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CORO1C encodes a member of the WD repeat protein family. Zusätzlich bieten wir Ihnen CORO1C Antikörper (76) und und viele weitere Produktgruppen zu diesem Protein an.
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Coronin-1C Protein and Caveolin Protein Provide Constitutive and Inducible Mechanisms of Rac1 Protein
Coronin 1C displays highly co-operative binding to actin filaments. We highlight a novel mode of coronin regulation, which has implications for how coronins orchestrate cytoskeletal dynamics.
These results indicate that glucose recruits coronin 3 near the plasma membrane, and that it regulates the retrograde transport of the secretory membrane in pancreatic beta-cells.
Coronin 3 is abundantly expressed in the adult CNS. All murine brain areas express coronin 3 during embryogenesis and the first postnatal stages.
Results indicate that interaction of GDP-Rab27a (zeige RAB27A Proteine) and coronin 3 is important in stimulus-endocytosis coupling, and that GTP (zeige AK3 Proteine)- and GDP-Rab27a (zeige RAB27A Proteine) regulates insulin (zeige INS Proteine) membrane recycling at the distinct stages.
It would appear that YB-1 (zeige YBX1 Proteine) could regulate cell invasion and migration via downregulation of its indirect target coronin-1C. The association between YB-1 (zeige YBX1 Proteine) and coronin-1C offers a novel approach by which metastasis of breast cancer cells could be targeted and abrogated.
findings emphasize the power of genetic modifiers, PLS3 (zeige PLS3 Proteine) and CORO1C, to unravel the cellular pathomechanisms underlying spinal muscular atrophy (SMA (zeige SMN1 Proteine))--and the power of combinatorial therapy based on splice correction of SMN2 (zeige SMN1 Proteine) and endocytosis improvement to efficiently treat SMA (zeige SMN1 Proteine)
Data indicate that coronin 1C protein (CORO1C) was a direct target of the microRNA miR-1/133a cluster in EBC-1 CORO1C was a direct target of the miR-1/133a cluster in lung-squamous cell carcinoma cell line EBC-1.
Coro1C mediated Rac1 trafficking through actin-rich vesicles.
Coronin-1C overexpression is associated withand hepatocellular carcinoma growth through enhancement of tumor cell proliferation and migration, which are correlated with Rac-1 activation.
Coronin 3 promotes gastric cancer metastasis via the up-regulation of MMP-9 (zeige MMP9 Proteine) and cathepsin K (zeige CTSK Proteine).
Patients with higher coronin-1C expression had a more advanced stage of hepatocellular carcinoma.
There is a strong expression of both SELPLG and coronin-1C in the majority of primary effusion lymphomas, irrespective of their gene dosage. SELPLG is critical for cell migration and chemotaxis, while CORO1C regulates actin-dependent processes.
Coronin 1C negatively regulates epithelial cell migration via FAK (zeige PTK2 Proteine)-mediated inhibition of cell-matrix adhesion.
oligomerization, F-actin interaction and membrane association are mediated by carboxyl terminus
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Three transcript variants encoding two different isoforms have been found for this gene.
coronin, actin binding protein, 1C
, coronin homolog
, coronin 1c
, coronin 3
, coronin 1C
, coronin, actin-binding protein, 1C