Cyclin-Dependent Kinase 13 Proteine (CDK13)

The protein encoded by CDK13 is a member of the cyclin-dependent serine/threonine protein kinase family. Zusätzlich bieten wir Ihnen CDK13 Antikörper (37) und viele weitere Produktgruppen zu diesem Protein an.

alle Proteine anzeigen Gen GeneID UniProt
CDK13 8621 Q14004
CDK13 69562 Q69ZA1
Ratte CDK13 CDK13 306998  
Direkt bei antikoerper-online bestellen
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Online bestellen

Top CDK13 Proteine auf

Showing 3 out of 4 products:

Katalog Nr. Origin Quelle Konjugat Bilder Menge Lieferzeit Preis Details
Insektenzellen Maus His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Insektenzellen Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg 70 Days
Wheat germ Human GST tag 10 μg 11 bis 12 Tage

CDK13 Proteine nach Spezies und Herkunft

Origin Exprimiert in Konjugat
Human ,
Mouse (Murine)

Weitere Proteine zu Cyclin-Dependent Kinase 13 (CDK13) Interaktionspartnern

Human Cyclin-Dependent Kinase 13 (CDK13) Interaktionspartner

  1. We demonstrate the synthesis of two aberrant CDK13 transcripts in lymphoblastoid cells from an individual with a splice-site variant. Clinical characteristics of the individuals include mild to severe intellectual disability (ID), developmental delay, behavioural problems, (neonatal) hypotonia and a variety of facial dysmorphism.

  2. CDK13 is important for proper expression of a number of genes, but it also probably plays yet-to-be-discovered roles in other processes.

  3. Heterozygous constitutional CDK13 mutations in 3 patients cause intellectual disability without cardiac defects.

  4. CDK13 RNA over-editing sites mediated by ADAR1 may serve as novel cancer driver events in HCC progression.

  5. heterozygous, likely dominant negative mutations affecting the protein kinase domain of the CDK13 gene result in a recognisable, syndromic form of intellectual disability, with or without congenital heart disease.

  6. Mutation in CHK13 gene is associated with congenital heart defects.

  7. Detailed phenotypic and molecular characterisation of 9 individuals with pathogenic variants in CDK13 is provided. Two individuals had novel CDK13 variants (p.Asn842Asp, p.Lys734Glu), while the remaining seven unrelated individuals had a recurrent, previously published p.Asn842Ser variant.

  8. CDK13 gene is amplified in different types of cancer indicate that this kinase can contribute to cancer development in human.

  9. CDK12 and CDK13 losses in HCT116 cells preferentially affect expression of DNA damage response.

  10. High CDK13 expression is associated with pancreatic cancer.

  11. Coincidently amplified CDK13, GMNN, and CENPF genes can play a role as common cancer-driver genes in human cancers.

  12. CDK13 interacts with cyclin K, and is required for self-renewal in ES cells.

  13. Data demonstrate that CDC2L5 is located in the nucleoplasm, where it directly interacts with the ASF/SF2-associated protein p32, a protein involved in splicing regulation.

Mouse (Murine) Cyclin-Dependent Kinase 13 (CDK13) Interaktionspartner

  1. The findings of this study suggest that Cdk12 and Cdk13 regulate axonal elongation through a common signaling pathway that modulates Cdk5 expression.

CDK13 Protein Überblick

Protein Überblick

The protein encoded by this gene is a member of the cyclin-dependent serine/threonine protein kinase family. Members of this family are well known for their essential roles as master switches in cell cycle control. The exact function of this protein has not yet been determined, but it may play a role in mRNA processing and may be involved in regulation of hematopoiesis. Alternatively spliced transcript variants have been described.

Genbezeichner und Symbole assoziert mit CDK13

  • cyclin dependent kinase 13 (CDK13)
  • cyclin-dependent kinase 13 (cdk13)
  • cyclin-dependent kinase 13 (Cdk13)
  • 2310015O17Rik Protein
  • CDC2L Protein
  • Cdc2l5 Protein
  • CHED Protein
  • hCDK13 Protein
  • wu:fe16d10 Protein
  • wu:fi49c05 Protein

Bezeichner auf Proteinebene für CDK13

cell division cycle 2-like 5 (cholinesterase-related cell division controller) , cholinesterase-related cell division controller , fi49c05 , cyclin-dependent kinase 13 , CDC2-related protein kinase 5 , cell division cycle 2-like protein kinase 5 , cell division protein kinase 13

420766 Gallus gallus
559027 Danio rerio
736969 Pan troglodytes
711379 Macaca mulatta
100589292 Nomascus leucogenys
8621 Homo sapiens
69562 Mus musculus
306998 Rattus norvegicus
475874 Canis lupus familiaris
511147 Bos taurus
Ausgewählte Anbieter für CDK13 Proteine (CDK13)
Haben Sie etwas anderes gesucht?