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The protein encoded by CDK10 belongs to the CDK subfamily of the Ser/Thr protein kinase family. Zusätzlich bieten wir Ihnen CDK10 Proteine (6) und CDK10 Kits (1) und viele weitere Produktgruppen zu diesem Protein an.
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Human Polyclonal CDK10 Primary Antibody für IHC (p), WB - ABIN391741
Leman, Magheli, Yong, Netto, Hinz, Getzenberg: Identification of nuclear structural protein alterations associated with seminomas. in Journal of cellular biochemistry 2009
Show all 11 Pubmed References
cdk10 has roles in vertebrate development and a critical function in neurogenesis by modulation of raf1a (zeige RAF1 Antikörper) expression
CDK10 Mutations are associated with Severe Growth Retardation, Spine Malformations, and Developmental Delays.
CDK10/CycM is a key regulator of actin dynamics and a suppressor of ciliogenesis through phosphorylation of PKN2 (zeige PKN2 Antikörper) and promotion of RhoA (zeige RHOA Antikörper) signaling.
Down-regulated CDK10 expression frequently occurs in breast cancers and correlates with disease progression and poor survival
Results found that CDK10 mRNA expression was up-regulated in advanced breast neoplasm and positively correlated with C1orf63, which was consistent with the relationship of protein expression between C1orf63 and CDK10.
Data suggest that reactivation of CDK10 might be utilized as a novel epigenetic strategy for the treatment of nasopharyngeal carcinomas (NPC (zeige NPC1 Antikörper)) patients.
CDK10/cyclin M (zeige CCNL2 Antikörper) is a protein kinase (zeige CDK7 Antikörper) that controls ETS2 (zeige ETS2 Antikörper) degradation and is deficient in STAR syndrome.
Data show that peptidyl-prolyl isomerase Pin1 sil (zeige PIN1 Antikörper)encing in SKBR-3 and MCF7 cells increased the cyclin-dependent kinase 10 (CDK10) expression.
CDK10 plays a crucial role in the growth and survivability of biliary tract cancer.
reduced Cdk10 expression is closely linked to hepatocellular carcinoma development and progression
CDK10 is not a target for aberrant DNA methylation (zeige HELLS Antikörper) in breast cancer.
Data indicate that peptidyl-prolyl isomerase Pin1 (zeige PIN1 Antikörper)(-/-) mouse embryonic fibroblasts (MEFs) showed higher cyclin-dependent kinase 10 (CDK10) expression than Pin1 (zeige PIN1 Antikörper)(+/+) MEFs.
Data show that murine cdk10 binds Ets2 (zeige ETS2 Antikörper) transcription factors in vitro, does not show a direct involvement in the G2/M transition and, therefore, does not affect the proliferation rate of the cell lines analyzed.
Discusses PISSLRE, the human ortholog of mouse cyclin-dependent kinase 10.
The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene.
cell division protein kinase 10
, PITSLRE subfamily protein kinase
, protein kinase, CMGC group
, cyclin-dependent kinase 10
, cell division protein kinase 10-like
, cyclin-dependent kinase (CDC2-like) 10
, hypothetical protein
, CDC2-related protein kinase
, cyclin-dependent kinase related protein
, serine/threonine protein kinase PISSLRE
, serine/threonine-protein kinase PISSLRE
, cyclin dependent kinase 10