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COG8 encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Zusätzlich bieten wir Ihnen COG8 Antikörper (26) und viele weitere Produktgruppen zu diesem Protein an.
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The exome sequencing was performed to screen all CDG type II-related genes, and two novel frameshift mutations were found: c.171dupG (p.Leu58Alafs*29) and c.1656dupC (p.Ala553Argfs*15) in COG8.
TMED6-COG8 chimera might act as a novel diagnostic marker in TFE3 (zeige TFE3 Proteine) translocation renal cell carcinoma (zeige MOK Proteine).
Targeted silencing of components of lobe B of the COG (zeige TG Proteine) complex, namely COG5 (zeige COG5 Proteine), COG6 (zeige COG6 Proteine), COG7 (zeige COG7 Proteine) and COG8, inhibited HIV-1 replication
wthe origin, evolution and preservation of the COG8/PDF same-strand overlap follow similar mechanistic steps as those documented for antisense overlaps where gain and/or loss of splice sites and polyadenylation signals seems to drive the process.
This gene encodes a protein that is a component of the conserved oligomeric Golgi (COG) complex, a multiprotein complex that plays a structural role in the Golgi apparatus, and is involved in intracellular membrane trafficking and glycoprotein modification. Mutations in this gene cause congenital disorder of glycosylation, type IIh, a disease that is characterized by under-glycosylated serum proteins, and whose symptoms include severe psychomotor retardation, failure to thrive, seizures, and dairy and wheat product intolerance.
component of oligomeric golgi complex 8
, conserved oligomeric Golgi complex subunit 8-like
, COG complex subunit 8
, conserved oligomeric Golgi complex subunit 8
, conserved oligomeric golgi complex component 8
, dependent on RIC1
, conserved oligomeric Golgi complex protein 8