anti-Crossover junction endonuclease EME1 (EME1) Antikörper

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick.

Alle Antikörper anzeigen Gen GeneID UniProt
Anti-Maus EME1 EME1 268465 Q8BJW7;
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Top anti-Crossover junction endonuclease EME1 Antikörper auf antikoerper-online.de

Showing 10 out of 62 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-EME1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-EME1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- EME1 Picoband antibody,IHC(P) IHC(P): Rat Intestine Tissue Anti- EME1 Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: HeLa 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of EME1 expression in transfected 293T cell line by EME1 MaxPab polyclonal antibody.<br><br>Lane 1: EME1 transfected lysate(64.13 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to EME1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse thymus and rat thymus tissues, using EME1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

Weitere Antikörper gegen Crossover junction endonuclease EME1 Interaktionspartner

Mouse (Murine) Crossover junction endonuclease EME1 (EME1) Interaktionspartner

  1. Study found that a Gen1 mutation alone did not affect DNA repair or meiotic recombination in mice; it caused synthetic lethality when combined with Eme1 mutations at an early embryonic stage. Also, combination of Gen1 and Eme1 mutations makes embryonic fibroblasts more sensitive to DNA damage & mice less capable of meiotic recombination. These results indicate that Gen1 and Eme1 are functionally redundant in mice.

  2. indicate that SLX1 and MUS81 (zeige MUS81 Antikörper)-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4 (zeige BTBD12 Antikörper).

  3. Mus81 (zeige MUS81 Antikörper)-Eme1- and Rad54 (zeige RAD54L Antikörper)-mediated homologous recombination are involved in the same DNA replication-dependent interstrand crosslinks repair pathway

  4. These findings link Eme1 with the replication-associated chromatin modifier functions of Np95 (zeige UHRF1 Antikörper) in the cellular response to DNA damage.

Crossover junction endonuclease EME1 (EME1) Antigen-Profil

Protein Überblick

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:14609959}.

Genbezeichner und Symbole assoziert mit EME1

  • essential meiotic structure-specific endonuclease 1 (Eme1) Antikörper
  • 6820428D13 Antikörper

Bezeichner auf Proteinebene für EME1

crossover junction endonuclease EME1 , essential meiotic endonuclease 1 homolog 1

GENE ID SPEZIES
268465 Mus musculus
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