Cyclin G Associated Kinase (GAK) ELISA Kits

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Zusätzlich bieten wir Ihnen GAK Antikörper (97) und GAK Proteine (6) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
GAK 2580 O14976
GAK 231580 Q99KY4
GAK 81659 P97874
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Maus
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Human
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Weitere ELISA Kits für GAK Interaktionspartner

Human Cyclin G Associated Kinase (GAK) Interaktionspartner

  1. that the multiple single nucleotide polymorphisms of GAK synergistically participate in the pathogenesis of sporadic Parkinson's disease through multiple pathways.

  2. We have demonstrated that siRNA-mediated GAK silencing causes marked cell cycle disruption resulting in a raised sub-G1 alongside decreased G1 and G2/M cell cycle phases. Dual FBXW7 (zeige FBXW7 ELISA Kits)-GAK inhibition increases multipolar mitoses

  3. GAK gene expression is increased in Parkinson disease

  4. We filtered four OSCC genes including SERPINB9 (zeige SERPINB9 ELISA Kits), SERPINE2 (zeige SERPINE2 ELISA Kits), GAK, and HSP90B1 (zeige HSP90B1 ELISA Kits) through the gene global prioritization score (P < 0.005).

  5. This meta-analysis suggests that GAK rs1564282 C/T polymorphism is associated with increased susceptibility to Parkinson's disease--{REVIEW}

  6. Data indicated that GBA (zeige GBA ELISA Kits) and TMEM175/GAK significantly alter age at onset in PD.

  7. AAK1 and GAK are critical regulators of HCV entry that function in part by activating EGFR, AP2M1, and NUMB, and as the molecular targets underlying the antiviral effect of sunitinib and erlotinib, respectively.

  8. The effects of rs11248051 and rs1564282 variants of GAK, and the rs3129882 variant of HLA-DRA (zeige HLA-DRA ELISA Kits), were investigated in Parkinson's disease patients.

  9. GAK apo (zeige C9orf3 ELISA Kits) structure reveals a dimeric inactive state of the catalytic domain mediated by an unusual activation segment interaction.

  10. Cyclin-G-associated kinase is a binding partners of LRRK2, a candidate genes for risk for sporadic Parkinson disease, and part of a complex that promotes clearance of Golgi-derived vesicles through the autophagy-lysosome system.

Mouse (Murine) Cyclin G Associated Kinase (GAK) Interaktionspartner

  1. PTEN-like domains of GAK and auxilin are not essential for Hsc70-dependent chaperoning and uncoating of clathrin, but depending on the tissue, these domains appear to increase the efficiency of these co-chaperones.

  2. GAK knockout causes senescence and centrosome duplication in MEF cells.

  3. These results suggest that inhibition of GAK by gefitinib may cause pulmonary alveolar dysfunction.

  4. GAK deletion blocks development and causes lethality in adult animals by disrupting clathrin-mediated endocytosis

GAK Antigen-Profil

Beschreibung des Gens

In all eukaryotes, the cell cycle is governed by cyclin-dependent protein kinases (CDKs), whose activities are regulated by cyclins and CDK inhibitors in a diverse array of mechanisms that involve the control of phosphorylation and dephosphorylation of Ser, Thr or Tyr residues. Cyclins are molecules that possess a consensus domain called the 'cyclin box.' In mammalian cells, 9 cyclin species have been identified, and they are referred to as cyclins A through I. Cyclin G is a direct transcriptional target of the p53 tumor suppressor gene product and thus functions downstream of p53. GAK is an association partner of cyclin G and CDK5.

Genbezeichner und Symbole assoziert mit GAK

  • cyclin G associated kinase (GAK) Antikörper
  • cyclin G associated kinase (gak) Antikörper
  • cyclin G associated kinase (Gak) Antikörper
  • D130045N16Rik Antikörper
  • DKFZp469F1313 Antikörper
  • DNAJ26 Antikörper
  • DNAJC26 Antikörper
  • gak Antikörper
  • MGC172462 Antikörper
  • si:dkeyp-1e8.1 Antikörper

Bezeichner auf Proteinebene für GAK

cyclin G associated kinase , cyclin-G-associated kinase-like , auxilin-2 , cyclin-G-associated kinase , cyclin G-associated kinase

GENE ID SPEZIES
100051853 Equus caballus
100171982 Pongo abelii
549104 Xenopus (Silurana) tropicalis
461048 Pan troglodytes
703406 Macaca mulatta
571705 Danio rerio
100482527 Ailuropoda melanoleuca
2580 Homo sapiens
231580 Mus musculus
81659 Rattus norvegicus
427291 Gallus gallus
479133 Canis lupus familiaris
511296 Bos taurus
101106688 Ovis aries
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