Cystatin C Proteine (CST3)

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Zusätzlich bieten wir Ihnen Cystatin C Antikörper (461) und Cystatin C Kits (121) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CST3 1471 P01034
CST3 13010 P21460
CST3 25307 P14841
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Katalog Nr. Origin Quelle Konjugat Bilder Menge Anbieter Lieferzeit Preis Details
Human Cells Human His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
Human Cells Maus His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Escherichia coli (E. coli) Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Anmelden zum Anzeigen 30 bis 35 Tage
Human Cells Human Unkonjugiert 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
HEK-293 Cells Human Unkonjugiert 50 μg Anmelden zum Anzeigen 2 bis 3 Tage
Human Cells Ratte His tag 10 μg Anmelden zum Anzeigen 20 bis 21 Tage
Escherichia coli (E. coli) Hund His tag 50 μg Anmelden zum Anzeigen 13 bis 16 Tage
Escherichia coli (E. coli) Huhn His tag 100 μg Anmelden zum Anzeigen 15 bis 18 Tage
Escherichia coli (E. coli) Human His tag   50 μg Anmelden zum Anzeigen 4 Days

CST3 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human , , , , , ,
, ,
Mouse (Murine) , ,
Rat (Rattus) , ,

Weitere Proteine zu Cystatin C (CST3) Interaktionspartnern

Human Cystatin C (CST3) Interaktionspartner

  1. Cystatin C may be considered a biological marker for vascular dysfunction and subclinical atherosclerosis in SCD (zeige SCD Proteine).

  2. Serum cystatin C level was significantly associated with subclinical atherosclerosis. An increase in cystatin C level could be a valuable surrogate marker for the risk of cardiovascular disease in patients with type 2 diabetes mellitus.

  3. Mild-to-moderate kidney dysfunction modifies the relationship between CysC and high-risk coronary lesion, but not NGAL (zeige LCN2 Proteine).

  4. Increasing cystatin C and cathepsin B (zeige CTSB Proteine) reported in serum of colorectal cancer patients.

  5. Both cystatin C and beta 2 macroglobulin are elevated in type 2 diabetics with diabetic nephropathy. Cystatin C may be useful in the early diagnosis of diabetic nephropathy

  6. Results from nuclear magnetic resonance structural data and molecular dynamics modeling point to conformational requirements and special importance of some amino acid residues in cystatin 3 C-terminal for the its interaction with amyloid beta fragments.

  7. The findings of the current studies may be important for future design of hCC (zeige FAM126A Proteine) dimerization inhibitors.

  8. High cystatin C was associated with increased risk of mortality but not with poor functional outcome in patients with acute intracerebral hemorrhage.

  9. this results identified cystatin 3 as a biomarker in patients with seasonal allergic rhinitis

  10. Serum and urine levels of cystatin C were significantly higher in children with acute kidney injury. [Review and Meta-Analysis]

Mouse (Murine) Cystatin C (CST3) Interaktionspartner

  1. CysC plays an important regulatory role in combating cell death via the autophagic pathway in atherosclerosis.

  2. Data (including data from studies in mutant mice) suggest that up-regulation of Cst3, as observed in plasma of mice with type 2 diabetes, down-regulates insulin (zeige INS Proteine) signaling and promotes endoplasmic reticulum stress in hepatocytes but not in myotubes.

  3. Cystatin C is a potential pathogenic signal triggering neurodegeneration in multiple system atrophy.

  4. The neuroprotective activity of CysC against Amyotrophic lateral sclerosis-linked mutant Cu/Zn-superoxide dismutase (SOD1 (zeige SOD1 Proteine))-mediated toxicity.

  5. an important role for macrophages, DC, and ROS (zeige ROS1 Proteine) in diseases associated with the protease inhibitory activity or amyloidogenic properties of cystatin C.

  6. APP (zeige APP Proteine) expression stimulates NSPC proliferation; this effect is mediated via an increase in cystatin C secretion

  7. Cystatin C, a protein targeted to the classical secretory pathway by its signal peptide sequence, is secreted by primary neurons in at least 9 different cystatin C glycoforms associated with exosomes.

  8. The lack of cystatin C enhances Collagen-induced arthritis and primarily affects in vivo priming of the immune system

  9. Inflammation causes downregulation of cystatin C expression in dendritic cells and reduces serum CstC levels.

  10. Data show that the absence of cystatin C reduced epithelial cell apoptosis but increased proliferation in skin.

Pig (Porcine) Cystatin C (CST3) Interaktionspartner

  1. CST3 may be required to remodel endometrial and placental tissues for close apposition between maternal and fetal vasculatures and to facilitate transplacental transport of gases, micronutrients (amino acids, glucose), and macromolecules (proteins).

Rabbit Cystatin C (CST3) Interaktionspartner

  1. Increased production of cystatin C in osteoarthritis synovium does not alleviate synovitis or cartilage pathology.

Cow (Bovine) Cystatin C (CST3) Interaktionspartner

  1. Cystatin C in milk basic protein (MBP (zeige MBP Proteine)) is suggested as one of the factors inhibiting bone resorption

Cystatin C (CST3) Protein Überblick

Protein Überblick

The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions, where they appear to provide protective functions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes the most abundant extracellular inhibitor of cysteine proteases, which is found in high concentrations in biological fluids and is expressed in virtually all organs of the body. A mutation in this gene has been associated with amyloid angiopathy. Expression of this protein in vascular wall smooth muscle cells is severely reduced in both atherosclerotic and aneurysmal aortic lesions, establishing its role in vascular disease.

Genbezeichner und Symbole assoziert mit Cystatin C Proteine (CST3)

  • cystatin C (CST3)
  • cystatin C L homeolog (cst3.L)
  • cystatin C (amyloid angiopathy and cerebral hemorrhage) (cst3)
  • cystatin C (cst3)
  • cystatin 3 (cystatin 3)
  • cystatin C (Cst3)
  • ARMD11 Protein
  • CYSC Protein
  • fb51d07 Protein
  • wu:fb24g06 Protein
  • wu:fb51d07 Protein
  • wu:fc55f03 Protein
  • zgc:136227 Protein

Bezeichner auf Proteinebene für Cystatin C Proteine (CST3)

cystatin , egg-white cystatin , ovocystatin , cystatin C , cystatin-C , cystatin 3 , hypothetical protein , bA218C14.4 (cystatin C) , cystatin-3 , gamma-trace , neuroendocrine basic polypeptide , post-gamma-globulin , Cystatin C (cysteine proteinase inhibitor) , colostrum thiol proteinase inhibitor , cystatin C (amyloid angiopathy and cerebral hemorrhage)

396497 Gallus gallus
733234 Xenopus laevis
791878 Danio rerio
100379852 Xenopus (Silurana) tropicalis
100462660 Felis catus
3238896 Cotesia congregata bracovirus
1471 Homo sapiens
13010 Mus musculus
733672 Sus scrofa
25307 Rattus norvegicus
100009450 Oryctolagus cuniculus
281102 Bos taurus
574313 Macaca mulatta
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