anti-Crossover junction endonuclease EME1 (EME1) Antikörper

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Zusätzlich bieten wir Ihnen Crossover junction endonuclease EME1 Proteine (4) und und viele weitere Produktgruppen zu diesem Protein an.

Alle Antikörper anzeigen Gen GeneID UniProt
EME1 268465 Q8BJW7;
EME1    
EME1    
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Top anti-Crossover junction endonuclease EME1 Antikörper auf antikoerper-online.de

Showing 10 out of 58 products:

Katalog Nr. Reaktivität Wirt Konjugat Applikation Bilder Menge Anbieter Lieferzeit Preis Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-EME1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 293T cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$289.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB WB Suggested Anti-EME1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: HT1080 cell lysate 100 μL Anmelden zum Anzeigen 2 bis 3 Tage
$319.00
Details
Human Kaninchen Unkonjugiert IHC (p), WB Anti- EME1 Picoband antibody,IHC(P) IHC(P): Rat Intestine Tissue Anti- EME1 Picoband antibody,IHC(P) IHC(P): Human Lung Cancer Tissue 100 μg Anmelden zum Anzeigen 4 bis 6 Tage
$280.00
Details
Rind (Kuh) Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, WB 100 μL Anmelden zum Anzeigen 16 Days
$181.73
Details
Fledermaus Kaninchen Unkonjugiert WB 50 μg Anmelden zum Anzeigen 11 bis 14 Tage
$551.83
Details
Human Kaninchen Unkonjugiert ELISA, ICC, IF, WB Western blot analysis of extracts from COLO cells, using EME1 antibody.The lane on the left is treated with the antigen-specific peptide. ABIN6275735 staining LOVO by IF/ICC. The sample were fixed with PFA and permeabilized in 0.1% Triton X-100,then blocked in 10% serum for 45 minutes at 25¡ãC. The primary antibody was diluted at 1/200 and incubated with the sample for 1 hour at 37¡ãC. An  Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibod 100 μL Anmelden zum Anzeigen 11 bis 12 Tage
$390.77
Details
Human Maus Unkonjugiert IF, WB Western Blot analysis of EME1 expression in transfected 293T cell line by EME1 MaxPab polyclonal antibody.Lane 1: EME1 transfected lysate(64.13 KDa).Lane 2: Non-transfected lysate. Immunofluorescence of purified MaxPab antibody to EME1 on HeLa cell. [antibody concentration 10 ug/ml] 50 μL Anmelden zum Anzeigen 11 bis 12 Tage
$440.00
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: H1299 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details
Human Kaninchen Unkonjugiert WB WB Image Sample (30 ug of whole cell lysate) A: HeLa 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Anmelden zum Anzeigen 3 bis 4 Tage
$466.18
Details

Am meisten referenzierte anti-Crossover junction endonuclease EME1 Antikörper

  1. Monoclonal EME1 Primary Antibody für WB - ABIN534210 : Vigneron, Gamelin, Coqueret: The EGFR-STAT3 oncogenic pathway up-regulates the Eme1 endonuclease to reduce DNA damage after topoisomerase I inhibition. in Cancer research 2008 (PubMed)

Weitere Antikörper gegen Crossover junction endonuclease EME1 Interaktionspartner

Mouse (Murine) Crossover junction endonuclease EME1 (EME1) Interaktionspartner

  1. Study found that a Gen1 mutation alone did not affect DNA repair or meiotic recombination in mice; it caused synthetic lethality when combined with Eme1 mutations at an early embryonic stage. Also, combination of Gen1 and Eme1 mutations makes embryonic fibroblasts more sensitive to DNA damage & mice less capable of meiotic recombination. These results indicate that Gen1 and Eme1 are functionally redundant in mice.

  2. indicate that SLX1 and MUS81-EME1 nucleases act together to resolve Holliday junctions (HJs) in a manner that requires tethering to SLX4.

  3. Mus81-Eme1- and Rad54-mediated homologous recombination are involved in the same DNA replication-dependent interstrand crosslinks repair pathway

  4. These findings link Eme1 with the replication-associated chromatin modifier functions of Np95 in the cellular response to DNA damage.

Crossover junction endonuclease EME1 (EME1) Antigen-Profil

Protein Überblick

Interacts with MUS81 to form a DNA structure-specific endonuclease with substrate preference for branched DNA structures with a 5'-end at the branch nick. Typical substrates include 3'- flap structures, replication forks and nicked Holliday junctions. May be required in mitosis for the processing of stalled or collapsed replication forks. {ECO:0000269|PubMed:14609959}.

Genbezeichner und Symbole assoziert mit EME1

  • essential meiotic structure-specific endonuclease 1 (Eme1) Antikörper
  • 6820428D13 Antikörper

Bezeichner auf Proteinebene für EME1

crossover junction endonuclease EME1 , essential meiotic endonuclease 1 homolog 1

GENE ID SPEZIES
268465 Mus musculus
Ausgewählte Anbieter für anti-Crossover junction endonuclease EME1 (EME1) Antikörper
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