Crystallin, alpha B (CRYAB) ELISA Kits

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. Zusätzlich bieten wir Ihnen CRYAB Antikörper (511) und CRYAB Proteine (30) und viele weitere Produktgruppen zu diesem Protein an.

list all ELISA KIts Gen GeneID UniProt
CRYAB 1410 P02511
CRYAB 12955 P23927
CRYAB 25420 P23928
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Top CRYAB ELISA Kits auf

Showing 10 out of 52 products:

Katalog Nr. Reaktivität Sensitivität Bereich Bilder Menge Anbieter Lieferzeit Preis Details
Human 3.12 pg/mL 12.5-800 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Huhn 5.86 pg/mL 23.44-1500 pg/mL Typical standard curve 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Maus 0.061 ng/mL 0.15 ng/mL - 10 ng/mL 96 Tests Anmelden zum Anzeigen 13 bis 16 Tage
Kaninchen 0.1 ng/mL 0.5-10 ng/mL 96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Ratte 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Rind (Kuh) 78-5000 pg/mL   96 Tests Anmelden zum Anzeigen 2 bis 3 Tage
Meerschweinchen 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
Schwein 0.094 ng/mL 0.156-10 ng/mL   96 Tests Anmelden zum Anzeigen 12 bis 14 Tage
Affe 0.1 ng/mL 0.5-10 ng/mL   96 Tests Anmelden zum Anzeigen 15 bis 18 Tage
  96 Tests Anmelden zum Anzeigen 2 bis 3 Tage

Am meisten referenzierte CRYAB ELISA Kits

  1. Human CRYAB ELISA Kit für Sandwich ELISA - ABIN2964835 : Baba, Oshitari, Yamamoto: Level of vitreous alpha-B crystallin in eyes with rhegmatogenous retinal detachment. in Graefe's archive for clinical and experimental ophthalmology 2015 (PubMed)

Weitere ELISA Kits für CRYAB Interaktionspartner

Human Crystallin, alpha B (CRYAB) Interaktionspartner

  1. Mechanistic studies revealed KLF4 (zeige KLF4 ELISA Kits) specifically bound the promoter of CRYAB and upregulated CRYAB expression in human osteosarcoma cells.

  2. mRNA levels of HSP family members (HSP70B', HSP72 (zeige HSPA1A ELISA Kits), HSP40/DNAJ (zeige DNAJB1 ELISA Kits), and HSP20 (zeige HSPB6 ELISA Kits)/CRYAB) are upregulated by the intracellular MMP3 (zeige MMP3 ELISA Kits) overload.

  3. HspB5 maybe trigger the epithelial-mesenchymal transition in colorectal cancer (CRC (zeige CALR ELISA Kits)) by activating the ERK (zeige EPHB2 ELISA Kits) signaling pathway. It is a potential tumor biomarker for CRC (zeige CALR ELISA Kits) diagnosis and prognosis.

  4. The CLN6 (zeige CLN6 ELISA Kits) is not only a molecular entity of the anti-aggregate activity conferred by the ER manipulation using TMalphaBC, but also serves as a potential target of therapeutic interventions.

  5. Results demonstrated that CRYAA (zeige CRYAA ELISA Kits) rs7278468 and CRYAB rs370803064/rs387907338 are correlated with the risk and clinicopathological features of children suffering from congenital cataract.

  6. A missense mutation in alpha B-crystallin that changes proline 20 to an arginine leads to diminished anti-apoptotic activity compared with the native protein.

  7. phosphorylation finely regulates the chaperone activity of CRYAB with multipass TMPs and suggest a pivotal role for S59 in this process

  8. A missense mutation (p.D109G) in CRYAB causes restrictive cardiomyopathy (RCM (zeige Unc5c ELISA Kits)).

  9. This work examines the molecular mechanism by which two canonical sHsps, alphaB-crystallin (alphaB-c) and Hsp27 (zeige HSPB1 ELISA Kits), interact with aggregation-prone alpha-syn to prevent its aggregation in vitro Both sHsps are very effective inhibitors of alpha-syn aggregation

  10. 343delT/343delT and WT KI/343delT-induced pluripotent stem cell-derived skeletal myotubes and cardiomyocytes did not express detectable levels of 343delT protein, contributable to the extreme insolubility of the mutant protein. Overexpression of HSPB5 343delT resulted in insoluble mutant protein aggregates and induction of a cellular stress response.

Mouse (Murine) Crystallin, alpha B (CRYAB) Interaktionspartner

  1. desmin and alphaBeta-crystallin are localized at sarcoplasmic reticulum (SR)-mitochondria-associated membranes (MAMs), where they interact with VDAC, Mic60 - the core component of mitochondrial contact site and cristae organizing system (MICOS) complex - and ATP synthase, suggesting that these associations could be crucial in mitoprotection at different levels.

  2. This study demonstrated that HspB5 mRNA localization in myelin-enriched white and gray matter

  3. alphaB-crystallin is an important regulator of epithelial-mesenchymal transition, acting as a molecular chaperone (zeige HSP90AA1 ELISA Kits) for SMAD4 (zeige SMAD4 ELISA Kits) and as its potential therapeutic target for preventing subretinal fibrosis development in neovascular age-related macular degeneration

  4. It is a non-Hsp gene, which is essential for HSF1 (zeige HSF1 ELISA Kits)-mediated maintenance of whole body homeostasis.

  5. A previously unrecognized link between c-Jun (zeige JUN ELISA Kits) and Nrf2 (zeige NFE2L2 ELISA Kits) transcription factors and redox-induced CRYAB expression in muscle cells.

  6. CryAB protects decidualization against stress conditions.

  7. TNF-alpha (zeige TNF ELISA Kits)-induced endothelial adhesion molecule (zeige NCAM1 ELISA Kits) expression is reduced in inflamed vessels of alphaB-crystallin deficient mice, and leukocyte rolling velocity and IkappaB levels are increased.

  8. Study shows that overexpression of Bcl-2 (zeige BCL2 ELISA Kits) is sufficient to reduce the levels and overall architecture of protein deposition in the transgenic CryABR120G/Bcl-2 (zeige BCL2 ELISA Kits) hearts.

  9. alphaB-crystallin is over-expressed in fibrotic lung tissue and favors TGF-beta1 (zeige TGFB1 ELISA Kits) pathway via its role in modulating the cellular localization of Smad4 (zeige SMAD4 ELISA Kits).

  10. Data suggest that Cryab plays role in embryo implantation/decidualization; on day 5 of pregnancy when embryo implantation takes place, high level of Cryab mRNA is expressed in subluminal stroma surrounding the implanting blastocyst.

Cow (Bovine) Crystallin, alpha B (CRYAB) Interaktionspartner

  1. The alphaB-crystallin content of bovine type I muscle fibers is quantitatively similar to that in the predominantly type I fibers of rat soleus muscle.

  2. In the presence of alpha-crystallin or GroEL the kinetic of GAPDH (zeige GAPDH ELISA Kits) aggregation is changed from the diffusion-limited cluster-cluster aggregation to the reaction-limited cluster-cluster aggregation.

  3. one of the functions of alphaB-crystallin is to bind microtubules via microtubule binding proteins and to give the MTs (zeige NEU2 ELISA Kits) resistance to disassembly

  4. The study provides evidence for the regulation of the chaperone activity of alphaB-crystallin by phosphorylation and indicates that this may play an important role in alleviating the pathogenic effects associated with protein conformational diseases.

Pig (Porcine) Crystallin, alpha B (CRYAB) Interaktionspartner

  1. This study clearly demonstrated that both the length and electrostatic charge of the COOH-terminal segment play crucial roles in governing the structural stability and chaperone activity of alphaB-crystallin.

CRYAB Antigen-Profil

Beschreibung des Gens

Crystallins are separated into two classes taxon-specific, or enzyme, and ubiquitous. The latter class constitutes the major proteins of vertebrate eye lens and maintains the transparency and refractive index of the lens. Since lens central fiber cells lose their nuclei during development, these crystallins are made and then retained throughout life, making them extremely stable proteins. Mammalian lens crystallins are divided into alpha, beta, and gamma families\; beta and gamma crystallins are also considered as a superfamily. Alpha and beta families are further divided into acidic and basic groups. Seven protein regions exist in crystallins: four homologous motifs, a connecting peptide, and N- and C-terminal extensions. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (sHSP also known as the HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone\; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits\; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. Alpha-A and alpha-B gene products are differentially expressed\; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Elevated expression of alpha-B crystallin occurs in many neurological diseases\; a missense mutation cosegregated in a family with a desmin-related myopathy.

Genbezeichner und Symbole assoziert mit Crystallin, alpha B (CRYAB) ELISA Kits

  • crystallin alpha B (CRYAB) Antikörper
  • crystallin, alpha B (Cryab) Antikörper
  • hypothetical protein (ZK1128.7) Antikörper
  • crystallin alpha B (Cryab) Antikörper
  • AACRYA Antikörper
  • CMD1II Antikörper
  • Crya-2 Antikörper
  • Crya2 Antikörper
  • CRYAB Antikörper
  • CTPP2 Antikörper
  • CTRCT16 Antikörper
  • HspB5 Antikörper
  • MFM2 Antikörper

Bezeichner auf Proteinebene für Crystallin, alpha B (CRYAB) ELISA Kits

alpha-crystallin B chain , heat shock protein beta-5 , heat-shock 20 kD like-protein , renal carcinoma antigen NY-REN-27 , rosenthal fiber component , P23 , alpha B-crystallin , alpha(B)-crystallin , crystallin, alpha 2 , Crystallin, alpha polypeptide 2 , hypothetical protein , crystallin, alpha B , alpha B crystallin , alpha-B-crystallin , alphaB-crystallin , crystallin, alpha polypeptide 2 , Alpha(B)-crystallin , Alpha-crystallin B chain

1410 Homo sapiens
12955 Mus musculus
25420 Rattus norvegicus
191528 Caenorhabditis elegans
396089 Gallus gallus
451543 Pan troglodytes
479441 Canis lupus familiaris
497274 Ovis aries
100009295 Oryctolagus cuniculus
100172850 Pongo abelii
100306972 Cavia porcellus
281719 Bos taurus
100519789 Sus scrofa
710747 Macaca mulatta
791109 Ornithorhynchus anatinus
101827485 Mesocricetus auratus
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