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anti-Crossover junction endonuclease EME1 (EME1) Antikörper

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Zusätzlich bieten wir Ihnen Crossover junction endonuclease EME1 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EME1 268465 Q8BJW7;
EME1    
EME1    
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Top anti-Crossover junction endonuclease EME1 Antikörper auf antikoerper-online.de

Showing 10 out of 53 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-EME1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB <b>WB Suggested Anti-EME1 Antibody Titration: </b>0.2-1 ug/ml<br><b>ELISA Titer: </b>1:312500<br><b>Positive Control: </b>HT1080 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- EME1 Picoband antibody,IHC(P) IHC(P): Rat Intestine Tissue Anti- EME1 Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: HeLa 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 1 bis 2 Tage
$358.60
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of EME1 expression in transfected 293T cell line by EME1 MaxPab polyclonal antibody.<br><br>Lane 1: EME1 transfected lysate(64.13 KDa).<br>Lane 2: Non-transfected lysate.<br> Immunofluorescence of <u>purified</u> MaxPab antibody to EME1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 7 bis 9 Tage
$551.83
Details
Maus Kaninchen Unkonjugiert WB Western blot analysis of extracts of mouse thymus and rat thymus tissues, using EME1 antibody. 100 μL Anmelden zum Anzeigen 16 Days
$334.02
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details

EME1 Antikörper nach Reaktivität, Anwendung, Klonalität and Konjugat

Attribute Applikationen Wirt Klonalität Konjugat
Mouse (Murine)


Human
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Rat (Rattus)


Weitere Antikörper gegen Crossover junction endonuclease EME1 Interaktionspartner

Mouse (Murine) Crossover junction endonuclease EME1 (EME1) Interaktionspartner

  1. Study found that a Gen1 mutation alone did not affect DNA repair or meiotic recombination in mice; it caused synthetic lethality when combined with Eme1 mutations at an early embryonic stage. Also, combination of Gen1 and Eme1 mutations makes embryonic fibroblasts more sensitive to DNA damage & mice less capable of meiotic recombination. These results indicate that Gen1 and Eme1 are functionally redundant in mice.

  2. indicate that SLX1 and MUS81 (zeige MUS81 Antikörper)-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4 (zeige BTBD12 Antikörper).

  3. Mus81 (zeige MUS81 Antikörper)-Eme1- and Rad54 (zeige RAD54L Antikörper)-mediated homologous recombination are involved in the same DNA replication-dependent interstrand crosslinks repair pathway

  4. These findings link Eme1 with the replication-associated chromatin modifier functions of Np95 (zeige UHRF1 Antikörper) in the cellular response to DNA damage.

Crossover junction endonuclease EME1 (EME1) Antigen-Profil

Protein Überblick

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:14609959}.

Genbezeichner und Symbole assoziert mit EME1

  • essential meiotic structure-specific endonuclease 1 (Eme1) Antikörper
  • 6820428D13 Antikörper

Bezeichner auf Proteinebene für EME1

crossover junction endonuclease EME1 , essential meiotic endonuclease 1 homolog 1

GENE ID SPEZIES
268465 Mus musculus
Ausgewählte Anbieter für anti-Crossover junction endonuclease EME1 (EME1) Antikörper
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