC4 level is highest on Days 16-18. Studies were conducted in Poland on Holstein Polish Black and White dairy cows.
putative cysteinyl leukotriene receptor
cysteinyl leukotriene receptor 2
, G protein-coupled receptor
, G-protein coupled receptor GPCR21
, G-protein coupled receptor HG57
, cysteinyl leukotriene CysLT2 receptor